{"id":630802,"date":"2024-12-20T13:29:13","date_gmt":"2024-12-20T18:29:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630802"},"modified":"2024-12-20T13:42:09","modified_gmt":"2024-12-20T18:42:09","slug":"tizanidine-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/tizanidine-alternatives\/","title":{"rendered":"Tizanidine alternatives: What can I take instead of tizanidine?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/tizanidine-hcl\/what-is\"><span style=\"font-weight: 400;\">Tizanidine<\/span><\/a><span style=\"font-weight: 400;\"> is a generic prescription muscle relaxant available as brand-name Zanaflex, which is <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2013\/021447s011_020397s026lbl.pdf\"><span style=\"font-weight: 400;\">approved by the Food and Drug Administration (FDA)<\/span><\/a><span style=\"font-weight: 400;\"> for treating <\/span><a href=\"https:\/\/www.aans.org\/Patients\/Neurosurgical-Conditions-and-Treatments\/Spasticity\"><span style=\"font-weight: 400;\">spasticity<\/span><\/a><span style=\"font-weight: 400;\">, a condition in which muscles stiffen or tighten, preventing normal fluid movement. Tizanidine is also used<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> (for a non-FDA-approved use) for musculoskeletal pain. In addition, its sedative effects may offer relief to patients with insomnia caused by severe muscle spasms (but this benefit is also not FDA approved).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although tizanidine is effective for treating spasticity, it isn\u2019t for everyone. Its effects don&#8217;t last long, and it should be used during times when relief from muscle spasms is most needed for daily activities. It\u2019s also not ideal for people with kidney or liver problems.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Taking tizanidine with alcohol or the following medications could increase the risk of side effects like drowsiness, dizziness, and impaired coordination:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oral contraceptives (birth control pills)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Central nervous system (CNS) depressants (medicines that slow down the brain, like sedatives or sleeping pills)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Always consult your healthcare provider before taking tizanidine with any other medications or substances.<\/span><\/p>\n<p><strong>RELATED: <a href=\"https:\/\/www.singlecare.com\/blog\/tizanidine-interactions\/\">Tizanidine interactions to avoid<\/a><\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Tizanidine is generally well-tolerated, but side effects can occur. Drowsiness, dry mouth, and muscle weakness are the <\/span><a href=\"https:\/\/www.sciencedirect.com\/topics\/pharmacology-toxicology-and-pharmaceutical-science\/tizanidine\"><span style=\"font-weight: 400;\">most frequently reported side effects of tizanidine<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2 id=\"what-can-i-take-in-place-of-tizanidine\"><span style=\"font-weight: 400;\">What can I take in place of tizanidine?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you&#8217;re looking for an alternative to tizanidine due to side effects, there are other options you can discuss with your healthcare provider for treating <\/span><span style=\"font-weight: 400;\">muscle spasms, pain, and spasticity. Tizanidine al<\/span><span style=\"font-weight: 400;\">ternatives include other <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/muscle-relaxants\"><span style=\"font-weight: 400;\">muscle relaxants<\/span><\/a><span style=\"font-weight: 400;\">, medications with similar effects, and non-prescription options that may be more suitable depending on your needs.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-tizanidine-to-alternatives\"><span class=\"title\">Compare tizanidine to alternatives<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Baclofen<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Spasticity due to multiple sclerosis or certain other conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">The starting dose is 5 mg by mouth 3 times daily. The healthcare provider may gradually increase the dose as needed, up to a maximum of 20 mg by mouth 4 times daily.<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/baclofen\"><span style=\"font-weight: 400;\">Baclofen coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Chlorzoxazone<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Relief of discomfort associated with acute, painful musculoskeletal conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 250\u2013500 mg by mouth 3\u20134 times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/chlorzoxazone\"><span style=\"font-weight: 400;\">Chlorzoxazone coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Cyclobenzaprine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Relief of muscle spasms associated with acute, painful musculoskeletal conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 5 mg by mouth 3 times daily; healthcare provider may increase dose if needed (generally should not be taken for more than 3 weeks)<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/cyclobenzaprine-hcl\"><span style=\"font-weight: 400;\">Cyclobenzaprine coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dantrium<\/span><\/p>\n<p><span style=\"font-weight: 400;\">(Dantrolene)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Muscle spasticity due to conditions such as stroke, cerebral palsy, multiple sclerosis, or spinal cord injury<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 25 mg by mouth daily to start; healthcare provider may gradually increase the dosage up to a maximum of 100 mg by mouth 3 or 4 times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/dantrium\"><span style=\"font-weight: 400;\">Dantrium coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zanaflex (tizanidine)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Muscle spasticity<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 2 mg by mouth every 6 to 8 hours (maximum 3 doses per 24 hours); healthcare provider may increase the dose if needed<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zanaflex\"><span style=\"font-weight: 400;\">Zanaflex coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Metaxalone<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Relief of discomfort associated with acute, painful musculoskeletal conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 800 mg by mouth 3\u20134 times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/metaxalone\"><span style=\"font-weight: 400;\">Metaxalone coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Methocarbamol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Relief of <\/span><span style=\"font-weight: 400;\">acute, painful musculoskeletal conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Dosage varies: A typical starting dose may be 1,500 mg by mouth 4 times daily, with a decrease in dose after a few days<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/methocarbamol\"><span style=\"font-weight: 400;\">Methocarbamol coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Orphenadrine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Relief of discomfort associated with acute, painful musculoskeletal conditions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 100 mg by mouth twice daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/orphenadrine-citrate-er\"><span style=\"font-weight: 400;\">Orphenadrine coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Soma\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">(carisoprodol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Acute musculoskeletal pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Take 250\u2013350 mg by mouth 3 times daily and at bedtime<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/soma\"><span style=\"font-weight: 400;\">Soma coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Valium (diazepam)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Skeletal muscle spasm (used along with other medicine); also has other uses such as anxiety and acute alcohol withdrawal<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2 mg to 10 mg by mouth 3 or 4 times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/valium\"><span style=\"font-weight: 400;\">Valium coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"top-5-tizanidine-alternatives\"><span style=\"font-weight: 400;\">Top 5 tizanidine alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most commonly recommended alternatives to tizanidine:<\/span><\/p>\n<h3 id=\"1-baclofen\"><span style=\"font-weight: 400;\">1. Baclofen\u00a0<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/baclofen\/what-is\"><span style=\"font-weight: 400;\">Baclofen<\/span><\/a><span style=\"font-weight: 400;\"> is another muscle relaxant often prescribed to people with muscle spasticity due to multiple sclerosis or spinal cord injuries. It works by acting on the CNS to reduce muscle stiffness and improve mobility. Baclofen is typically well-tolerated but may cause drowsiness, dizziness, and weakness. It&#8217;s available in tablet form and is often taken three to four times daily.<\/span><\/p>\n<h3 id=\"2-cyclobenzaprine\"><span style=\"font-weight: 400;\">2. Cyclobenzaprine\u00a0<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/cyclobenzaprine-hcl\/what-is\"><span style=\"font-weight: 400;\">Cyclobenzaprine<\/span><\/a><span style=\"font-weight: 400;\"> is a well-studied muscle relaxant to treat and provide short-term relief from muscle spasms and pain. It has demonstrated effectiveness in managing various conditions, including low back pain, and is sometimes prescribed off-label for <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/fibromyalgia-treatment-and-medications\"><span style=\"font-weight: 400;\">fibromyalgia<\/span><\/a><span style=\"font-weight: 400;\">. Its sedative properties may also benefit individuals experiencing insomnia related to severe muscle spasms. Cyclobenzaprine is available in both immediate-release tablets and extended-release (ER) capsules, with the latter offering the convenience of once-daily dosing. Unlike tizanidine, which is more suited for treating spasticity, cyclobenzaprine is ideal for acute muscle spasms. However, it can cause side effects such as drowsiness, dry mouth, and dizziness. Individuals with hyperthyroidism, heart conditions, or liver disease should avoid it.<\/span><\/p>\n<h3 id=\"3-methocarbamol\"><span style=\"font-weight: 400;\">3. Methocarbamol\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Methocarbamol<\/span><span style=\"font-weight: 400;\"> is a muscle relaxant that works by slowing down the nervous system to reduce muscle spasms and allow the body to relax. It&#8217;s a good alternative to tizanidine for those who need a less sedative option. However, it can still cause drowsiness in some users. Methocarbamol is often prescribed for acute muscle pain due to strains or sprains and is available in tablet and injectable forms.<\/span><\/p>\n<h3 id=\"4-valium\"><span style=\"font-weight: 400;\">4. Valium\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Valium (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/diazepam\/what-is\"><span style=\"font-weight: 400;\">diazepam<\/span><\/a><span style=\"font-weight: 400;\">) is a benzodiazepine used to treat muscle spasms, alcohol withdrawal symptoms, anxiety disorders, and seizures. It works by calming the brain and nerves and relieving muscle stiffness. Valium can cause drowsiness, fatigue, and weakness, similar to tizanidine. Due to its sedative effects and potential for dependency, it&#8217;s typically prescribed for short-term use. Valium is classified as a Schedule IV <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/controlled-substances-act\/\"><span style=\"font-weight: 400;\">controlled substance<\/span><\/a><span style=\"font-weight: 400;\"> due to its potential for abuse and dependence.<\/span><\/p>\n<h3 id=\"5-metaxalone\"><span style=\"font-weight: 400;\">5. Metaxalone\u00a0<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/metaxalone\/what-is\"><span style=\"font-weight: 400;\">Metaxalone<\/span><\/a><span style=\"font-weight: 400;\"> is a muscle relaxant similar to tizanidine, primarily used to treat muscle spasms and pain. Although clinical trial data for metaxalone is limited, it may be a viable option for a muscle relaxer with fewer sedative effects. While muscle relaxants typically cause sedation, metaxalone is associated with less dizziness and drowsiness than other skeletal muscle relaxants. However, it should be avoided by those with a history of anemia, kidney issues, or liver disease.<\/span><\/p>\n<h3 id=\"over-the-counter-pain-relievers\"><span style=\"font-weight: 400;\">Over-the-counter pain relievers<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If muscle relaxants make you tired or dizzy, over-the-counter (OTC) pain relievers may be an option. OTC pain relievers like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\/what-is\"><span style=\"font-weight: 400;\">nonsteroidal anti-inflammatory drugs<\/span><\/a><span style=\"font-weight: 400;\"> (NSAIDs) or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tylenol\"><span style=\"font-weight: 400;\">Tylenol<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/acetaminophen\/what-is\"><span style=\"font-weight: 400;\">acetaminophen<\/span><\/a><span style=\"font-weight: 400;\">) can be effective in managing muscle pain. Some popular NSAIDs include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advil\"><span style=\"font-weight: 400;\">Advil<\/span><\/a> <span style=\"font-weight: 400;\">or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/motrin-ib\"><span style=\"font-weight: 400;\">Motrin<\/span><\/a><span style=\"font-weight: 400;\"> (ibuprofen), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aleve\"><span style=\"font-weight: 400;\">Aleve<\/span><\/a><span style=\"font-weight: 400;\"> (naproxen), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aspirin-low-dose\"><span style=\"font-weight: 400;\">aspirin<\/span><\/a><span style=\"font-weight: 400;\">. You can ask your healthcare provider for medical advice on which OTC pain reliever would be best for you. Your provider may recommend trying one of these medicines alone or in combination with a muscle relaxant.<\/span><\/p>\n<h2 id=\"natural-alternatives-to-tizanidine\"><span style=\"font-weight: 400;\">Natural alternatives to tizanidine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When it comes to easing muscle tension and pain, many people are turning to natural and nonprescription alternatives that offer a gentler approach to relief. Remember, before trying any new treatment, it&#8217;s always a good idea to consult your healthcare provider. They can help you determine the best approach for your needs and ensure you make safe and informed choices.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here are some alternatives:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK561514\/\"><b>Physical therapy<\/b><\/a> <span style=\"font-weight: 400;\">can help reduce pain and muscle strains. It involves strengthening muscles, improving flexibility, and teaching the body to move more efficiently.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532287\/\"><b>Acupuncture<\/b><\/a><span style=\"font-weight: 400;\"> is a traditional Chinese practice that involves inserting needles into specific points on your body. The American College of Physicians recommends it as a <\/span><a href=\"https:\/\/www.acponline.org\/acp-newsroom\/american-college-of-physicians-issues-guideline-for-treating-nonradicular-low-back-pain#:~:text=For%20patients%20with%20chronic%20low,progressive%20relaxation%2C%20electromyography%20biofeedback%2C%20low\"><span style=\"font-weight: 400;\">first-line chronic low back pain treatment<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Magnesium<\/b><span style=\"font-weight: 400;\"> is important for muscle function and may help <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8020016\/\"><span style=\"font-weight: 400;\">reduce muscle cramps and spasms<\/span><\/a><span style=\"font-weight: 400;\">. Some studies have shown that magnesium supplements can be effective for certain types of muscle pain, especially in people who are magnesium-deficient.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cannabidiol (CBD) oil<\/b><span style=\"font-weight: 400;\"> has gained attention for its potential to help with pain relief and muscle relaxation. While <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9288157\/\"><span style=\"font-weight: 400;\">more research is needed<\/span><\/a><span style=\"font-weight: 400;\">, some people find that CBD oil can be a helpful supplement.<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-switch-to-a-tizanidine-alternative\"><span style=\"font-weight: 400;\">How to switch to a tizanidine alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Discuss all your health conditions and symptoms and explain why you&#8217;re considering a switch. They can help you choose the best alternative based on your health condition and the medications you are already taking.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Suddenly stopping tizanidine without talking with your healthcare provider can lead to serious withdrawal symptoms such as increased heart rate, tremors, and anxiety. To avoid this, your healthcare provider may recommend gradually reducing your dose of tizanidine while introducing the new medication. Report any side effects or concerns you may have to your healthcare provider.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tizanidine is a generic prescription muscle relaxant available as brand-name Zanaflex, which is approved by the Food and Drug Administration (FDA) for treating spasticity, a condition in which muscles stiffen or tighten, preventing normal fluid movement. Tizanidine is also used off-label (for a non-FDA-approved use) for musculoskeletal pain. In addition, its sedative effects may offer [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":630803,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[3418],"coauthors":[21032],"class_list":["post-630802","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-generic-drugs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Tizanidine alternatives: What can I take instead of tizanidine?<\/title>\n<meta name=\"description\" content=\"Tizanidine alternatives include meds such as baclofen and cyclobenzaprine, but OTC pain medications and natural alternatives may also help with muscle spasticity.\" \/>\n<meta name=\"robots\" content=\"index, follow, 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