{"id":630867,"date":"2024-12-31T15:41:25","date_gmt":"2024-12-31T20:41:25","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630867"},"modified":"2025-01-23T11:52:39","modified_gmt":"2025-01-23T16:52:39","slug":"can-prednisone-cause-anxiety","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/can-prednisone-cause-anxiety\/","title":{"rendered":"Prednisone anxiety: Why it happens and how to cope"},"content":{"rendered":"

Prednisone<\/span><\/a> is an FDA-approved prescription medication to treat a range of common conditions characterized by inflammation caused by the immune system. It belongs to a class of drugs called <\/span>corticosteroids<\/span><\/a> (sometimes called <\/span>glucocorticoids<\/span><\/a>). Like other steroids, prednisone reduces swelling, redness, and other symptoms caused by immune system reactions. And like other drugs, <\/span>prednisone is not without its side effects<\/span><\/a>, and some people have reported <\/span>anxiety<\/span><\/a> while on prednisone.\u00a0<\/span><\/p>\n

What is anxiety?<\/span><\/h2>\n

Anxiety isn\u2019t just a feeling of being anxious or stressed out. Some people experience what\u2019s called \u201cgeneral anxiety,\u201d which <\/span>the American Psychological Association describes as \u201cpersistent, excessive worries that don\u2019t go away even in the absence of a stressor.\u201d Like stress, anxiety can include racing thoughts, feeling panicky, a fast heart rate, and even social avoidance. However, unlike stress, anxiety and panic attacks can\u2019t be traced to a clear and logical reason for the feelings. It is fuelled internally rather than externally.<\/span><\/p>\n

Can prednisone cause anxiety?<\/span><\/h2>\n

Yes, anxiety is a common side effect of prednisone and other corticosteroids, such as <\/span>dexamethasone<\/span><\/a> and cortisone.\u00a0<\/span><\/p>\n

In two large meta-analyses of corticosteroid treatment,<\/span> 28% of users reported mild to moderate psychiatric reactions<\/span><\/a>, including but not limited to anxiety. A <\/span>2023 retrospective study<\/span><\/a> of 3,138 prednisone users also found that oral corticosteroids like prednisone can induce anxiety, <\/span>panic disorder<\/span><\/a>, <\/span>depression<\/span><\/a>, and delirium.<\/span><\/p>\n

Bottom line: Anxiety is just one of several common mental health side effects of prednisone.<\/span><\/p>\n

Dethamexasone coupons<\/span><\/a><\/p>\n

Prednisone anxiety: Why it happens<\/span><\/h2>\n

So, why might prednisone-induced anxiety? Below, <\/span>Daniel Kim<\/span><\/a>, DO<\/span>, a board-certified family physician with Medical Offices of Manhattan and <\/span>LabFinder<\/span><\/a> contributor, and <\/span>Inna Melamed<\/span><\/a>, Pharm.D., functional medicine practitioner and author of <\/span>Digestive Reset, <\/span><\/i>explain.<\/span><\/p>\n

How prednisone affects the body<\/span><\/h3>\n

\u201c<\/span>Prednisone<\/span><\/a> is a synthetic version of cortisol, which controls our ‘flight or fight’ response in the brain,\u201d Dr. Kim says. \u201cIt can increase our <\/span>blood pressure<\/span><\/a>, heart rate, and alertness, which in turn can increase our feelings of anxiety.\u201d Corticosteroids like prednisone can also alter levels of the mood-regulating hormones dopamine and serotonin, according to Dr. Melamed.<\/span><\/p>\n

Ultimately, prednisone artificially and temporarily alters stress- and mood-related hormone levels. This disruption has been known to cause psychiatric complications, <\/span>including anxiety and sleep difficulties as well as delirium or even dementia<\/span><\/a>.<\/span><\/p>\n

Who is most likely to experience anxiety on prednisone?<\/span><\/h3>\n

People on high doses of prednisone are more likely to experience corticosteroid-induced anxiety than people on low doses of prednisone. Individuals who already live with anxiety may experience worsening anxiety when taking prednisone.\u00a0<\/span><\/p>\n

Dr. Kim suggests that other risk factors may include a current psychiatric disorder or a medical history of <\/span>anxiety disorder<\/span><\/a>. He also says people with chronic illnesses are at a higher risk because they are likely to be on prednisone more often or for longer. The more time a corticosteroid has to impact an individual\u2019s hormones, the more likely they are to experience side effects, including anxiety.<\/span><\/p>\n

\u201cIt is not fully conclusive, but there are some indications that women may experience anxiety more often than men when on prednisone,\u201d Dr. Kim adds.<\/span><\/p>\n

RELATED: <\/b>6 prednisone side effects in women<\/b><\/a><\/p>\n

Can coming off prednisone cause anxiety?<\/span><\/h3>\n

Unfortunately, yes. Anxiety is a common prednisone side effect, but it is also a less common symptom of <\/span>prednisone withdrawal<\/span><\/a>. Other signs of corticosteroid withdrawal include extreme fatigue, body aches, fever, and gastrointestinal discomfort.<\/span><\/p>\n

It is essential to taper off prednisone<\/span><\/a> gradually\u2014and with the guidance of a healthcare provider. This gives the adrenal system time to adjust to pre-prednisone cortisol production levels.<\/span><\/p>\n

Prednisone coupons<\/span><\/a><\/p>\n

What to do about prednisone side effects like anxiety<\/span><\/h2>\n

Prednisone is not intended to be a long-term medication. The good news is that anxiety symptoms and other side effects of corticosteroids, such as weight gain or high blood pressure, should subside after you finish your prescription.\u00a0<\/span><\/p>\n

\u201cPrednisone stays in the system for up to a day,\u201d says Dr. Melamed. \u201cIf the therapy was stopped and any side effect continues, including anxiety, then consider seeking help within a few days, especially if the anxiety is severe.\u201d<\/span><\/p>\n

Below, the experts suggest how to manage prednisone side effects like anxiety during treatment.\u00a0<\/span><\/p>\n

Natural remedies for anxiety<\/span><\/h3>\n

Dr. Kim recommends communicating your side effects closely with your healthcare provider. He also suggests Using <\/span>natural techniques to manage anxiety<\/span><\/a>, such as exercise, support groups, therapy, and good sleep hygiene.<\/span><\/p>\n

It\u2019s also a good idea to <\/span>avoid alcohol<\/span><\/a> and caffeine while taking prednisone. <\/span>Alcohol can exacerbate psychiatric symptoms<\/span><\/a>, and <\/span>caffeine<\/span><\/a> can worsen prednisone side effects.\u00a0<\/span><\/p>\n

Dosage adjustments\u00a0<\/span><\/h3>\n

High or prolonged doses of prednisone are more likely than low doses to cause side effects such as anxiety, mood swings, and other mood changes. Dr. Melamed recommends consulting a healthcare professional \u201cimmediately\u201d if prednisone anxiety is severe enough to interfere with daily functioning. In such cases, a dose adjustment might be appropriate.\u00a0<\/span><\/p>\n

Never discontinue or adjust prednisone dosage without medical guidance. Prednisone must be tapered gradually to avoid triggering withdrawal symptoms.<\/span><\/p>\n

Prednisone alternatives\u00a0<\/span><\/h3>\n

In some cases, a prednisone alternative can be prescribed to patients concerned about prednisone-induced anxiety. The best prednisone alternative depends on the condition it is being used to treat. For instance, Dr. Melamed says an <\/span>NSAID<\/span><\/a> like Motrin for inflammation or an <\/span>antirheumatic<\/span><\/a> drug like <\/span>methotrexate<\/span><\/a> for arthritis can be used with much less risk of mood-related side effects.\u00a0<\/span><\/p>\n

However, she also says prednisone is still \u201cthe drug of choice\u201d and is \u201cthe last resort\u201d for many prescribers. If a person\u2019s medical condition is severe enough to warrant corticosteroid therapy, there might not be an equally effective alternative.\u00a0<\/span><\/p>\n

Regardless of whether it is possible to reduce dosage or switch to a different prescription drug, it\u2019s essential to seek medical advice if prednisone side effects become severe. Report new symptoms of mood disorders or steroid-induced behavioral changes to your prescriber as soon as possible.<\/span><\/p>\n

Motrin coupons<\/span><\/a>, <\/span>Methotrexate coupons<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Prednisone is an FDA-approved prescription medication to treat a range of common conditions characterized by inflammation caused by the immune system. It belongs to a class of drugs called corticosteroids (sometimes called glucocorticoids). Like other steroids, prednisone reduces swelling, redness, and other symptoms caused by immune system reactions. And like other drugs, prednisone is not […]<\/p>\n","protected":false},"author":149,"featured_media":630868,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9777,12752],"coauthors":[20942],"class_list":["post-630867","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-anxiety","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"\nCan prednisone cause anxiety?<\/title>\n<meta name=\"description\" content=\"Anxiety is one side effect of prednisone, and it is more likely to occur in people taking large doses. 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