{"id":630926,"date":"2025-01-06T13:53:18","date_gmt":"2025-01-06T18:53:18","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=630926"},"modified":"2026-06-24T17:23:34","modified_gmt":"2026-06-24T21:23:34","slug":"rosuvastatin-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/rosuvastatin-alternatives\/","title":{"rendered":"Rosuvastatin (Crestor) alternatives: What can I take instead of rosuvastatin?"},"content":{"rendered":"

Rosuvastatin<\/span><\/a> is a prescription drug that lowers cholesterol levels and reduces the risk of cardiovascular events like heart attacks. The brand-name version, <\/span>Crestor<\/span><\/a>, has been around for years, but <\/span>generic rosuvastatin<\/span><\/a> is often lower-priced. Rosuvastatin is not right for everyone. It\u2019s a potent drug, so it may be more likely to cause intolerable side effects. Alternatives abound, though, and we will cover them here.<\/span><\/p>\n\t\t

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Save up to 80% on Rosuvastatin with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tRosuvastatin 10 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
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\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$7.71\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$7.71\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Rosuvastatin prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

RELATED: <\/b>Cholesterol medication coupons & resources<\/b><\/a><\/p>\n

What can I take instead of rosuvastatin?<\/span><\/h2>\n

If<\/span> rosuvastatin<\/span><\/a> does not agree with you due to side effects or cost, other statins may still be good alternatives for cholesterol. Outside of the <\/span>statin<\/span><\/a> category, <\/span>Zetia<\/span><\/a> (ezetimibe) is a common choice. <\/span>Fibrates<\/span><\/a>, such as <\/span>Lopid<\/span><\/a> (gemfibrozil), and <\/span>bile acid sequestrants<\/span><\/a>, like <\/span>Welchol<\/span><\/a> (colesevelam) and <\/span>Questran<\/span><\/a> (cholestyramine), have historically been used as alternatives to statins, but they are used less often now. <\/span>PCSK9 inhibitors<\/span><\/a> and bempedoic acid are newer drugs to consider for people looking for rosuvastatin alternatives with fewer side effects.\u00a0<\/span><\/p>\n

Deciding between the options is not easy. It is important to know whether LDL alone in hyperlipidemia needs to be lowered, or whether triglycerides, which are circulating fats, should also be reduced, as in hypertriglyceridemia. Preventing cardiovascular events, such as heart attacks or strokes, from happening or recurring is another salient goal for cholesterol medication. Let’s dive into the details of the decisions about lipid management.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
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Rosuvastatin alternatives cost comparison<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Rosuvastatin<\/span><\/td>\n$227 for 30, 10 mg tablets<\/span><\/td>\n$8 for 30, 10 mg tablets of generic rosuvastatin at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Brand-name rosuvastatin (Crestor)<\/span><\/td>\n$360 for 30, 10 mg tablets<\/span><\/td>\n$272 for 30, 10 mg tablets of brand-name Crestor at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Lipitor (atorvastatin)<\/span><\/td>\n$705 for 30, 40 mg tablets<\/span><\/td>\n$8 for 30, 40 mg tablets of generic Lipitor at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Pravastatin<\/span><\/td>\n$304 for 90, 40 mg tablets<\/span><\/td>\n$17 for 90, 40 mg tablets of generic pravastatin at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Zetia (ezetimibe)<\/span><\/td>\n$1,568 for 90, 10 mg tablets<\/span><\/td>\n$14 for 90, 10 mg tablets of generic Zetia at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Repatha (evolocumab)<\/span><\/td>\n$817 for 2, 1 mL of 140 mg\/mL syringes<\/span><\/td>\n$473 for 2, 1 mL of 140 mg\/mL syringes of brand-name Repatha at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Nexletol (bempedoic acid)<\/span><\/td>\n$592 for 30, 180 mg tablets<\/span><\/td>\n$390 for 30, 180 mg tablets of brand-name Nexletol at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Top 5 rosuvastatin alternatives<\/span><\/h2>\n

The following are some of the most common alternatives to rosuvastatin.<\/span><\/p>\n

1. Lipitor<\/span><\/h3>\n

Rosuvastatin is the most potent statin, dropping LDL levels lower than any other. A close second, <\/span>Lipitor<\/span><\/a> is the other statin that is considered when high-intensity statin therapy is needed. The two are specifically recommended in <\/span>cholesterol management guidelines<\/span><\/a> for patients with atherosclerotic cardiovascular disease or severely <\/span>elevated LDL cholesterol<\/span><\/a>. In other words, if blockages and cholesterol buildup are already present in blood vessels, or LDL levels are extreme, studies have found that these are the drugs of choice. At their lesser doses, <\/span>rosuvastatin and atorvastatin<\/span><\/a> can be used as moderate-intensity statins for less severe cases.<\/span><\/p>\n

2. Pravastatin<\/span><\/h3>\n

Pravastatin<\/span><\/a> is a lower-potency statin that, at its highest doses, can provide moderate-intensity statin therapy. One reason some choose it over rosuvastatin is its tolerability. An individual may have side effects with one statin but not another. Although rosuvastatin tends to be well-tolerated by most people, pravastatin causes few problems as well, possibly because they are both <\/span>more hydrophilic<\/span><\/a> (dissolve in water) in the body than other statins. The primary <\/span>adverse effects<\/span><\/a> of statins are muscle pain and weakness, and <\/span>liver enzyme monitoring<\/span><\/a> may be advised to watch for any uncommon but serious side effects.\u00a0<\/span><\/p>\n

3. Zetia<\/span><\/h3>\n

Sometimes, despite trying multiple statins, an individual cannot tolerate them or is unable to get their cholesterol numbers low enough. In these situations, Zetia (ezetimibe) is often called upon as an alternative or an add-on to a statin. Instead of inhibiting the HMG-CoA reductase enzyme to reduce LDL production, as a statin does, Zetia blocks intestinal cholesterol absorption. It is not as strong as rosuvastatin, but it can be used in conjunction with it if needed to reach treatment goals.<\/span><\/p>\n

4. Repatha<\/span><\/h3>\n

Repatha<\/span><\/a> (evolocumab) is one of the new, powerful cholesterol-lowering medications from the PCSK9 inhibitor class. Injected every two to four weeks, Repatha works by increasing LDL receptors in the liver, thereby clearing LDL from circulation. If rosuvastatin proves intolerable or insufficient, Repatha can be a good pick for those with coronary heart disease. Aside from the need for injections rather than tablets, Repatha\u2019s hefty price is the biggest holdback. A <\/span>SingleCare discount card<\/span><\/a> is an easy way to save money on cholesterol medicine and simply needs to be presented to your pharmacist.<\/span><\/p>\n

5. Nexletol<\/span><\/h3>\n

By inhibiting LDL synthesis, <\/span>Nexletol<\/span><\/a> (bempedoic acid) can be an effective option for managing hyperlipidemia when statins are problematic. The fact that it is new and only available as a brand-name product makes price a concern. In addition, the drug\u2019s label warns about reports of <\/span>gout<\/span><\/a> and tendon rupture with Nexletol.<\/span><\/p>\n

RELATED: <\/b>What\u2019s the safest cholesterol medication?<\/b><\/a><\/p>\n

Natural alternatives to rosuvastatin<\/span><\/h2>\n

Taking medication is not the only option for the management of high cholesterol. A <\/span>healthy diet<\/span><\/a>, such as a low-carbohydrate diet or a Mediterranean-style diet, could be quite helpful. Exercise can be incorporated, too. These lifestyle changes may not replace rosuvastatin for everyone, but they are worth discussing with your healthcare provider.<\/span><\/p>\n

Supplements are a popular topic of conversation when seeking alternatives to prescription treatments, but robust clinical trial evidence is typically lacking. To lower cholesterol, <\/span>berberine<\/span><\/a>, red yeast rice extract, and omega-3 fatty acids are common considerations. <\/span>Red yeast rice<\/span><\/a> is a natural alternative to rosuvastatin<\/span> because it\u2019s a very low-potency statin based on its mechanism of action, but shouldn\u2019t be taken instead of cholesterol medication. <\/span>Omega-3 fatty acids<\/span><\/a>, derived from fish oil, may help lower triglyceride levels. These options generally cannot replace rosuvastatin fully, and they can have side effects and drug interactions, too. Discussing them with your healthcare provider first is essential.<\/span><\/p>\n

RELATED: <\/b>The best diet for heart health<\/b><\/a><\/p>\n

How to switch to a rosuvastatin alternative<\/span><\/h2>\n

Rosuvastatin can be a vital medicine for preventing a heart attack or stroke, and as such, any decisions about stopping it should be run past the healthcare professional prescribing it. The conversation should touch on treatment goals, any other prescription and over-the-counter meds and supplements being taken, and any health conditions. If it is mutually agreed that a change is needed, rosuvastatin can be stopped abruptly without tapering. As you have seen, there are several worthy alternatives if rosuvastatin is not the right choice for you.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Rosuvastatin is a prescription drug that lowers cholesterol levels and reduces the risk of cardiovascular events like heart attacks. The brand-name version, Crestor, has been around for years, but generic rosuvastatin is often lower-priced. Rosuvastatin is not right for everyone. It\u2019s a potent drug, so it may be more likely to cause intolerable side effects. […]<\/p>\n","protected":false},"author":87,"featured_media":630927,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[4343,20952],"coauthors":[20732],"class_list":["post-630926","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-brand-name-drugs","tag-high-cholesterol","wpautop"],"acf":[],"yoast_head":"\nTop rosuvastatin (Crestor) alternatives and how to switch your Rx<\/title>\n<meta name=\"description\" content=\"Lipitor, Pravachol, Zetia, Repatha, and Nexletol are some rosuvastatin alternatives. 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