{"id":631134,"date":"2025-01-24T09:30:10","date_gmt":"2025-01-24T14:30:10","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=631134"},"modified":"2025-01-21T12:27:36","modified_gmt":"2025-01-21T17:27:36","slug":"levothyroxine-and-pregnancy","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/levothyroxine-and-pregnancy\/","title":{"rendered":"Can you take levothyroxine during pregnancy?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">About 30 million adults in the U.S. have an underactive thyroid, which means their thyroid gland doesn\u2019t produce enough thyroid hormones to keep up with the body\u2019s demands. <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/low-tsh-symptoms\"><span style=\"font-weight: 400;\">Thyroid-stimulating hormone<\/span><\/a><span style=\"font-weight: 400;\"> (TSH) is a pituitary hormone that stimulates your thyroid to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). T3 and T4 are responsible for regulating your metabolism, body temperature, growth, and energy levels. When thyroid dysfunction causes a hormonal imbalance, you may develop a thyroid disorder such as hyperthyroidism (overproduction of thyroid hormones), hypothyroidism (underproduction of thyroid hormones), or thyroid autoimmunity (autoimmune thyroid disease, or AITD).<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/living-with-hypothyroidism\/\"><span style=\"font-weight: 400;\">Hypothyroidism<\/span><\/a><span style=\"font-weight: 400;\"> is usually treated with prescription medications like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium\"><span style=\"font-weight: 400;\">levothyroxine<\/span><\/a><span style=\"font-weight: 400;\">, a synthetic thyroid hormone treatment that mimics T4. Levothyroxine is the first-line treatment for hypothyroidism. But what happens if you have an underactive thyroid during pregnancy when you have to be especially <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/safe-medication-during-pregnancy\/\"><span style=\"font-weight: 400;\">cautious about the medications you take<\/span><\/a><span style=\"font-weight: 400;\"> to avoid pregnancy complications like preterm birth and pregnancy loss?<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It happens more often than you might think, according to Libu Varughese, MD, endocrinologist and medical adviser for Aeroflow Diabetes. Hypothyroidism occurs more often in women. It\u2019s not uncommon for pregnant women to have it. It occurs in about 2% to 3% of pregnancies. The good news is that it\u2019s generally considered safe and necessary to use levothyroxine for thyroid problems. Here\u2019s why\u2014and what you can expect if you need to use this medication while pregnant.<\/span><\/p>\n<h2 id=\"hypothyroidism-during-pregnancy\"><span style=\"font-weight: 400;\">Hypothyroidism during pregnancy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Women can have hypothyroidism pre-pregnancy or may develop pregnancy-related hypothyroidism. Both mother and fetus need to have sufficient thyroid hormone levels during pregnancy. Expectant mothers who have hypothyroidism may experience <\/span><a href=\"https:\/\/www.marchofdimes.org\/find-support\/topics\/pregnancy\/thyroid-conditions-during-pregnancy\"><span style=\"font-weight: 400;\">anemia, preeclampsia, hypertension, placental abruption, and postpartum hemorrhage<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Thyroid hormones are also important to the fetus\u2019s growth and development, especially its neurological system, playing a crucial role in how the fetal brain forms and develops during pregnancy. Babies born to mothers with untreated hypothyroidism during pregnancy are more likely to have irreversible cognitive disabilities, as shown in studies like this <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4819012\/\"><span style=\"font-weight: 400;\">review<\/span><\/a><span style=\"font-weight: 400;\">, which found that moderate hypothyroidism during pregnancy (particularly in the first trimester) is associated with cognitive impairments in children born to mothers with hypothyroidism.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Untreated hypothyroidism in pregnancy is also associated with poor birth outcomes, including miscarriage, low birth weight, and preterm delivery. It also puts the pregnant person at an increased risk of gestational hypertension or high blood pressure during pregnancy.<\/span><\/p>\n<h2 id=\"can-you-take-levothyroxine-while-pregnant\"><span style=\"font-weight: 400;\">Can you take levothyroxine while pregnant?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Levothyroxine therapy is not only safe, but it\u2019s the most commonly recommended medication used to treat hypothyroidism during pregnancy, <\/span><a href=\"https:\/\/aeroflowdiabetes.com\/libu-v-endo\"><span style=\"font-weight: 400;\">Dr. Varughese<\/span><\/a><span style=\"font-weight: 400;\"> explains. Because it\u2019s a synthetic version of the same thyroid hormone your body naturally makes, it helps restore normal thyroid function without unwanted side effects.<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium\/what-is\"><span style=\"font-weight: 400;\">Levothyroxine<\/span><\/a><span style=\"font-weight: 400;\"> has a long history of safe use in pregnancy, says <\/span><a href=\"https:\/\/www.linkedin.com\/in\/rikki-baldwin-31041094\/\"><span style=\"font-weight: 400;\">Rikki Baldwin<\/span><\/a><span style=\"font-weight: 400;\">, DO, OB-GYN with Memorial Hermann Medical Group in Texas. It is the gold standard for the treatment of hypothyroidism during pregnancy, called maternal hypothyroidism. In fact, it improves birth outcomes. A <\/span><a href=\"https:\/\/bmcendocrdisord.biomedcentral.com\/articles\/10.1186\/s12902-021-00699-5\"><span style=\"font-weight: 400;\">review of studies<\/span><\/a><span style=\"font-weight: 400;\"> found that levothyroxine lowered the risk of miscarriage and newborn death associated with low thyroid levels during pregnancy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While hypothyroidism can occur at any stage of pregnancy, it\u2019s most <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/endocrine-diseases\/pregnancy-thyroid-disease\"><span style=\"font-weight: 400;\">dangerous<\/span><\/a><span style=\"font-weight: 400;\"> when onset is in the first trimester. Hypothyroidism occurring in the second trimester or third trimester is still associated with risks, but they are less severe.<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium\"><span style=\"font-weight: 400;\">Levothyroxine coupons<\/span><\/a><\/p>\n<h2 id=\"levothyroxine-dosage-during-pregnancy\"><span style=\"font-weight: 400;\">Levothyroxine dosage during pregnancy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Your body typically has a higher demand for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/hypothyroidism-and-pregnancy\/\"><span style=\"font-weight: 400;\">thyroid hormones during pregnancy<\/span><\/a><span style=\"font-weight: 400;\">, says Dr. Baldwin. This demand can increase as your pregnancy progresses. That means your pre-pregnancy dose (or starting dose if you\u2019re diagnosed during pregnancy) of levothyroxine may need to increase for the nine months you\u2019re expecting.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maternal hypothyroidism encompasses<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22191793\/\"><span style=\"font-weight: 400;\">two types of hyperthyroidism<\/span><\/a><span style=\"font-weight: 400;\">: overt hypothyroidism, characterized by clinically elevated TSH levels and low T4 levels, and subclinical hypothyroidism, with elevated TSH and normal T4 levels. Thyroid function tests performed by an endocrinology specialist can distinguish between the two forms. You may undergo the following <\/span><a href=\"https:\/\/my.clevelandclinic.org\/health\/diagnostics\/17556-thyroid-blood-tests\"><span style=\"font-weight: 400;\">tests<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/tsh-test\/\"><b>TSH tests<\/b><\/a> <span style=\"font-weight: 400;\">measure the levels of thyroid-stimulating hormones in your blood or serum TSH)<\/span><b>.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Thyroid blood tests <\/b><span style=\"font-weight: 400;\">(TSH, T3 and T4, thyroglobulin uptake test, and thyroid antibodies) check your blood for hormones and proteins like thyroxine, thyroid peroxidase antibodies, and thyroglobulin to determine if you have hypothyroidism or hyperthyroidism.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Thyroid imaging tests<\/b><span style=\"font-weight: 400;\"> use radioactive iodine to take an image of your thyroid. The scan provides further information about your thyroid function.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Always consult a healthcare professional for a definitive diagnosis. Your healthcare provider can help you determine the right treatment for your thyroid needs. Dr. Baldwin says your hormone levels can be checked every trimester to determine if your hypothyroidism is well-controlled on levothyroxine. Still, if your hormone levels are changing or your medication dosage is being slowly increased to meet your body\u2019s needs, you will likely need to have your thyroid hormone levels checked every four to six weeks.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You should also expect dosage changes again after you give birth, says Dr. Baldwin: \u201cDuring the postpartum period, your dose of levothyroxine can be decreased to pre-pregnancy levels, with hormone levels checked about two months after delivery.\u201d<\/span><\/p>\n<h2 id=\"what-are-the-risks-of-taking-levothyroxine-while-pregnant\"><span style=\"font-weight: 400;\">What are the risks of taking levothyroxine while pregnant?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Levothyroxine is safe for mothers and their growing babies during pregnancy. Pregnant women typically don\u2019t experience side effects from levothyroxine unless they are on too much or too little of the medication, says Dr. Varughese.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though levothyroxine does cross the placenta and enter the fetus\u2019s bloodstream, this is actually a good thing. Growing fetuses need the <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/endocrine-diseases\/pregnancy-thyroid-disease\"><span style=\"font-weight: 400;\">right amount of thyroid hormone<\/span><\/a><span style=\"font-weight: 400;\"> to be passed on from their mothers in utero, so when the mother\u2019s thyroid hormone levels are deficient, a fetus may not get enough thyroid hormones to develop properly.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Baldwin notes that some <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9191263\/\"><span style=\"font-weight: 400;\">scientific literature<\/span><\/a><span style=\"font-weight: 400;\"> suggests the possibility of an increased risk of gestational diabetes, taking levothyroxine during pregnancy, but also emphasizes that this complication is more likely to occur in women with untreated hypothyroidism during pregnancy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In other words, the benefits of taking levothyroxine far outweigh the risks since not treating an underactive thyroid during pregnancy is more dangerous than taking the medication.<\/span><\/p>\n<h2 id=\"what-can-i-take-instead-of-levothyroxine-during-pregnancy\"><span style=\"font-weight: 400;\">What can I take instead of levothyroxine during pregnancy?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Levothyroxine is the only medication recommended to treat underactive thyroid in pregnancy, according to Dr. Varughese. Not only does it have a well-studied safety profile, it effectively boosts a fetus\u2019s thyroid levels in ways other medications can\u2019t.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, the most common alternative, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/armour-thyroid\"><span style=\"font-weight: 400;\">Armour Thyroid<\/span><\/a><span style=\"font-weight: 400;\"> (non-synthetic natural hormone derived from pigs), is sometimes used to treat hypothyroidism, but Dr. Varughese says it\u2019s unsuitable for pregnant women because of its variable hormone content. It contains more T3 than T4, which is a problem for unborn babies; they can\u2019t utilize T3 in utero, so they need a steady supply of T4 from their mothers for their brains to develop properly. Without enough T4, <\/span><a href=\"https:\/\/www.thyroid.org\/wp-content\/uploads\/patients\/brochures\/hypothyroidism_pregnancy_faq.pdf\"><span style=\"font-weight: 400;\">a fetus could be hypothyroidic<\/span><\/a><span style=\"font-weight: 400;\"> even if the mother\u2019s thyroid hormone levels appear to be high enough.<\/span><\/p>\n<h2 id=\"natural-remedies-for-thyroid-control-during-pregnancy\"><span style=\"font-weight: 400;\">Natural remedies for thyroid control during pregnancy<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">People with an underactive thyroid need medication to get their thyroid hormone levels back to normal. Hypothyroidism is caused by a failure of the thyroid gland to function correctly, says Dr. Varughese, so the best way to replace the deficient levels of hormone is with <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/endocrine-diseases\/hypothyroidism\"><span style=\"font-weight: 400;\">hormone replacement therapy medication<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It\u2019s not recommended, Dr. Varughese adds, to try and manage hypothyroidism without medication like levothyroxine\u2014especially during pregnancy, when sufficient thyroid levels are so important for the baby\u2019s growth and development. However, that doesn\u2019t mean you can\u2019t take medication <\/span><i><span style=\"font-weight: 400;\">and <\/span><\/i><span style=\"font-weight: 400;\">boost your thyroid in other ways during pregnancy.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Make sure you get enough iodine in your diet.<\/b><span style=\"font-weight: 400;\"> This mineral helps the thyroid function correctly. Iodine-rich foods include dairy, eggs, cereal, lean poultry, iodine-enriched table salt, and seafood.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Take a prenatal vitamin<\/b><span style=\"font-weight: 400;\"> containing at least 150 micrograms of iodine.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Avoid taking levothyroxine at the same time as your prenatal vitamin<\/b><span style=\"font-weight: 400;\">; most prenatal vitamins contain nutrients like calcium and iron, which can affect how well your body absorbs your medication.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/hypothyroidism-diet\/\"><b>Avoid taking levothyroxine while consuming soy-based foods<\/b><\/a><span style=\"font-weight: 400;\">, like tofu and edamame, which can also interfere with the medication\u2019s absorption.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">While these tips are generally safe for most people to use, it\u2019s important to always discuss any home remedies or other therapies with your healthcare provider before trying them, especially if you\u2019re pregnant.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>About 30 million adults in the U.S. have an underactive thyroid, which means their thyroid gland doesn\u2019t produce enough thyroid hormones to keep up with the body\u2019s demands. Thyroid-stimulating hormone (TSH) is a pituitary hormone that stimulates your thyroid to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). T3 and T4 are responsible for [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":630950,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[790,3896,8670],"coauthors":[8860],"class_list":["post-631134","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-chronic-disease","tag-thyroid","tag-womens-health","franchise-maternal-matters","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Levothyroxine and pregnancy: What you should know<\/title>\n<meta name=\"description\" content=\"Considering taking levothyroxine for hypothyroidism during pregnancy? 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