{"id":631163,"date":"2025-02-03T09:30:19","date_gmt":"2025-02-03T14:30:19","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=631163"},"modified":"2025-01-27T12:59:21","modified_gmt":"2025-01-27T17:59:21","slug":"can-you-take-tylenol-or-ibuprofen-with-nurtec","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/can-you-take-tylenol-or-ibuprofen-with-nurtec\/","title":{"rendered":"Can you take Tylenol or ibuprofen with Nurtec?"},"content":{"rendered":"

At least 39 million Americans live with migraine headaches. At best, they\u2019re annoying, and at worst, they\u2019re debilitating. Fortunately, there are many different medications available for the treatment and prevention of migraine, like <\/span>Nurtec<\/span><\/a> orally disintegrating tablets (ODT). \u201cNurtec can be used not only at the onset of a migraine attack to relieve pain but also to prevent future migraine occurrences when taken every other day continuously,\u201d says neurologist Lauren R. Natbony, MD, the Medical Director of Integrative Headache Medicine of New York and an Assistant Clinical Professor of Neurology at the Icahn School of Medicine at Mount Sinai. \u201cThis versatility makes it an excellent option for patients requiring acute and preventive treatment in one.\u201c<\/span><\/p>\n

But what happens if you hurt your back or stub your toe while taking Nurtec (rimegepant)? Or if you have a breakthrough migraine that\u2019s just unbearable? It\u2019s perfectly safe to take another pain reliever like <\/span>Tylenol (acetaminophen)<\/span><\/a> or <\/span>ibuprofen<\/span><\/a> while on Nurtec. Here\u2019s everything you need to know.<\/span><\/p>\n

Combining Nurtec with over-the-counter pain relievers<\/span><\/h2>\n

\u201cYou can take as-needed <\/span>OTC pain relievers<\/span><\/a>, like acetaminophen or ibuprofen, while<\/span><\/p>\n

taking Nurtec ODT,\u201d affirms Luke Hentrich, Pharm.D., an Assistant Professor in the Department of Clinical Pharmacy and Translational Science at The University of Tennessee Health Science Center College of Pharmacy. Nurtec belongs to a drug class called <\/span>calcitonin gene-related peptide (CGRP) receptor<\/span><\/a> antagonists, also known as gepants. While it\u2019s important to talk to your healthcare provider or pharmacist before combining medications, there are no known drug interactions between gepants and over-the-counter pain relievers. According to the <\/span>patient information for Nurtec<\/span><\/a>, the only reason listed for which people should not take the medication is if they have known allergic reactions to rimegepant or one of the other ingredients.<\/span><\/p>\n

\u201cIf you do need to take another pain reliever with Nurtec, the safest OTC pain relievers are acetaminophen, ibuprofen, or naproxen,\u201d <\/span>Dr. Natbony<\/span><\/a> says. Naproxen is sold under the brand name Aleve, while ibuprofen is the active ingredient in Advil and Motrin. However, it\u2019s important not to overdo it with OTC pain relievers.<\/span><\/p>\n

However, there is one caveat: <\/span>rebound headaches<\/span><\/a> when the medication wears off. \u201cTaking OTC pain relievers more than 15 days per month may lead to what is known as medication overuse headache,\u201d notes <\/span>Dr. Hentrich<\/span><\/a>. If you are already dealing with migraine headaches, that\u2019s the last thing you want.<\/span><\/p>\n

Nurtec coupons<\/span><\/a>, <\/span>Naproxen coupons<\/span><\/a>, <\/span>Ibuprofen coupons<\/span><\/a><\/p>\n

Precautions and contraindications while on Nurtec<\/span><\/h2>\n

Nurtec is broken down in the liver by the CYP3A4 enzyme. For this reason, any medications, supplements, or foods that interfere with this enzyme should be avoided while you\u2019re taking Nurtec. Drugs that inhibit the action of this enzyme may increase levels of Nurtec in your body and increase side effects. Drugs that induce the action of this enzyme reduce levels of Nurtec and make it less effective. Some examples include:<\/span><\/p>\n