{"id":631260,"date":"2025-02-04T14:46:35","date_gmt":"2025-02-04T19:46:35","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=631260"},"modified":"2026-01-28T14:13:51","modified_gmt":"2026-01-28T19:13:51","slug":"farxiga-vs-jardiance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/farxiga-vs-jardiance\/","title":{"rendered":"Farxiga vs. Jardiance: Key differences, uses, and side effects"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/farxiga\"><span style=\"font-weight: 400;\">Farxiga<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/jardiance\"><span style=\"font-weight: 400;\">Jardiance<\/span><\/a><span style=\"font-weight: 400;\"> are two brand-name oral medications approved by the U.S. Food and Drug Administration (FDA) to manage <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Type 2 diabetes mellitus<\/span><\/a><span style=\"font-weight: 400;\">. Both are <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/sglt2-inhibitors\"><span style=\"font-weight: 400;\">sodium-glucose cotransporter 2 (SGLT2) inhibitors<\/span><\/a><span style=\"font-weight: 400;\">. Farxiga, manufactured by AstraZeneca, contains the active drug dapagliflozin, and Jardiance, manufactured by Boehringer Ingelheim Pharmaceuticals, contains the active drug empagliflozin. Both drugs facilitate blood glucose (sugar) control in Type 2 diabetes mellitus by increasing urinary glucose, eliminating more sugar from the body. Although both drugs work similarly for glycemic control, there are some differences. Continue reading to learn more about Farxiga and Jardiance.<\/span><\/p>\n<h2 id=\"what-are-the-main-differences-between-farxiga-and-jardiance\"><span style=\"font-weight: 400;\">What are the main differences between Farxiga and Jardiance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although Farxiga and Jardiance are in the same drug class and have the same mechanism of action, they contain two different active ingredients and have important differences.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"main-differences-of-farxiga-and-jardiance\">Main differences of Farxiga and Jardiance<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Farxiga<\/b><\/td>\n<td><b>Jardiance<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">SGLT2 inhibitor<\/span><\/td>\n<td><span style=\"font-weight: 400;\">SGLT2 inhibitor<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic available<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand only<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Dapagliflozin<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Empagliflozin<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet: 5 mg, 10 mg<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Oral tablet: 10 mg, 25 mg<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">5 or 10 mg once daily, depending on the condition being treated<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10 or 25 mg once daily\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children 10 years and older<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children 10 years and older for Type 2 diabetes; adults only for all other uses<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"conditions-treated-by-farxiga-and-jardiance\"><span style=\"font-weight: 400;\">Conditions treated by Farxiga and Jardiance<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Farxiga (dapagliflozin) and Jardiance (empagliflozin) are both prescription drugs approved by the FDA to lower blood sugar levels in those with Type 2 diabetes mellitus. Each has additional specific uses as described below.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Farxiga is additionally FDA approved to:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">lower the chances of heart-related deaths and hospital visits for adults with heart failure and<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">reduce the risk of hospital visits due to heart failure in adults with Type 2 diabetes who have existing heart disease or multiple heart risk factors.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Jardiance is additionally FDA approved for use:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">in people with Type 2 diabetes and heart disease to lower the risk of cardiovascular death and reduce the risk of hospitalization,\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">to reduce the risk of further worsening of kidney disease, end-stage kidney disease, death due to cardiovascular disease, and hospitalization in adults with chronic kidney disease and<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">to reduce the risk of cardiovascular death in adults with Type 2 diabetes and who also have known cardiovascular disease.<\/span><\/li>\n<\/ul>\n<h2 id=\"is-farxiga-or-jardiance-more-effective\"><span style=\"font-weight: 400;\">Is Farxiga or Jardiance more effective?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While no direct head-to-head clinical studies have been performed, the efficacy of both <\/span><a href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/2042098614551938\"><span style=\"font-weight: 400;\">Farxiga<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40265-018-0937-z\"><span style=\"font-weight: 400;\">Jardiance<\/span><\/a><span style=\"font-weight: 400;\"> was established in separate clinical trials that showed similar effectiveness in lowering blood sugar levels in diabetes patients and comparable safety profiles. In these studies, none of the efficacy measurements for diabetes management showed significant differences between individuals receiving Farxiga or Jardiance.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/article-abstract\/2829196\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> was designed to compare the use of Invokana (canagliflozin), another SGLT2 inhibitor, or Farxiga with Jardiance for occurrence of myocardial infarction (MI) or stroke, or heart failure hospitalization. For MI or stroke risk, Farxiga was comparable to Jardiance. For heart failure hospitalization, those on Farxiga had a higher risk than those on Jardiance, particularly at the lower 5 mg dose of Farxiga.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are many factors to consider when determining the most appropriate drug treatment options for a condition such as Type 2 diabetes. The choice should be made in consultation with your healthcare provider, who knows your medical condition, medical history, and medicines you may already be taking that could interact with Farxiga or Jardiance.\u00a0<\/span><\/p>\n<h2 id=\"coverage-and-cost-comparison-of-farxiga-vs-jardiance\"><span style=\"font-weight: 400;\">Coverage and cost comparison of Farxiga vs. Jardiance<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many insurance plans, including Medicare Part D plans, cover Farxiga and Jardiance, but out-of-pocket costs vary by plan. Jardiance is a more expensive drug than Farxiga since it is only available in a brand-name form. Farxiga does have a generic version, which may be a more affordable option for some people.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\"><a href=\"https:\/\/www.singlecare.com\/blog\/jardiance-without-insurance\/\">Without insurance<\/a> coverage, the prices of Farxiga and Jardiance can vary depending on the pharmacy and location. At the time of publication, the average retail price of Farxiga was $808 for 30, 10 mg tablets, and for Jardiance, $862 for 30, 25 mg tablets. You may save on these medications by using SingleCare coupons for <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/farxiga\"><span style=\"font-weight: 400;\">Farxiga<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/jardiance\"><span style=\"font-weight: 400;\">Jardiance<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/jardiance-copay-assistance\/\"><b>Jardiance copay assistance: Eligibility &amp; more<\/b><\/a><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"farxiga-versus-jardiance-costs\">Farxiga versus Jardiance costs<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Farxiga<\/b><\/td>\n<td><b>Jardiance<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">30, 10 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">30, 25 mg tablets<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$355<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$497<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"common-side-effects-of-farxiga-vs-jardiance\"><span style=\"font-weight: 400;\">Common side effects of Farxiga vs. Jardiance<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Common potential side effects of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/farxiga-side-effects\/\"><span style=\"font-weight: 400;\">Farxiga<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/jardiance-side-effects\/\"><span style=\"font-weight: 400;\">Jardiance<\/span><\/a><span style=\"font-weight: 400;\"> are similar since they are in the same drug class and work the same way. The most common adverse reactions are nausea, more frequent urination, urinary tract infections (UTIs), genital fungal infections (greater incidence in women), and upper respiratory infections.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both drugs can have more serious side effects, such as diabetic ketoacidosis, serious UTIs,\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">loss of fluids (hypovolemia), and low blood sugar (hypoglycemia), though these are not as common. As with any medicine, in rare cases, a serious allergic reaction may occur. If you have symptoms such as hives or itching, difficulty breathing or swallowing, or swelling of the face, lips, tongue, or throat, seek emergency medical attention.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This is not a full list of adverse effects, and others may occur. Consult your healthcare professional for more information about side effects.<\/span><\/p>\n<h2 id=\"drug-interactions-of-farxiga-vs-jardiance\"><span style=\"font-weight: 400;\">Drug interactions of Farxiga vs. Jardiance<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because Farxiga and Jardiance are in the same drug class, they share the same potential drug interactions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The risk of low blood sugar (hypoglycemia) is increased when Farxiga or Jardiance are used in combination with other <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">diabetes medications<\/span><\/a><span style=\"font-weight: 400;\"> such as insulin, metformin, or sulfonylureas.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Taking Farxiga or Jardiance with <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lithium\/what-is\"><span style=\"font-weight: 400;\">lithium<\/span><\/a><span style=\"font-weight: 400;\"> may decrease serum lithium concentrations.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some who take Farxiga or Jardiance with <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/diuretics\"><span style=\"font-weight: 400;\">diuretics<\/span><\/a><span style=\"font-weight: 400;\"> (water pills) may have more frequent urination and an increased volume of urine, which may result in dehydration.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This is not a full list of drug interactions. Consult your healthcare professional for more information about drug interactions and how they may affect you.\u00a0<\/span><\/p>\n<h2 id=\"warnings-of-farxiga-and-jardiance\"><span style=\"font-weight: 400;\">Warnings of Farxiga and Jardiance<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It is not recommended to take SGLT2 inhibitors such as Farxiga or Jardiance in those with the following conditions:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Renal impairment (reduced kidney function)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Type 1 diabetes mellitus<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetic ketoacidosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Volume depletion (dehydration)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Although there is little research linking Farxiga or Jardiance to birth defects or miscarriages, women in the second or third trimester of pregnancy should not take Farxiga or Jardiance. It is generally recommended that women who are in the first trimester of pregnancy or who are breastfeeding should use an alternative medication to SGLT2 inhibitors.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your healthcare provider may have you stop taking Farxiga or Jardiance prior to any surgery or hospitalizations.\u00a0<\/span><\/p>\n<h2 id=\"frequently-asked-questions-about-farxiga-vs-jardiance\"><span style=\"font-weight: 400;\">Frequently asked questions about Farxiga vs. Jardiance<\/span><\/h2>\n<h3 id=\"what-is-farxiga\"><span style=\"font-weight: 400;\">What is Farxiga?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Farxiga, an SGLT2 inhibitor, is a prescription medication that lowers high blood sugar levels in those with Type 2 diabetes by promoting the elimination of glucose through the urine. Farxiga is also<\/span><span style=\"font-weight: 400;\"> approved to reduce the risk of hospitalization from heart failure<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"what-is-jardiance\"><span style=\"font-weight: 400;\">What is Jardiance?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Jardiance, an SGLT2 inhibitor, is a prescription medication that lowers high blood sugar levels in those with Type 2 diabetes by promoting the elimination of glucose through the urine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Jardiance is also approved to reduce the risk of death from heart attacks, stroke, and heart failure.<\/span><\/p>\n<h3 id=\"are-farxiga-and-jardiance-the-same\"><span style=\"font-weight: 400;\">Are Farxiga and Jardiance the same?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Farxiga and Jardiance are both in the class of drugs known as SGLT2 inhibitors but have different active ingredients. Farxiga, manufactured by AstraZeneca, contains the active drug dapagliflozin. Jardiance, manufactured by Boehringer Ingelheim Pharmaceuticals, contains the active drug empagliflozin.<\/span><\/p>\n<h3 id=\"is-farxiga-or-jardiance-better\"><span style=\"font-weight: 400;\">Is Farxiga or Jardiance better?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Both Farxiga and Jardiance are effective medications for treating Type 2 diabetes and for treating certain types of heart conditions. Since they work in the same way, one is not necessarily better than the other. Consult with your healthcare professional to determine which might be the best choice for your particular condition.<\/span><\/p>\n<h3 id=\"can-i-use-farxiga-or-jardiance-with-alcohol\"><span style=\"font-weight: 400;\">Can I use Farxiga or Jardiance with alcohol?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Farxiga and Jardiance are not known to interact with alcohol. However, your healthcare professional may advise you to avoid or limit alcohol use because it may increase the risk of some side effects of the medicines.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Farxiga and Jardiance are two brand-name oral medications approved by the U.S. Food and Drug Administration (FDA) to manage Type 2 diabetes mellitus. Both are sodium-glucose cotransporter 2 (SGLT2) inhibitors. Farxiga, manufactured by AstraZeneca, contains the active drug dapagliflozin, and Jardiance, manufactured by Boehringer Ingelheim Pharmaceuticals, contains the active drug empagliflozin. Both drugs facilitate blood [&hellip;]<\/p>\n","protected":false},"author":85,"featured_media":631261,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[10298],"coauthors":[20733],"class_list":["post-631260","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-diabetes","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Farxiga or Jardiance: Compare effectiveness, cost &amp; risks<\/title>\n<meta name=\"description\" content=\"Compare Farxiga and Jardiance, two SGLT2 inhibitors for Type 2 diabetes and heart conditions. 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