{"id":631354,"date":"2025-02-11T16:21:27","date_gmt":"2025-02-11T21:21:27","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=631354"},"modified":"2025-02-11T16:21:27","modified_gmt":"2025-02-11T21:21:27","slug":"prednisone-side-effects-uti","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/prednisone-side-effects-uti\/","title":{"rendered":"Can prednisone cause a UTI?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">Prednisone<\/span><\/a><span style=\"font-weight: 400;\"> is a generic corticosteroid that\u2019s approved to treat various medical conditions, primarily those dealing with the immune system and that cause inflammation. Examples include asthma, autoimmune diseases, rheumatoid arthritis, and certain cancers. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\/what-is\"><span style=\"font-weight: 400;\">Prednisone<\/span><\/a><span style=\"font-weight: 400;\"> is a generic medication that is also sold under the brand names Omnipred, Millipred, Econopred, Flo-Pred, Orapred, and Pediapred.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">One characteristic of prednisone is that it can suppress your immune system, making you more vulnerable to infections, including urinary tract infections (UTIs). However, not everyone who takes prednisone will experience infections. Here\u2019s what we know.<\/span><\/p>\n<h2 id=\"a-prednisone-uti-why-it-may-happen\"><span style=\"font-weight: 400;\">A prednisone UTI: Why it may happen<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Prednisone, as well as other corticosteroids, can increase the risk of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/uti-causes\"><span style=\"font-weight: 400;\">UTIs<\/span><\/a><span style=\"font-weight: 400;\"> in certain individuals. But there are various factors at play, and prednisone doesn\u2019t cause UTIs in everyone who takes it.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.uhhospitals.org\/doctors\/Sheyn-David-1912131665\"><span style=\"font-weight: 400;\">David Sheyn<\/span><\/a><span style=\"font-weight: 400;\">, MD, an OB-GYN and associate professor of urology at Case Western Reserve University says certain people are simply more prone to UTIs in general. For example, females are more likely than men to get UTIs, as are people who use urinary catheters or have had previous urologic surgery.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/houmanmd.com\/\"><span style=\"font-weight: 400;\">Justin Houman<\/span><\/a><span style=\"font-weight: 400;\">, MD, a urologist at Tower Urology and assistant professor of Urology at Cedars-Sinai Medical Center, explains that prednisone itself doesn\u2019t directly cause you to get a UTI. \u201cHowever, it can increase the risk of UTIs in certain individuals because it suppresses the immune system,\u201d he says. \u201cBy lowering your body\u2019s ability to fight infections, prednisone can make you more susceptible to bacterial overgrowth and infections, including in the urinary tract.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It&#8217;s important to understand that it\u2019s<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/things-to-avoid-while-taking-prednisone\/\"><span style=\"font-weight: 400;\">prednisone\u2019s job to suppress the immune system<\/span><\/a><span style=\"font-weight: 400;\"> in order to reduce inflammation in certain conditions. \u201cWhile this is beneficial for managing conditions like autoimmune diseases or allergies, it can also impair the body&#8217;s ability to fight off bacteria in the urinary tract,\u201d Dr. Houman says. For some people, prednisone also alters the balance of bacteria in the body, which increases the risk of infections like UTIs.\u00a0<\/span><\/p>\n<h2 id=\"other-prednisone-side-effects\"><span style=\"font-weight: 400;\">Other prednisone side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like any other prescription medication,<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/prednisone-side-effects\/\"><span style=\"font-weight: 400;\">prednisone can cause side effects.<\/span><\/a><span style=\"font-weight: 400;\"> The probability of side effects occurring is dependent on how long you\u2019ve been taking the medication, with<\/span> <a href=\"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2821349\"><span style=\"font-weight: 400;\">longer durations more likely to cause side effects<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIn general, short-term use of steroids is considered fairly safe,\u201d Dr. Sheyn says. \u201cIt is important to know that when doctors prescribe steroids, we use the shortest possible duration and lowest possible dose to treat a specific condition and always monitor for serious side effects (which are generally considered uncommon).\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition to an <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4751577\/\"><span style=\"font-weight: 400;\">increased risk of infections<\/span><\/a><span style=\"font-weight: 400;\"> when taking prednisone, the following are other potential side effects to watch for, according to Dr. Houman:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Respiratory and skin infections due to immune suppression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated blood sugar levels (hyperglycemia), especially people with diabetes or who are at risk for diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain and fluid retention due to changes in metabolism and sodium retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood swings, anxiety, and sleep disturbances like insomnia due to impacts on the central nervous system<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis or weakened bones, which can occur after long-term use<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-manage-prednisone-side-effects\"><span style=\"font-weight: 400;\">How to manage prednisone side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While prednisone can be a useful medication for many people, it\u2019s essential to be mindful of potential side effects and keep in touch with your healthcare provider for side effect management. Without careful management, you are more likely to experience adverse effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cTaking the lowest effective dose for the shortest duration possible is a key strategy,\u201d Dr. Houman says. Research has found that high doses of prednisone\u2014such as<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK534809\/\"><span style=\"font-weight: 400;\">40 mg or more per day<\/span><\/a><span style=\"font-weight: 400;\">\u2014for prolonged periods are more likely to cause serious side effects.<\/span><\/p>\n<h2 id=\"how-to-treat-a-prednisone-uti\"><span style=\"font-weight: 400;\">How to treat a prednisone UTI<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cWe would not treat UTIs any differently in someone taking prednisone or other steroids compared to someone not on these medications,\u201d Dr. Sheyn explains. Treating UTIs typically involves the use of antibiotics. <\/span><a href=\"https:\/\/www.ajog.org\/article\/S0002-9378(21)00446-4\/abstract\"><span style=\"font-weight: 400;\">First-line antibiotics for uncomplicated UTIs<\/span><\/a><span style=\"font-weight: 400;\"> include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nitrofurantoin\"><span style=\"font-weight: 400;\">nitrofurantoin<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/fosfomycin-tromethamine\"><span style=\"font-weight: 400;\">fosfomycin<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/bactrim\"><span style=\"font-weight: 400;\">Bactrim<\/span><\/a><span style=\"font-weight: 400;\"> (trimethoprim-sulfamethoxazole). You should consult with your healthcare provider about the best antibiotic for you.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In addition, if you are taking prednisone and are concerned about getting a UTI, you can take steps to prevent it.<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557479\/\"><span style=\"font-weight: 400;\">Some UTI prevention tips<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increasing fluid intake to about two liters per day<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wiping from front to back after urination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Using gentle, unscented soaps<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Avoiding the use of reusable sponges or loofahs while bathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Taking showers instead of baths<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinating after sexual intercourse<\/span><\/li>\n<\/ul>\n<h2 id=\"prednisone-alternatives\"><span style=\"font-weight: 400;\">Prednisone alternatives\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you are experiencing serious side effects from prednisone, talk to your healthcare provider about <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prednisone-alternatives\/\"><span style=\"font-weight: 400;\">prednisone alternatives<\/span><\/a><span style=\"font-weight: 400;\">. You may still be at higher risk for UTIs with other medications that suppress the immune system. The best option for you will depend on various factors, including the condition you\u2019re treating and other medications you may be taking.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Dr. Houman, the following medications may be good prednisone alternatives for people who are experiencing adverse side effects:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs (NSAIDs), such as<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> or<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen\"><span style=\"font-weight: 400;\">naproxen<\/span><\/a><span style=\"font-weight: 400;\">, for milder cases of inflammation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Disease-modifying antirheumatic drugs (DMARDs) like<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/methotrexate\"><span style=\"font-weight: 400;\">methotrexate<\/span><\/a><span style=\"font-weight: 400;\"> for autoimmune diseases<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Biologics like <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-much-does-cyltezo-cost-without-insurance\/\"><span style=\"font-weight: 400;\">Cyltezo<\/span><\/a><span style=\"font-weight: 400;\"> (adalimumab-adbm) for autoimmune diseases<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Topical steroids for localized skin conditions\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low-dose immunomodulators to balance immune activity with less pronounced immunosuppression, which means decreased chances of infection<\/span><\/li>\n<\/ul>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While prednisone doesn\u2019t directly cause UTIs, it can suppress your immune system, making you more likely to get an infection. However, not everyone gets infections while taking prednisone. Some people are more susceptible to UTIs, especially if they are taking prednisone long-term or in high doses. If you are experiencing a UTI during or after taking prednisone, contact your healthcare provider for treatment. UTIs can be treated with antibiotics. And your healthcare provider can help manage your prednisone use to minimize side effects like UTIs.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prednisone is a generic corticosteroid that\u2019s approved to treat various medical conditions, primarily those dealing with the immune system and that cause inflammation. Examples include asthma, autoimmune diseases, rheumatoid arthritis, and certain cancers. Prednisone is a generic medication that is also sold under the brand names Omnipred, Millipred, Econopred, Flo-Pred, Orapred, and Pediapred. One characteristic [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":631356,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[3418,8670],"coauthors":[20899],"class_list":["post-631354","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-generic-drugs","tag-womens-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can prednisone cause a UTI?<\/title>\n<meta name=\"description\" content=\"Prednisone doesn\u2019t directly cause UTIs, but because it works by suppressing the immune system, UTIs are a possibility in some people.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" 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