{"id":632183,"date":"2025-05-15T09:30:05","date_gmt":"2025-05-15T13:30:05","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632183"},"modified":"2025-07-24T14:06:54","modified_gmt":"2025-07-24T18:06:54","slug":"how-long-can-wegovy-be-out-of-the-fridge","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/how-long-can-wegovy-be-out-of-the-fridge\/","title":{"rendered":"How long can Wegovy be out of the fridge?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\"> (semaglutide) is a once-weekly <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/save-on-weight-loss-medication\/\"><span style=\"font-weight: 400;\">weight-loss medication<\/span><\/a><span style=\"font-weight: 400;\"> that belongs to a class of drugs called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/glp-1-agonists\"><span style=\"font-weight: 400;\">GLP-1 agonists<\/span><\/a><span style=\"font-weight: 400;\">. It is FDA approved for weight management and to reduce the risk of stroke, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cardiac-arrest-vs-heart-attack\/\"><span style=\"font-weight: 400;\">heart attack<\/span><\/a><span style=\"font-weight: 400;\">, or other <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/wegovy-heart-disease-fda-approval\/\"><span style=\"font-weight: 400;\">cardiovascular death<\/span><\/a><span style=\"font-weight: 400;\"> in people who are overweight or have obesity. Wegovy is self-injected at home, so users must know how to properly store their single-dose injector pens before use. According to the drug\u2019s manufacturer, Novo Nordisk, Wegovy pens should be refrigerated, but they can safely be left out of the fridge for up to 28 days.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Wegovy with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tWegovy 2.4 mg\/0.75 mL (4 Pens)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$1170.27<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/wegovy#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$1170.27<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/wegovy#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/wegovy#blog-cta\" class=\"coupon-see-all-btn\">See Wegovy prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"does-wegovy-need-to-be-refrigerated\"><span style=\"font-weight: 400;\">Does Wegovy need to be refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Wegovy does not need to be continuously refrigerated, but Novo Nordisk recommends refrigeration. Refrigerating the drug ensures that it stays at a consistent temperature until use.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Specifically, the manufacturer suggests storing Wegovy between 36 and 46 degrees Fahrenheit, a standard refrigerator temperature range. (The FDA recommends setting refrigerators at or below 40 F.) However, the company also states that Wegovy can be stored with the pen cap on in temperatures up to 86 F for up to 28 days.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In all cases, you should store <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\/dosage\"><span style=\"font-weight: 400;\">Wegovy pens<\/span><\/a><span style=\"font-weight: 400;\"> with the cap on \u201cto ensure it remains sterile,\u201d says Cynthia Odogwu, MD, a Maryland family and lifestyle medicine provider. This medication should also be kept in its original carton to protect against direct sunlight.<\/span><\/p>\n<h2 id=\"how-long-can-wegovy-be-out-of-the-fridge\"><span style=\"font-weight: 400;\">How long can Wegovy be out of the fridge?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cOnce [Wegovy] has been opened and left out at room temperature, it should be used within 28 days,\u201d says <\/span><a href=\"https:\/\/www.linkedin.com\/in\/cynthia-odogwu-md-02334252\/\"><span style=\"font-weight: 400;\">Dr. Odogwu<\/span><\/a><span style=\"font-weight: 400;\">. Once Wegovy has been opened and unrefrigerated, putting it back into the fridge will not extend its shelf life beyond those 28 days, according to<\/span> <a href=\"https:\/\/www.gutsygirlmd.com\/\"><span style=\"font-weight: 400;\">Supriya Rao, MD<\/span><\/a><span style=\"font-weight: 400;\">, a board-certified gastroenterologist and obesity medicine provider in Massachusetts.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you plan to travel by car or train with Wegovy, Dr. Rao suggests keeping it in an insulated cooler bag with an ice pack. \u201cAvoid freezing, and never store it in a hot car,\u201d she says.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When traveling by plane, store Wegovy in its original container in your carry-on luggage, and be prepared to declare it to security personnel at the TSA screening. Avoid putting Wegovy in your checked luggage, which may freeze at high altitudes. The goal is to keep the injection pens at a cool and consistent temperature. \u201cYou can always pack a travel thermometer if needed,\u201d says Dr. Rao. Also, remember to pack a sharps disposal container for used injection pens.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"what-happens-if-wegovy-is-not-refrigerated\"><span style=\"font-weight: 400;\">What happens if Wegovy is not refrigerated?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Drs. Odogwu and Roa agree: The main problem with leaving Wegovy out of the fridge for too long is that it might make the drug less effective. Like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zepbound\"><span style=\"font-weight: 400;\">Zepbound<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mounjaro\"><span style=\"font-weight: 400;\">Mounjaro<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/save-on-wegovy\/\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\"> is an expensive prescription drug. Reducing the drug\u2019s potency with improper storage can be a costly mistake. \u201cIt doesn\u2019t become inherently harmful, but it may not work as intended,\u201d says Dr. Rao.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Odogwu adds that keeping a drug too warm\u2014in this case, above 86 F or unrefrigerated for more than 28 days\u2014can increase the risk of contamination, which ultimately raises the risk of an <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-injection-site\/\"><span style=\"font-weight: 400;\">injection site<\/span><\/a><span style=\"font-weight: 400;\"> infection.<\/span><\/p>\n<h3 id=\"potential-side-effects\"><span style=\"font-weight: 400;\">Potential side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Wegovy that is unrefrigerated for too long will lose its effectiveness, but it\u2019s not likely to cause additional <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\">. Regardless of Wegovy storage practices, serious side effects such as <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/low-blood-sugar-symptoms\"><span style=\"font-weight: 400;\">hypoglycemia<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/who-should-not-take-wegovy\/#wegovy-warnings-in-specific-populations\"><span style=\"font-weight: 400;\">gallbladder issues, pancreatitis, and thyroid problems<\/span><\/a><span style=\"font-weight: 400;\"> should be reported to a healthcare professional immediately.\u00a0<\/span><\/p>\n<h2 id=\"how-to-know-if-wegovy-has-gone-bad\"><span style=\"font-weight: 400;\">How to know if Wegovy has gone bad<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It\u2019s not easy to tell if Wegovy has gone bad, say Drs. Odogwu and Rao. The drug is not likely to change in appearance or smell even if it has lost its potency. That said, you should throw it away immediately if you notice any changes from its standard clear, colorless appearance.<\/span><\/p>\n<h3 id=\"how-long-does-wegovy-last-in-the-fridge\"><span style=\"font-weight: 400;\">How long does Wegovy last in the fridge?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">When stored continuously in the fridge, a Wegovy pen will be good until the expiration date on the product. However, if stored at room temperature between 36 F and 86 F, the pen should be good for 28 days. \u201cIf it\u2019s been stored improperly or you\u2019re unsure about how long it\u2019s been out, it\u2019s always safest to dispose of it and use a new pen,\u201d says Dr Rao.<\/span><\/p>\n<h2 id=\"the-bottom-line\"><span style=\"font-weight: 400;\">The bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Wegovy can be kept out of the fridge for up to 28 days, but only in certain conditions. It should be stored with the cap on in its original container and away from light in a place that remains above 46 F and below 86 F.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Seek personalized medical advice from your prescriber if you have specific questions about proper Wegovy storage, Wegovy shelf life, expiration dates, or administration instructions.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wegovy (semaglutide) is a once-weekly weight-loss medication that belongs to a class of drugs called GLP-1 agonists. It is FDA approved for weight management and to reduce the risk of stroke, heart attack, or other cardiovascular death in people who are overweight or have obesity. Wegovy is self-injected at home, so users must know how [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":632169,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,21067,8905,9825],"coauthors":[20942],"class_list":["post-632183","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-glp-1-drugs","tag-seasonal","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How long can Wegovy be out of the fridge?<\/title>\n<meta name=\"description\" content=\"Wegovy can be kept out of the fridge for up to 28 days, but only under the right conditions. 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