{"id":632242,"date":"2025-05-09T18:35:52","date_gmt":"2025-05-09T22:35:52","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632242"},"modified":"2026-07-09T18:57:09","modified_gmt":"2026-07-09T22:57:09","slug":"qulipta-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/qulipta-alternatives\/","title":{"rendered":"Qulipta alternatives: What can I take instead of Qulipta?"},"content":{"rendered":"

Qulipta<\/a> (atogepant) is a brand-name prescription medication used to prevent both chronic and episodic migraine headaches<\/a>. Qulipta is a type of calcitonin gene-related peptide (CGRP) receptor antagonist<\/a>. These drugs block the action of a substance, CGRP, that provokes many of the symptoms of migraines, particularly pain. In this way, once-daily doses of Qulipta oral tablets help reduce the frequency and intensity of migraine headaches. Qulipta, though, may not be the best nor most affordable treatment for everyone. There are many alternatives, including nonpharmaceutical interventions that can help.<\/p>\n\t\t

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Save up to 80% on Qulipta with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tQulipta 60 mg (28 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$1018.14\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$1018.14\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Qulipta prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

RELATED: <\/b>Migraine financial assistance and resources<\/b><\/a><\/p>\n

What can I take instead of Qulipta?<\/h2>\n

Other options are available for migraine prevention. These alternative migraine preventive drugs include other CGRP receptor antagonists, as well as a select group of beta blockers<\/a>, antidepressants<\/a>, blood pressure medications<\/a>, and anti-seizure drugs<\/a>. Due to their different uses, side effect profiles, dosages, and costs, these options may be more suitable for certain individuals.<\/p>\n

RELATED: <\/b>Your guide to the newest migraine medications<\/b><\/b><\/a><\/p>\n\n\n\n\n\n\n\n\n\n\n\n
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Compare Qulipta alternatives<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Qulipta<\/td>\n$1,598 per 30, 60 mg tablets<\/td>\n$1,018 per 30, 60 mg tablets of brand-name Qulipta at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Nurtec ODT (rimegepant)<\/td>\n$1,417 for 8 orally disintegrating tablets\u00a0<\/td>\n$923 for 8 orally disintegrating tablets of brand-name Nurtec at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Aimovig (erenumab)<\/td>\n$1,059 for 1, 1 mL of 140 mg\/mL injection pen<\/p>\n

(1 month supply)<\/td>\n

$768 for 1, 1 mL of 140 mg\/mL injection pen of brand-name Aimovig at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Ajovy (fremanezumab)<\/td>\n$1,049 for 1, 1.5 mL of 225 mg\/1.5 mL injection pen<\/p>\n

(1 month supply)<\/td>\n

$690 for 1, 1.5 mL of 225 mg\/1.5 mL injection pen of brand-name Ajovy at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Emgality (galcanezumab)<\/td>\n$1,006 for 1, 1 mL of 120 mg\/mL autoinjector (1 month supply)<\/td>\n$622 for 1, 1 mL of 120 mg\/mL autoinjector of brand-name Emgality at CVS Pharmacy<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Inderal LA (long-acting propranolol)<\/td>\n$2,290 for 30, 60 mg capsules<\/td>\n$14 for 30, 60 mg capsules of generic Inderal LA at Walgreens<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Top 5 Qulipta alternatives<\/h2>\n

The following are some of the most common alternatives to Qulipta.<\/p>\n

1. Nurtec<\/h3>\n

Nurtec<\/a> (rimegepant) is a prescription medication used to treat and prevent migraine headaches. It is currently only available as a brand-name drug. Like Qulipta, Nurtec is an oral CGRP receptor antagonist. The American Headache Society<\/a> states that CGRP receptor antagonists should be considered a first-line approach for migraine prevention, as their efficacy, tolerability, and safety exceed those of any other preventive treatment.\u00a0<\/p>\n

In a clinical study<\/a>, participants assigned to receive Nurtec 75 mg every other day for twelve weeks had a greater reduction in migraine days per month than those assigned to placebo (4.3 fewer days versus 3.5 fewer days).\u00a0<\/p>\n

Common side effects of Nurtec<\/a> include nausea, indigestion, and abdominal pain. For migraine prevention, Nurtec is taken once every other day by mouth and is available as an oral disintegrating tablet (ODT). For acute migraine treatment, Nurtec is taken as needed at the first sign of migraine symptoms.\u00a0<\/p>\n

Nurtec<\/a> is a suitable Qulipta alternative for people who would like to continue taking oral medication.<\/p>\n

RELATED: <\/b>Qulipta vs. Nurtec: differences and similarities explained\u00a0<\/b><\/a><\/p>\n

2. Aimovig<\/h3>\n

Aimovig<\/a> (erenumab) is a brand-name injectable CGRP receptor antagonist medication that can both prevent episodic and chronic migraines. This alternative comes in an auto-injector containing the medication in solution form that is injected under the skin in the abdomen, thigh, or upper arm.\u00a0<\/p>\n

Aimovig was the first FDA-approved CGRP receptor antagonist in 2018. Clinical studies<\/a> have shown that at a monthly dose of 70 mg or 140 mg, Aimovig significantly reduced migraine frequency, the effects of migraines on daily activities, and the use of acute migraine-specific medication over six months.\u00a0<\/p>\n

Aimovig is generally well-tolerated, can be administered at home, and is safe. This alternative is conveniently administered once a month<\/a>, and a healthcare provider will provide proper injection training before the first use. Like Qulipta, Aimovig may cause hypertension<\/a>, so it\u2019s recommended to monitor for the onset or worsening of hypertension.\u00a0<\/p>\n

Aimovig<\/a> is a well-suited alternative for those who have not responded to other migraine prevention treatments and are tolerant of injections.<\/p>\n

RELATED: <\/b>How to save on Aimovig\u00a0<\/b><\/a><\/p>\n

3. Ajovy<\/h3>\n

Ajovy<\/a> (fremanezumab) is another brand-name injectable CGRP receptor antagonist medication that is recommended for episodic and chronic migraine prevention. Ajovy comes in two different subcutaneous (administered under the skin) forms: an auto-injector and a prefilled syringe.\u00a0<\/p>\n

This alternative has two convenient dosing options: once a month or once every three months. Ajovy has shown long-term efficacy<\/a> in trials, with both quarterly and monthly dosing well tolerated and sustained improvements in monthly migraine days, headache days, and headache-related disability for up to 12 months in patients with migraine. The most common side effect of Ajovy and other injectable CGRP receptor antagonists is injection-site reactions like pain and redness.\u00a0<\/p>\n

Ajovy<\/a> may be suitable for those who prefer less frequent dosing and are comfortable with giving themselves injections.<\/p>\n

4. Emgality<\/h3>\n

Emgality<\/a> (galcanezumab) is the third injectable CGRP receptor antagonist medication used to prevent both episodic and chronic migraines. Emgality also has a unique dose<\/a> approved for preventing cluster headaches<\/a>, a rare and severe type of headache. This injectable alternative is available as an auto-injector and a prefilled syringe. After an initial loading dose (a higher starter dose), Emgality is administered once a month<\/a>.\u00a0<\/p>\n

A clinical trial<\/a> evaluating people who have failed at least two to four other migraine preventative drug categories found Emgality was safe and well-tolerated. It concluded that Emgality is an important treatment option for those who have not benefited from or tolerated previous standard-of-care treatments.<\/p>\n

5. Propranolol (Inderal LA)<\/h3>\n

Propranolol<\/a> is a generic prescription oral medication available in extended-release formulation (Inderal LA<\/a>) and immediate-release formulation. Propranolol is a beta blocker that can be used to prevent migraines, as well as to treat hypertension<\/a>, angina (chest pain associated with coronary artery disease), cardiac arrhythmias, and tremor, and to reduce death post-heart attack. Beta blockers like propranolol are about 50% effective<\/a> at producing a greater-than-50 % reduction in migraine frequency. It\u2019s important to know that it often takes several weeks to notice improvement in headaches with beta blockers.<\/p>\n

Propranolol<\/a> is available as both an oral tablet and a capsule, depending on the formulation. The extended-release formulation is taken once daily, and the immediate-release formulation is taken 2 or 3 times daily.\u00a0<\/p>\n

Beta blockers like propranolol can have many common side effects<\/a>, such as dizziness, fatigue, low blood pressure (hypotension), and changes in heart rate. This may be a suitable alternative for people who have not responded to other migraine medications.<\/p>\n

RELATED: <\/b>Propranolol side effects<\/b><\/a><\/p>\n

Natural alternatives to Qulipta<\/h2>\n

Alternative remedies are an important part of migraine prevention. A variety of migraine and headache guidelines from clinical organizations recommend education and lifestyle modifications that can improve the quality of life for those with migraines.<\/p>\n

The American Headache Society emphasizes the importance of migraine treatment plans that include identifying and minimizing exposure to migraine triggers, proper nutrition, regular exercise, adequate hydration, adequate sleep, stress management, and a migraine diary. Common migraine triggers<\/a> include changes in sleep schedule, dehydration, hormone changes, stress, an increase in caffeine or alcohol intake, weather changes, and certain smells.<\/p>\n

Supplements, such as magnesium oxide<\/a>, may also be considered or added to help prevent migraines. The American Migraine Foundation<\/a> considers magnesium oxide supplements a reasonable prevention option for people with a history of aura (visual or sensory disturbances before or after migraines) and migraines related to menstruation. This supplement is available in several oral forms, such as tablets and capsules, and the usual dose for migraine prevention is 400-600 mg per day.<\/p>\n

How to switch to a Qulipta alternative<\/h2>\n

1. Discuss all health conditions with a healthcare provider<\/h3>\n

Before switching from Qulipta to an alternative, the healthcare provider should be aware of all medical conditions. Some alternatives should be used with caution or avoided with certain medical conditions.<\/p>\n

2. Do not suddenly stop taking Qulipta without medical advice<\/h3>\n

While Qulipta can be safely discontinued and is not believed to cause withdrawal effects, it\u2019s important for a migraine prevention plan to be established to avoid an abrupt increase in the strength or frequency of migraines. If the healthcare provider has been consulted and decided that stopping the medication is appropriate, Qulipta can be safely stopped.<\/p>\n

3. Discuss all prescription and over-the-counter medications with a healthcare provider<\/h3>\n

Before switching from Qulipta to an alternative, the healthcare provider must review a complete medication list, including prescription and over-the-counter (OTC) medications and supplements. Certain alternatives have dangerous drug interactions that should be avoided.<\/p>\n

4. Continue to improve lifestyle changes and avoid migraine triggers<\/h3>\n

Following lifestyle changes and continuing to avoid migraine triggers are important for people treating and preventing migraines. Stay hydrated, manage stress, and maintain a healthy sleep schedule. Healthcare providers and pharmacists can advise on migraine prevention and provide resources for migraine diaries<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Qulipta (atogepant) is a brand-name prescription medication used to prevent both chronic and episodic migraine headaches. Qulipta is a type of calcitonin gene-related peptide (CGRP) receptor antagonist. These drugs block the action of a substance, CGRP, that provokes many of the symptoms of migraines, particularly pain. In this way, once-daily doses of Qulipta oral tablets […]<\/p>\n","protected":false},"author":137,"featured_media":632243,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[4316],"coauthors":[20740],"class_list":["post-632242","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-migraine","wpautop"],"acf":[],"yoast_head":"\nTop Qulipta alternatives and how to switch your Rx<\/title>\n<meta name=\"description\" content=\"Nurtec, Aimovig, Ajovy, Emgality, and propranolol are some Qulipta alternatives. 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