{"id":632242,"date":"2025-05-09T18:35:52","date_gmt":"2025-05-09T22:35:52","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632242"},"modified":"2025-05-09T18:35:52","modified_gmt":"2025-05-09T22:35:52","slug":"qulipta-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/qulipta-alternatives\/","title":{"rendered":"Qulipta alternatives: What can I take instead of Qulipta?"},"content":{"rendered":"

Qulipta<\/span> (<\/span>atogepant<\/span>) is a <\/span>brand-name<\/span> prescription medication used to prevent <\/span>migraine headaches<\/span><\/a> (both chronic and <\/span>episodic migraines<\/span>). Currently, <\/span>Qulipta<\/span><\/a> is not available as a generic medicine. <\/span>Qulipta<\/span> is a type of <\/span>calcitonin gene-related peptide<\/span> (<\/span>CGRP<\/span>) receptor <\/span>antagonist<\/span>. Migraines are associated with increased levels of a protein called <\/span>CGRP<\/span> in the brain, and <\/span>Qulipta<\/span> helps to block <\/span>CGRP receptors<\/span> from being activated. As a result, pain and inflammation associated with <\/span>migraine attacks<\/span> can be alleviated. <\/span>Qulipta<\/span> is available as an <\/span>oral tablet<\/span> that is taken once daily.<\/span><\/p>\n

RELATED: <\/b>How much is <\/b>Qulipta<\/b> without insurance?<\/b><\/a><\/p>\n

While an effective treatment for some people, <\/span>Qulipta<\/span> may not be the best and safest treatment for everyone for preventing migraines. The <\/span>most common side effects<\/span> of <\/span>Qulipta<\/span> are nausea, <\/span>constipation<\/span>, and fatigue. People should avoid or be cautious when using <\/span>Qulipta<\/span> if they have liver problems or kidney impairment. Those with high <\/span>blood pressure<\/span> (<\/span>hypertension<\/span><\/a>) are at risk of worsening high <\/span>blood pressure<\/span> while taking <\/span>Qulipta<\/span>. Some people may seek out a more convenient dosing schedule and prefer medications with less frequent dosing. <\/span>Healthcare providers<\/span> help make <\/span>preventative treatment<\/span> plans individualized from person to person, as everyone will have different medication needs and responses.<\/span><\/p>\n

What can I take in place of <\/span>Qulipta<\/span>?<\/span><\/h2>\n

Other options are available for <\/span>migraine prevention<\/span> that do not improve with <\/span>Qulipta<\/span>. These alternative prescription medications include other <\/span>CGRP receptor antagonists<\/span>, certain beta blockers, certain antidepressants, certain <\/span>blood pressure<\/span> medications, and certain anti-seizure drugs. Due to their different uses, <\/span>side effect<\/span> profiles, dosages, and costs, these options may be more suitable for certain individuals.<\/span>
\n<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Compare Qulipta alternatives<\/span><\/th>\n<\/tr>\n<\/thead>\n
Drug name<\/b><\/td>\nUses<\/b><\/td>\nDosage<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Qulipta<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/td>\n-Take 10 mg, 30 mg or 60 mg tablet by mouth once daily (depending on type of migraine)<\/span><\/td>\nQulipta <\/span>coupons<\/span><\/a><\/td>\n<\/tr>\n
Aimovig<\/span> (<\/span>erenumab<\/span>)<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/td>\n-Inject 70 mg or 140 mg subcutaneously (under the skin) once a month<\/span><\/td>\nAimovig<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Ajovy<\/span> (<\/span>fremanezumab<\/span>)<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/td>\n-Inject 225 mg subcutaneously (under the skin) once a month or inject 675 mg subcutaneously (under the skin) every 3 months<\/span><\/td>\nAjovy <\/span>coupons<\/span><\/a><\/td>\n<\/tr>\n
Depakote ER (divalproex sodium)<\/span><\/td>\n-Bipolar disorder<\/span><\/p>\n

-Epilepsy<\/span><\/p>\n

–<\/span>Migraine prevention<\/span><\/td>\n

-Migraine dosage:\u00a0<\/span><\/p>\n

Take 500 mg to 1,000 mg by mouth once daily<\/span><\/td>\n

Depakote ER coupons<\/span><\/a><\/td>\n<\/tr>\n
Emgality<\/span> (<\/span>galcanezumab<\/span>)<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/p>\n

-Cluster headache prevention<\/span><\/td>\n

-Migraine dosage:\u00a0<\/span><\/p>\n

Inject 240 mg subcutaneously (under the skin) as a single loading dose, followed by 120 mg once a month<\/span><\/p>\n

-Cluster headache dosage:\u00a0<\/span><\/p>\n

Inject 300 mg subcutaneously (under the skin) at the onset of the cluster period, and then monthly until the end of the cluster period<\/span><\/td>\n

Emgality<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Inderal LA (propranolol)\u00a0<\/span><\/td>\n-Angina<\/span><\/p>\n

-Essential tremor<\/span><\/p>\n

-Hypertension<\/span><\/p>\n

–<\/span>Migraine prevention<\/span><\/td>\n

–<\/span>Migraine prevention<\/span>: Take 40 mg to 240 mg by mouth per day in one to four divided doses based on formulation<\/span><\/td>\nInderal LA coupons<\/span><\/a><\/td>\n<\/tr>\n
Lopressor (metoprolol tartrate)<\/span><\/td>\n-Angina<\/span><\/p>\n

-Hypertension<\/span><\/p>\n

–<\/span>Migraine prevention<\/span><\/p>\n

-Reduce the risk of death after a heart attack (myocardial infarction)<\/span><\/td>\n

–<\/span>Migraine prevention<\/span>: Take 25 mg to 100 mg by mouth twice daily<\/span><\/td>\nLopressor coupons<\/span><\/a><\/td>\n<\/tr>\n
Nurtec (<\/span>rimegepant<\/span>)<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/p>\n

–<\/span>Acute migraine treatment<\/span><\/td>\n

-Prevention dosage: Take 75 mg tablet by mouth every other day<\/span><\/p>\n

-Treatment dosage: Take 75 mg tablet by mouth as a single dose at first sign of a migraine\u00a0<\/span><\/td>\n

Nurtec ODT <\/span>coupons<\/span><\/a><\/td>\n<\/tr>\n
Timolol<\/span><\/td>\n-Hypertension<\/span><\/p>\n

–<\/span>Migraine prevention<\/span><\/p>\n

-Reduce the risk of death after a heart attack (myocardial infarction)<\/span><\/td>\n

–<\/span>Migraine prevention<\/span>: Take 10 mg to 30 mg by mouth per day in two divided doses<\/span><\/td>\nTimolol coupons<\/span><\/a><\/td>\n<\/tr>\n
Topamax (topiramate)<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/p>\n

-Seizures<\/span><\/td>\n

–<\/span>Migraine prevention<\/span>: Take 100 mg by mouth per day in one to two divided doses based on formulation<\/span><\/td>\nTopamax coupons<\/span><\/a><\/td>\n<\/tr>\n
Vyepti<\/span> (<\/span>eptinezumab<\/span>)<\/span><\/td>\n–<\/span>Migraine prevention<\/span><\/td>\n-Health provider administers 100 mg intravenously every 3 months<\/span><\/td>\nVyepti<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Other alternatives to <\/span>Qulipta<\/span><\/h3>\n

Other alternatives to <\/span>Qulipta<\/span> can help prevent migraines. Alternatives include oral <\/span>prescription drugs<\/span> used <\/span>off-label<\/span><\/a> for <\/span>migraine prevention<\/span> and injectable options given by a <\/span>healthcare provider<\/span>. <\/span>Acute treatment of migraine<\/span> can be useful for sudden <\/span>migraine pain<\/span> and is used as needed, such as <\/span>triptans<\/span> (like <\/span>sumatriptan<\/span><\/a> or <\/span>eletriptan<\/span><\/a>), <\/span>Ubrelvy<\/span><\/a> (<\/span>ubrogepant<\/span>), <\/span>Zavzpret<\/span><\/a> (<\/span>zavegepant<\/span>), or <\/span>Reyvow<\/span><\/a> (<\/span>lasmiditan<\/span>).<\/span><\/p>\n

Oral <\/span>prescription drugs<\/span>:<\/span><\/p>\n