{"id":632354,"date":"2025-05-23T20:15:09","date_gmt":"2025-05-24T00:15:09","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632354"},"modified":"2025-05-23T20:15:09","modified_gmt":"2025-05-24T00:15:09","slug":"ozempic-vs-wegovy-vs-mounjaro","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/ozempic-vs-wegovy-vs-mounjaro\/","title":{"rendered":"Ozempic vs. Wegovy vs. Mounjaro: What\u2019s the difference?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you have <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Type 2 diabetes<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/obesity-statistics\/\"><span style=\"font-weight: 400;\">obesity<\/span><\/a><span style=\"font-weight: 400;\">, you have probably heard about these once-weekly injections used to treat one or both conditions: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic\/what-is\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\/what-is\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mounjaro\/what-is\"><span style=\"font-weight: 400;\">Mounjaro<\/span><\/a><span style=\"font-weight: 400;\">. These brand-name medications belong to different, but overlapping drug classes and work similarly to stimulate insulin production, resulting in lower blood sugar and reduced appetite. Ozempic and Mounjaro are FDA-approved to treat <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/diabetes-statistics\/\"><span style=\"font-weight: 400;\">diabetes<\/span><\/a><span style=\"font-weight: 400;\">, while Wegovy is an FDA-approved <\/span><a href=\"https:\/\/www.singlecare.com\/resources\/weight-loss\"><span style=\"font-weight: 400;\">weight loss medication<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although these medications are used for similar purposes, they differ in several ways, including their active ingredients, potential side effects, and likelihood of insurance coverage.<\/span><\/p>\n<h2 id=\"what-are-the-main-differences-between-ozempic-wegovy-and-mounjaro\"><span style=\"font-weight: 400;\">What are the main differences between Ozempic, Wegovy, and Mounjaro?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ozempic, Wegovy, and Mounjaro are similar drugs, but they are not identical to one another. The main differences when comparing these injectable medications are their active ingredients, drug classifications, and FDA-approved purposes.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Active ingredient.<\/b><span style=\"font-weight: 400;\"> Ozempic and Wegovy are both brand-name forms of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/semaglutide-tablets-vs-injection\/\"><span style=\"font-weight: 400;\">semaglutide<\/span><\/a><span style=\"font-weight: 400;\">, their active ingredient. Mounjaro\u2019s active ingredient is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tirzepatide\"><span style=\"font-weight: 400;\">tirzepatide<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Drug classification. <\/b><span style=\"font-weight: 400;\">Ozempic and Wegovy\u2019s active ingredient, semaglutide, targets glucagon-like peptide-1 (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/glp-1-agonists\"><span style=\"font-weight: 400;\">GLP-1<\/span><\/a><span style=\"font-weight: 400;\">) receptors and is classified as a GLP-1 receptor agonist. In contrast, Mounjaro\u2019s active ingredient, tirzepatide, targets GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors. This categorizes it as a dual GIP\/GLP receptor agonist.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Approved uses.<\/b><span style=\"font-weight: 400;\"> Ozempic and Mounjaro are FDA-approved treatments for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/normal-blood-glucose-levels\/\"><span style=\"font-weight: 400;\">blood sugar control<\/span><\/a><span style=\"font-weight: 400;\">. Wegovy is an approved weight management medication.<\/span><\/li>\n<\/ul>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th><span class=\"title\">Comparing Ozempic vs. Wegovy vs. Mounjaro<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Ozempic<\/b><\/td>\n<td><b>Wegovy<\/b><\/td>\n<td><b>Mounjaro<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">GLP-1 receptor agonist<\/span><\/td>\n<td><span style=\"font-weight: 400;\">GLP-1 receptor agonist<\/span><\/td>\n<td><span style=\"font-weight: 400;\">GLP-1 and GIP receptor agonist<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/p>\n<p><b>Or<\/b><\/p>\n<p><b>What is the brand name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Semaglutide<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Semaglutide<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Tirzepatide<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Subcutaneous injection<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Subcutaneous injection<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Subcutaneous injection<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">The starting dose is 0.25 mg injected under the skin once weekly for 4 weeks.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Over time and depending on the treatment response, the dosage is increased to 0.5 mg-2 mg injected once a week.<\/span><\/td>\n<td><span style=\"font-weight: 400;\">The starting dose is 0.25 mg injected under the skin once weekly for 4 weeks.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Over time and depending on the treatment response, the dosage is then increased to 0.5 mg-2.4 mg once weekly.<\/span><\/td>\n<td><span style=\"font-weight: 400;\">The starting dose is 2.5 mg injected under the skin once weekly for 4 weeks.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Over time and depending on the treatment response, the dosage is increased in 2.5 mg increments up to a maximum of 15 mg once weekly.<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults 18 years and older<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children 12 years and older<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults 18 years and older<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"comparing-fda-approval-ozempic-vs-wegovy-vs-mounjaro\"><span style=\"font-weight: 400;\">Comparing FDA approval: Ozempic vs. Wegovy vs. Mounjaro<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Of these three medications, only Ozempic and Mounjaro are approved to<\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"> <span style=\"font-weight: 400;\">treat Type 2 diabetes<\/span><\/a><span style=\"font-weight: 400;\">, and only Wegovy is approved<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/save-on-wegovy\/\"> <span style=\"font-weight: 400;\">for weight loss<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"fda-approved-diabetes-treatment\"><span style=\"font-weight: 400;\">FDA-approved diabetes treatment<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">According to drug manufacturer Novo Nordisk, Ozempic<\/span><a href=\"https:\/\/www.novomedlink.com\/diabetes\/products\/treatments\/ozempic.html\"> <span style=\"font-weight: 400;\">is currently approved for three uses<\/span><\/a><span style=\"font-weight: 400;\"> in adults with Type 2 diabetes:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Improving blood sugar levels (when used alongside lifestyle changes like diet and exercise)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reducing the risk of heart attack, stroke, and other major cardiovascular disease problems in adults with Type 2 diabetes and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/heart-disease-statistics\/\"><span style=\"font-weight: 400;\">heart disease<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/news\/ozempic-kidney-disease-fda-approval\/\"><span style=\"font-weight: 400;\">Preventing worsening chronic kidney disease<\/span><\/a><span style=\"font-weight: 400;\"> (CKD) and kidney failure in adults with Type 2 diabetes and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/chronic-kidney-disease\/\"><span style=\"font-weight: 400;\">CKD<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">According to drug manufacturer Eli Lilly, Mounjaro is only approved<\/span><a href=\"https:\/\/mounjaro.lilly.com\/\"> <span style=\"font-weight: 400;\">to improve blood sugar control<\/span><\/a><span style=\"font-weight: 400;\"> in adults with Type 2 diabetes.<\/span><\/p>\n<h3 id=\"fda-approved-weight-management-treatment\"><span style=\"font-weight: 400;\">FDA-approved weight management treatment<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Wegovy, also made by Novo Nordisk, is approved for the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Managing weight in people who are <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/pharmacist-role-in-obesity-management\/\"><span style=\"font-weight: 400;\">obese<\/span><\/a><span style=\"font-weight: 400;\"> (a body mass index, or BMI, of &gt;30)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Managing weight in people who are overweight with a BMI of at least 27 and at least one weight-related health condition, such as <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/hypertension-treatments-and-medications\"><span style=\"font-weight: 400;\">high blood pressure<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/high-cholesterol-treatment-and-medications\"><span style=\"font-weight: 400;\">high cholesterol<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lowering the risk of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cardiac-arrest-vs-heart-attack\/\"><span style=\"font-weight: 400;\">heart attack<\/span><\/a><span style=\"font-weight: 400;\">, stroke, and other major <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/signs-of-heart-problems\/\"><span style=\"font-weight: 400;\">cardiovascular problems<\/span><\/a><span style=\"font-weight: 400;\"> in people who are overweight or obese and have heart disease\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ozempic and Mounjaro are sometimes prescribed <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> for weight loss. It&#8217;s unlikely for Wegovy to be prescribed off-label for diabetes because it is less likely to be covered by insurance.\u00a0<\/span><\/p>\n<h3 id=\"fda-approved-age-populations\"><span style=\"font-weight: 400;\">FDA-approved age populations<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Another difference in FDA approval is age. Ozempic and Mounjaro are approved for use in adults 18 and older, while<\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/215256s007lbl.pdf\"> <span style=\"font-weight: 400;\">Wegovy is approved for adults and children 12 and older<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"which-medication-is-most-effective-for-weight-loss\"><span style=\"font-weight: 400;\">Which medication is most effective for weight loss?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Though all three of these medications are effective for weight loss, &#8220;tirzepatide works better,&#8221; says<\/span><a href=\"http:\/\/www.instagram.com\/thehomecookingdoc\"> <span style=\"font-weight: 400;\">Cynthia Odogwu, MD<\/span><\/a><span style=\"font-weight: 400;\">, a family and lifestyle medicine physician in Maryland. The increased effectiveness is likely because tirzepatide products like Mounjaro target two metabolic hormone receptors \u2014 GIPs and GLP-1s \u2014 compared to semaglutide products like Ozempic and Wegovy, which only target GLP-1s.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Let&#8217;s take a look at clinical trials on these drugs:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In a<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34170647\/\"> <span style=\"font-weight: 400;\">40-week study<\/span><\/a><span style=\"font-weight: 400;\"> comparing the effectiveness of tirzepatide and semaglutide in patients with Type 2 diabetes, tirzepatide users lost an average of 2-6 kg (4.4-13.2 lbs) more than semaglutide users, depending on the dosage. Higher doses resulted in more weight loss.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In a<\/span><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2032183\"> <span style=\"font-weight: 400;\">68-week clinical study<\/span><\/a><span style=\"font-weight: 400;\"> comparing Wegovy (semaglutide) with a placebo, about 69% of Wegovy users lost 10% or more of their body weight compared to 12% of placebo users who lost about the same body weight percentage.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In<\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jamainternalmedicine\/fullarticle\/2821080\"> <span style=\"font-weight: 400;\">a cohort study<\/span><\/a><span style=\"font-weight: 400;\"> of 18,386 adults with overweight or obesity, the average reduction in body weight after three months of treatment for tirzepatide users was 5.9% compared to 3.6% for semaglutide users.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">As for comparing <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-vs-ozempic\/\"><span style=\"font-weight: 400;\">Ozempic vs Wegovy<\/span><\/a><span style=\"font-weight: 400;\">? &#8220;Both these medications have semaglutide as the active ingredient. They are just different brands,&#8221; emphasizes<\/span><a href=\"https:\/\/www.marisalandetta.com\/\"> <span style=\"font-weight: 400;\">Marisa Landetta, RD<\/span><\/a><span style=\"font-weight: 400;\">, a registered dietitian specializing in weight management in Lehi, Utah. Ultimately, the weight loss effectiveness of Ozempic versus Wegovy comes down to dosage.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It&#8217;s important to remember that Ozempic and Mounjaro are meant for diabetes rather than weight loss. Wegovy has the same active ingredient as Ozempic and is an FDA-approved weight loss drug. Tirzepatide, the active ingredient in Mounjaro, is also available as a weight loss drug under the brand name<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zepbound\"> <span style=\"font-weight: 400;\">Zepbound<\/span><\/a><span style=\"font-weight: 400;\">. Another GLP-1 receptor agonist that has been approved for weight loss is called<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/saxenda\"> <span style=\"font-weight: 400;\">Saxenda<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/liraglutide\"><span style=\"font-weight: 400;\">liraglutide<\/span><\/a><span style=\"font-weight: 400;\">). Ultimately, you should seek personalized medical advice for the best weight loss treatment for you.<\/span><\/p>\n<h2 id=\"dosing-and-administration\"><span style=\"font-weight: 400;\">Dosing and administration<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ozempic, Wegovy, and Mounjaro are all administered via once-weekly subcutaneous self-injection. They are all <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-long-do-you-take-wegovy-for-weight-loss\/\"><span style=\"font-weight: 400;\">intended for long-term use<\/span><\/a><span style=\"font-weight: 400;\">. They all start at a lower dose that is gradually increased depending on the treatment response.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic\/dosage#ozempic-dosage-chart\"><span style=\"font-weight: 400;\">Ozempic dosage<\/span><\/a><span style=\"font-weight: 400;\"> starts at 0.25 mg and maxes out at 2 mg injected once weekly, while<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\/dosage#Wegovy-dosage-chart-for-adults\"> <span style=\"font-weight: 400;\">Wegovy dosage<\/span><\/a><span style=\"font-weight: 400;\"> starts at 0.25 mg and can be increased to a maximum dose of 2.4 mg once weekly.<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mounjaro\/dosage#mounjaro-dosage-chart-for-adults\"> <span style=\"font-weight: 400;\">Mounjaro dosage<\/span><\/a><span style=\"font-weight: 400;\"> begins at 2.5 mg injected once weekly and has an upper limit of 15 mg injected once weekly.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Not everyone reaches the maximum dosage, as many healthcare providers prefer to keep patients at the lowest effective dose for their needs. It is essential to work with your healthcare provider to determine whether you should decrease the dosage to a maintenance level after reaching a healthy weight.<\/span><\/p>\n<h2 id=\"insurance-coverage-and-cost\"><span style=\"font-weight: 400;\">Insurance coverage and cost<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The out-of-pocket costs of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ozempic-without-insurance\/\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\"> vs. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-much-does-wegovy-cost\/\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\"> vs. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/mounjaro-without-insurance\/\"><span style=\"font-weight: 400;\">Mounjaro<\/span><\/a><span style=\"font-weight: 400;\"> vary based on retail price and insurance coverage. Mounjaro and Ozempic for diabetes are more likely to be<\/span><a href=\"https:\/\/www.congress.gov\/crs-product\/IF12758\"> <span style=\"font-weight: 400;\">covered by Medicare<\/span><\/a><span style=\"font-weight: 400;\"> and private health insurance plans than Wegovy for weight loss. Still, some plans cover Wegovy with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prior-authorization\/\"><span style=\"font-weight: 400;\">prior authorization<\/span><\/a><span style=\"font-weight: 400;\"> or proof that the patient has tried other weight loss treatments first. Even when one of these drugs is covered by insurance, the copay amount varies by plan.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Without insurance or discounts, the average retail cost for a one-month supply of these medications is<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy#Price-History\"> <span style=\"font-weight: 400;\">$1,844<\/span><\/a><span style=\"font-weight: 400;\"> for Wegovy,<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ozempic-without-insurance\/\"> <span style=\"font-weight: 400;\">$1,368<\/span><\/a><span style=\"font-weight: 400;\"> for Ozempic, and<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/mounjaro-without-insurance\/\"> <span style=\"font-weight: 400;\">$1,492<\/span><\/a><span style=\"font-weight: 400;\"> for Mounjaro. SingleCare<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"> <span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\">,<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic-0-25-or-0-5-mg-dose\"> <span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\">, or<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mounjaro\"> <span style=\"font-weight: 400;\">Mounjaro<\/span><\/a><span style=\"font-weight: 400;\"> coupons may help reduce the cash price by hundreds of dollars.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th><span class=\"title\">Compare Ozempic vs. Wegovy vs. Mounjaro cost &amp; coverage<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Ozempic<\/b><\/td>\n<td><b>Wegovy<\/b><\/td>\n<td><b>Mounjaro<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicaid?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Sometimes (varies by state)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Unlikely (varies by state)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Sometimes (varies by state)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">1, 3 mL of 2 mg\/3 mL pen (4 doses)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4, 0.75 mL of 2.4 mg\/0.75 mL pens (4 doses)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4, 0.5 mL of 5 mg\/0.5 mL pens (4 doses)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$825<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$1,225<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$872<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"side-effects-and-considerations\"><span style=\"font-weight: 400;\">Side effects and considerations\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ozempic, Wegovy, and Mounjaro share similar side effects, but Dr. Odogwu says side effect frequency is lower with tirzepatide than semaglutide.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/mounjaro-vs-ozempic\/#common-side-effects-of-mounjaro-vs-ozempic\"> <span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> for all three are gastrointestinal issues, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tirzepatide-vs-semaglutide\/#tirzepatide-vs-semaglutide-side-effects\"> <span style=\"font-weight: 400;\">possible side effects<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Indigestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bloating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Injection site reactions<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.singlecare.com\/conditions\/low-blood-sugar-symptoms\"><span style=\"font-weight: 400;\">Hypoglycemia<\/span><\/a><span style=\"font-weight: 400;\">, or low blood sugar, is a serious side effect of all three drugs and warrants urgent medical attention.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Side effects vary by drug and dosage, and this is not a complete list of side effects. Higher doses are associated with increased incidence and severity of side effects. It\u2019s important to consult your healthcare provider if you experience severe side effects after starting one of these medications.<\/span><\/p>\n<h2 id=\"making-informed-decisions\"><span style=\"font-weight: 400;\">Making informed decisions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ozempic, Wegovy, and Mounjaro are similar drugs, but they\u2019re not identical. Ozempic and Wegovy both contain semaglutide, but they\u2019re approved for different uses: diabetes treatment and weight loss, respectively. Ozempic and Mounjaro have different active ingredients but share the same approved uses: blood sugar management in Type 2 diabetes.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cAlthough you can find pretty helpful information online, I do recommend to still get lab work and discuss with your provider about which option is best for you, since they will be able to take into account factors including other health conditions, medications, and insurance coverage,\u201d says Landetta.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ultimately, consulting with a prescribing healthcare provider ensures that you are receiving the best treatment for your weight loss goals and circumstances, including your insurance coverage. And if you\u2019re struggling to navigate the costs of these expensive injectable drugs, a healthcare provider can offer more affordable alternatives or point you toward <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/save-on-my-prescriptions-discounts\/\"><span style=\"font-weight: 400;\">ways to save<\/span><\/a><span style=\"font-weight: 400;\"> with copay assistance programs or drug manufacturer discount offerings.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you have Type 2 diabetes or obesity, you have probably heard about these once-weekly injections used to treat one or both conditions: Ozempic, Wegovy, and Mounjaro. These brand-name medications belong to different, but overlapping drug classes and work similarly to stimulate insulin production, resulting in lower blood sugar and reduced appetite. Ozempic and Mounjaro [&hellip;]<\/p>\n","protected":false},"author":137,"featured_media":632355,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[9825],"coauthors":[20942],"class_list":["post-632354","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Ozempic vs. Wegovy vs. Mounjaro: What\u2019s the difference?<\/title>\n<meta name=\"description\" content=\"Compare Ozempic, Wegovy, and Mounjaro for diabetes and weight loss. 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