{"id":632359,"date":"2025-05-27T11:32:29","date_gmt":"2025-05-27T15:32:29","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632359"},"modified":"2026-01-28T14:12:34","modified_gmt":"2026-01-28T19:12:34","slug":"xarelto-vs-warfarin","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/xarelto-vs-warfarin\/","title":{"rendered":"Xarelto vs. warfarin: Uses, cost, coverage, and side effects"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/xarelto\/what-is\"><span style=\"font-weight: 400;\">Xarelto<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\/what-is\"><span style=\"font-weight: 400;\">warfarin<\/span><\/a><span style=\"font-weight: 400;\"> are two prescription blood thinners that are used to prevent and treat blood clotting disorders. Xarelto is a brand-name medication, while warfarin is a generic. While they are used for similar conditions, Xarelto and warfarin work differently. Xarelto belongs to a class of drugs called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/factor-xa-inhibitors\"><span style=\"font-weight: 400;\">factor Xa inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> and works by blocking factor Xa\u2014a protein in the blood\u2014to prevent the formation of blood clots. Warfarin is a vitamin K antagonist that stops the production of clotting factors\u2014or proteins involved in blood clotting. This slows down the body\u2019s ability to form blood clots. Although both drugs are known as anticoagulants, or blood thinners, they have some major differences. In this article, we\u2019ll cover the main differences between Xarelto and warfarin.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-xarelto-vs-warfarin-key-differences\">Compare Xarelto vs. warfarin key differences<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Warfarin<\/b><\/td>\n<td><b>Xarelto<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Vitamin K antagonist<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Factor Xa inhibitor<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Generic<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic\/brand name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Coumadin, Jantoven<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Rivaroxaban<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Tablet<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Tablet, oral suspension<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies depending on INR blood test results<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10 mg to 20 mg once daily or 2.5 mg twice daily<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"conditions-treated-by-xarelto-and-warfarin\"><span style=\"font-weight: 400;\">Conditions treated by Xarelto and warfarin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Xarelto and warfarin have overlapping indications, however, Xarelto may be prescribed for other conditions as well.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Xarleto is FDA approved to:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lower the risk of stroke and embolism (blockage in a blood vessel) in patients with nonvalvular atrial fibrillation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/deep-vein-thrombosis-treatment-and-medications\"><span style=\"font-weight: 400;\">deep vein thrombosis (DVT)<\/span><\/a><span style=\"font-weight: 400;\"> and pulmonary embolism (PE)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reduce the risk of repeat DVT and PE following initial therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prevent DVT, which can lead to PE in patients having knee or hip replacement surgery<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prevent venous thromboembolism (VTE) in patients with an acute medical illness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lower the risk of major cardiovascular events, such as heart attack or stroke, in patients with coronary artery disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reduce the risk of major clotting events in patients with peripheral artery disease, such as after recent lower extremity revascularization<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treat VTE and reduce the risk of repeat VTE in children less than 18 years of age<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prevent VTE in children ages 2 years and older with congenital heart disease who have had a surgery called the Fontan procedure<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Warfarin is FDA approved to:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treat and prevent DVT and PE<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treat and prevent complications from atrial fibrillation and cardiac valve replacement<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reduce the risk of death, repeat heart attack, and clotting events after a heart attack<\/span><\/li>\n<\/ul>\n<h2 id=\"is-xarelto-better-than-warfarin\"><span style=\"font-weight: 400;\">Is Xarelto better than warfarin?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Xarelto and warfarin are both considered safe and effective medications for their respective indications. However, direct-acting oral anticoagulants (DOACs), such as Xarelto, are <\/span><a href=\"https:\/\/www.health.harvard.edu\/heart-health\/choosing-the-most-beneficial-blood-thinner\"><span style=\"font-weight: 400;\">usually preferred<\/span><\/a><span style=\"font-weight: 400;\"> over warfarin for most people with atrial fibrillation, DVT, or PE. This is because DOACs don\u2019t require frequent blood test monitoring, have fewer interactions, and have consistent dosing schedules.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In a <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10149967\/\"><span style=\"font-weight: 400;\">2023 meta-analysis<\/span><\/a><span style=\"font-weight: 400;\"> published in <\/span><i><span style=\"font-weight: 400;\">Frontiers in Surgery<\/span><\/i><span style=\"font-weight: 400;\">, researchers evaluated the safety and efficacy of Xarelto vs. warfarin for VTE. They found that Xarelto significantly reduced the incidence of VTE compared to warfarin. Xarelto also reduced nonmajor and major bleeding. There was no difference in all-cause mortality between the rivaroxaban group and warfarin group.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35252386\/\"><span style=\"font-weight: 400;\">Another clinical trial<\/span><\/a><span style=\"font-weight: 400;\"> published in <\/span><i><span style=\"font-weight: 400;\">Frontiers in Cardiovascular Medicine<\/span><\/i><span style=\"font-weight: 400;\"> found that Xarelto was non-inferior, or had similar efficacy, to warfarin when used to prevent stroke and embolism in patients with non-valvular atrial fibrillation with high bleeding risk. However, Xarelto was more effective in reducing fatal bleeding and bleeding in critical organs.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">With numerous <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticoagulants\"><span style=\"font-weight: 400;\">anticoagulants<\/span><\/a><span style=\"font-weight: 400;\"> available on the market, it can be challenging to determine which one works best for you. Results can also vary from person to person. Therefore, it is a good idea to consult with a doctor, who can discuss whether Xarelto vs. warfarin is best for you based on your medical history, other medical conditions, and existing medications.\u00a0<\/span><\/p>\n<h2 id=\"xarelto-vs-warfarin-insurance-coverage-and-cost-comparison\"><span style=\"font-weight: 400;\">Xarelto vs. warfarin: Insurance coverage and cost comparison<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Xarelto and warfarin are usually covered by commercial insurance and Medicare prescription drug plans, but coverage can vary by plan. The cost of each medication will also depend on the plan\u2019s <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/what-is-a-formulary\/\"><span style=\"font-weight: 400;\">drug formulary<\/span><\/a><span style=\"font-weight: 400;\">, your coverage state, and copays.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Without insurance, the average retail price of <\/span><span style=\"font-weight: 400;\">Xarelto<\/span><span style=\"font-weight: 400;\"> is $821 for 60, 2.5 mg tablets. A <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/xarelto\"><span style=\"font-weight: 400;\">SingleCare prescription discount card<\/span><\/a><span style=\"font-weight: 400;\"> can lower the price to $193. The average <\/span><span style=\"font-weight: 400;\">cost<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">warfarin<\/span><span style=\"font-weight: 400;\"> without insurance is $27 for 30, 5 mg tablets. However, a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\"><span style=\"font-weight: 400;\">SingleCare coupon<\/span><\/a><span style=\"font-weight: 400;\"> can reduce the price to as little as $4. This means <\/span><span style=\"font-weight: 400;\">warfarin<\/span><span style=\"font-weight: 400;\"> may be a more <\/span><span style=\"font-weight: 400;\">cost-effective choice<\/span><span style=\"font-weight: 400;\">. To obtain the most up-to-date information, ask your insurance provider or pharmacist about how much <\/span><span style=\"font-weight: 400;\">Xarelto<\/span><span style=\"font-weight: 400;\"> vs. <\/span><span style=\"font-weight: 400;\">warfarin<\/span><span style=\"font-weight: 400;\"> costs.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-xarelto-vs-warfarin-cost-and-coverage\">Compare Xarelto vs. warfarin cost and coverage<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Warfarin<\/b><\/td>\n<td><b>Xarelto<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicaid?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Cost without insurance<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$27 for 30, 5 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$821 for 60, 2.5 mg tablets<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost<\/b><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/xarelto\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Warfarin with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tWarfarin 5 mg (30 Tablet)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$4.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$4.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium#blog-cta\" class=\"coupon-see-all-btn\">See Warfarin prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"heading-6\"><\/h2>\n<h2 id=\"xarelto-vs-warfarin-side-effects\"><span style=\"font-weight: 400;\">Xarelto vs. warfarin side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because Xarelto and warfarin are blood thinners, their most common side effects are related to bleeding. These include unexplained bruising, nosebleeds, and bleeding gums. Other possible side effects of warfarin are fatigue, weakness, swelling, and headache. Common adverse effects of Xarelto include back pain, dizziness, and itching.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both medications can also cause serious side effects such as major or fatal bleeding. In fact, warfarin has a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">boxed warning<\/span><\/a><span style=\"font-weight: 400;\"> about its risk of severe bleeding. Other serious side effects of warfarin include tissue necrosis, calciphylaxis (a rare, but serious skin disorder), and kidney damage.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Aside from severe bleeding, other <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/xarelto-side-effects\/\"><span style=\"font-weight: 400;\">serious side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Xarelto include bleeding in the eye or around the spinal cord, thrombocytopenia (low platelet counts), agranulocytosis (low white blood cell counts), and liver problems.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As with all medications, severe allergic reactions can occur with Xarelto and warfarin. If you develop trouble breathing, hives, or swelling of your throat, face, tongue, or lips, get emergency medical help right away.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Keep in mind, this is not a complete list of side effects. To learn more, ask your healthcare professional about the side effects of Xarelto vs. warfarin.<\/span><\/p>\n<h2 id=\"warfarin-and-xarelto-drug-interactions-and-warnings\"><span style=\"font-weight: 400;\">Warfarin and Xarelto drug interactions and warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Warfarin can interact with several substances, including drugs, foods, and beverages. This is one of the reasons warfarin has fallen out of favor in recent years. Warfarin is known to interact with drugs that increase bleeding risk, certain antibiotics, some herbal products, and many other drugs. It can also interact with foods, such as green leafy vegetables and grapefruit. Combining these substances with warfarin can either increase or decrease levels of warfarin in the body. For example, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/quinolones\"><span style=\"font-weight: 400;\">quinolone antibiotics<\/span><\/a><span style=\"font-weight: 400;\">, such as ciprofloxacin or levofloxacin, can increase the levels of warfarin in your system. This can increase your risk of bleeding. On the other hand, combining warfarin with certain anti-seizure drugs, like carbamazepine, can lower the levels of warfarin in the body. This can make warfarin less effective and increase your risk of blood clots.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although Xarelto doesn\u2019t interact with as many drugs as warfarin, there are still certain drugs that you should avoid while taking it. Common drugs that may interact with Xarelto include <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">nonsteroidal anti-inflammatory drugs (NSAIDs),<\/span><\/a><span style=\"font-weight: 400;\"> certain anti-seizure drugs, some antibiotics, and St. John\u2019s wort. Similar to warfarin\u2019s drug interactions, combining Xarelto with these medications can either increase or decrease the levels of Xarelto in your system.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both Xarelto and warfarin have boxed warnings, which is the strongest warning issue by the United States Food and Drug Administration (FDA).\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Xarelto has two boxed warnings. The first is regarding its risk of clotting events if the drug is stopped too soon. The second is regarding its risk of spinal (bleeding around the spine) and epidural hematoma (bleeding around the brain).\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Warfarin has a boxed warning regarding its risk of major or fatal bleeding.\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Xarelto and warfarin have other warnings as well. Warfarin can cause harm to a fetus if taken during pregnancy. It can also cause complications in people with kidney disease. People with certain conditions can be at increased risk if they take warfarin. These include people with liver problems, infections, an indwelling catheter, moderate to severe <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/hypertension-treatments-and-medications\"><span style=\"font-weight: 400;\">high blood pressure<\/span><\/a><span style=\"font-weight: 400;\">, history of eye surgery, polycythemia vera (a type of blood cancer), vasculitis, and <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">diabetes<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Healthcare providers typically only prescribe Xarelto during pregnancy if the benefits outweigh the risks as taking the drug can increase the risk of bleeding during pregnancy and emergency delivery. Otherwise, Xarelto usually isn\u2019t prescribed for people with prosthetic heart valves or those with a condition called triple-positive antiphospholipid syndrome.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Xarelto and warfarin are two prescription blood thinners that are used to prevent and treat blood clotting disorders. Xarelto is a brand-name medication, while warfarin is a generic. While they are used for similar conditions, Xarelto and warfarin work differently. Xarelto belongs to a class of drugs called factor Xa inhibitors and works by blocking [&hellip;]<\/p>\n","protected":false},"author":87,"featured_media":632360,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[15103,4350],"coauthors":[20969],"class_list":["post-632359","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-drug-pricing","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Xarelto vs. warfarin: Key differences in safety, dosing, cost, and drug interactions<\/title>\n<meta name=\"description\" content=\"Compare the safety, cost, and coverage of Xarelto vs. warfarin to find out which blood thinner may be the better fit for your condition.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/xarelto-vs-warfarin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Xarelto vs. warfarin: Uses, cost, coverage, and side effects\" \/>\n<meta property=\"og:description\" content=\"Compare the safety, cost, and coverage of Xarelto vs. warfarin to find out which blood thinner may be the better fit for your condition.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/xarelto-vs-warfarin\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-27T15:32:29+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-28T19:12:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2025\/05\/Xarelto-vs.-warfarin.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Ashley Wong, Pharm. 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