{"id":632814,"date":"2025-07-10T10:59:08","date_gmt":"2025-07-10T14:59:08","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632814"},"modified":"2025-07-10T10:59:08","modified_gmt":"2025-07-10T14:59:08","slug":"mounjaro-vs-ozempic-cost","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/mounjaro-vs-ozempic-cost\/","title":{"rendered":"Mounjaro vs. Ozempic cost comparison"},"content":{"rendered":"

Mounjaro<\/span><\/a> (tirzepatide) and <\/span>Ozempic<\/span><\/a> (semaglutide) have both made headlines for their <\/span>weight loss effects<\/span><\/a>, but these once-weekly prescription injections are actually approved for blood sugar control in people with Type 2 diabetes. Because they\u2019re similar drugs with similar uses, some people may wonder which is more expensive. Although one may seem more expensive than the other, your out-of-pocket cost can depend on several factors, such as your location, choice of pharmacy, and insurance coverage.<\/span><\/p>\n

What\u2019s the difference between Mounjaro and Ozempic?<\/span><\/h2>\n

Mounjaro and Ozempic are both brand-name forms of different glucagon-like peptide-1 receptor agonists (<\/span>GLP-1s<\/span><\/a>). They are both administered via subcutaneous injection and have similar side effects. The main difference is their active ingredient, in addition to dosages and approved uses.<\/span><\/p>\n

Ingredients and drug classification<\/span><\/h3>\n

Mounjaro and Ozempic have different active ingredients and belong to different (but overlapping) classes of drugs.<\/span><\/p>\n

Ozempic is a brand-name form of semaglutide. As a GLP-1 receptor agonist, it activates the GLP-1 receptors, <\/span>lowering blood sugar<\/span><\/a>, suppressing appetite, and, in turn, reducing body weight.<\/span><\/p>\n

Mounjaro contains <\/span>tirzepatide<\/span><\/a>, a dual-action glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 agonist. It targets both GLP-1 and GIP receptors, which makes it <\/span>slightly more effective than Ozempic<\/span><\/a> at lowering blood sugar and suppressing appetite.\u00a0<\/span><\/p>\n

Dosage<\/span><\/h3>\n

Mounjaro and Ozempic are both once-weekly injections, but Mounjaro is prescribed in higher doses.\u00a0<\/span><\/p>\n

Mounjaro <\/span>starts with a 2.5 mg dose<\/span><\/a> injected once weekly and then increases to between 5 mg and 15 mg once weekly. <\/span>Ozempic dosage<\/span><\/a> starts at 0.25 mg once weekly and then increases to between 0.5 mg and 2 mg weekly. Healthcare providers will monitor their patients to determine whether to increase their dosage during the first few months of treatment.\u00a0<\/span><\/p>\n

Approved uses<\/span><\/h3>\n

The Food and Drug Administration (FDA) has approved both <\/span>Mounjaro<\/span><\/a> and Ozempic to help manage blood sugar levels in adults with Type 2 diabetes. They both work by stimulating insulin production and slowing digestion.<\/span><\/p>\n

Ozempic<\/span> is also FDA approved<\/span><\/a> to reduce the risk of cardiovascular problems, such as <\/span>heart attack<\/span><\/a> and stroke, in people with Type 2 diabetes and <\/span>heart disease<\/span><\/a>. In 2025, it <\/span>was also approved<\/span><\/a> to reduce the risk of worsening kidney problems, such as kidney failure, in people with Type 2 diabetes and <\/span>chronic kidney disease<\/span><\/a>.\u00a0\u00a0<\/span><\/p>\n

Both Mounjaro and Ozempic have not been FDA-approved for weight loss, so they are often used <\/span>off-label<\/span><\/a> for such. That said, there are FDA-approved weight loss drugs with the same active ingredients but different brand names: <\/span>Zepbound<\/span><\/a> (tirzepatide) and <\/span>Wegovy<\/span><\/a> (semaglutide).<\/span><\/p>\n

How much does Mounjaro cost without insurance?<\/span><\/h2>\n

The average retail price of a one-month supply of Mounjaro is <\/span>$1,493<\/span><\/a>, but that\u2019s not always what people pay. Prices fluctuate and vary by location and pharmacy. If your health insurance covers Mounjaro, you\u2019ll pay your plan\u2019s copay or coinsurance, not the retail price.<\/span><\/p>\n

For instance, some people are able to <\/span>save on Mounjaro<\/span><\/a> with financial assistance. You can also use a <\/span>SingleCare coupon<\/span><\/a> to reduce the cash price of a one-month supply of Mounjaro to $872.<\/span><\/p>\n

How much does Ozempic cost without insurance?<\/span><\/h2>\n

The average retail price of a one-month supply of Ozempic is <\/span>$1,384<\/span><\/a>, but the actual out-of-pocket costs vary by pharmacy, location, and more.<\/span><\/p>\n

There are several <\/span>ways to save on Ozempic<\/span><\/a>, even if you don\u2019t have insurance. For example, a <\/span>SingleCare coupon<\/span><\/a> can reduce the cash price to $825 for a one-month supply.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Mounjaro vs. Ozempic insurance and cost comparison<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nMounjaro<\/b><\/td>\nOzempic<\/b><\/td>\n<\/tr>\n
Typically covered by insurance?<\/b><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Typically covered by Medicare Part D?<\/b><\/td>\nSometimes<\/span><\/td>\nSometimes<\/span><\/td>\n<\/tr>\n
Quantity<\/b><\/td>\n4 prefilled injection pens<\/span><\/td>\n1 prefilled multidose pen<\/span><\/td>\n<\/tr>\n
Typical Medicare copay<\/b><\/td>\nVaries<\/span><\/td>\nVaries<\/span><\/td>\n<\/tr>\n
Cost without insurance*<\/b><\/td>\n $1,469<\/span><\/td>\n $1,368<\/span><\/td>\n<\/tr>\n
SingleCare cost*<\/b><\/td>\n $872<\/span><\/td>\n $825<\/span><\/td>\n<\/tr>\n
Savings<\/b><\/td>\nGet coupon<\/span><\/a><\/td>\nGet coupon<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
*Cost at time of publication. Drug prices fluctuate and vary by pharmacy and location.<\/span><\/h5>\n

<\/p>\n

<\/p>\n

Does insurance cover Mounjaro?<\/span><\/h2>\n

Sometimes. Insurance coverage for prescription drugs varies by each plan\u2019s policy, and brand-name GLP-1s for diabetes are less likely to be covered than generic drugs. \u201cEven with insurance, unless a patient has certain complications such as cardiovascular disease, uncontrollable diabetes on other medications, kidney disease, and\/or obesity, the medication is not likely to be covered,\u201d says <\/span>Troy Alexander-EL, MD<\/span><\/a>, a board-certified internal medicine physician and founder of Higher Level Healthcare.<\/span><\/p>\n

Still, some insurance companies do offer plans that cover Mounjaro. For instance, <\/span>United Healthcare<\/span><\/a> and <\/span>Blue Cross Blue Shield<\/span><\/a> plans typically cover Mounjaro when prescribed for blood sugar control in Type 2 diabetes. Some plans require prior authorization, so it\u2019s a good idea to check your <\/span>drug formulary<\/span><\/a> before requesting a prescription from your healthcare provider.<\/span><\/p>\n

Additionally, <\/span>Medicaid<\/span><\/a> and <\/span>Medicare<\/span><\/a> coverage are much more likely for blood sugar control with diabetes treatment than for weight loss.\u00a0<\/span><\/p>\n

Does insurance cover Ozempic?<\/span><\/h2>\n

\u201c<\/span>In my experience, generally Ozempic has better insurance coverage and may be more affordable compared to Mounjaro,\u201d says <\/span>Vandana Sheth, RDN, CDCES, FAND<\/span><\/a>, a Los Angeles-based registered dietitian nutritionist and certified diabetes educator.<\/span> \u201cHowever, coverage and costs vary based on insurance plans, formulary status, as well as pharmacy benefit manager negotiations.\u201d Like Mounjaro, <\/span>Ozempic is more likely to be covered when prescribed for an FDA-approved use\u2014diabetes treatment, cardiovascular risk reduction, and kidney failure risk reduction\u2014than for weight loss.<\/span><\/p>\n

Medicare<\/span><\/a> and <\/span>Medicaid<\/span><\/a> coverage for Ozempic also depends on the specific plan and your reason for using Ozempic. Medicare and Medicaid generally offer coverage for Ozempic when deemed medically necessary.<\/span><\/p>\n

You can check your cost and coverage for Ozempic with <\/span>this tool<\/span><\/a> from Novo Nordisk, the manufacturer of Ozempic.<\/span><\/p>\n

RELATED: <\/b>How to get Ozempic covered by insurance<\/b><\/a><\/p>\n

Bottom line<\/span><\/h2>\n

Mounjaro costs slightly more than Ozempic. However, your actual out-of-pocket costs for Mounjaro versus Ozempic depend on insurance coverage and the reason you\u2019re taking it. <\/span>SingleCare coupons<\/span><\/a> can also help you save hundreds per month on the price of <\/span>Mounjaro<\/span><\/a> or <\/span>Ozempic<\/span><\/a>.<\/span><\/p>\n

Ultimately, only a healthcare professional familiar with your health conditions, medical history, and other medications you\u2019re taking can recommend whether Mounjaro, Ozempic, or another diabetes medication or weight loss treatment is best for you.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Mounjaro (tirzepatide) and Ozempic (semaglutide) have both made headlines for their weight loss effects, but these once-weekly prescription injections are actually approved for blood sugar control in people with Type 2 diabetes. Because they\u2019re similar drugs with similar uses, some people may wonder which is more expensive. Although one may seem more expensive than the […]<\/p>\n","protected":false},"author":149,"featured_media":632816,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[10298,15103,21067],"coauthors":[20942],"class_list":["post-632814","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-diabetes","tag-drug-pricing","tag-glp-1-drugs","wpautop"],"acf":[],"yoast_head":"\nMounjaro vs. Ozempic cost comparison<\/title>\n<meta name=\"description\" content=\"The cost of Mounjaro is slightly higher than the cost of Ozempic, but the price you pay depends on various factors, such as your location, pharmacy, and insurance.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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