{"id":632894,"date":"2025-07-17T11:57:52","date_gmt":"2025-07-17T15:57:52","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=632894"},"modified":"2025-07-17T11:59:22","modified_gmt":"2025-07-17T15:59:22","slug":"mounjaro-vs-farxiga-differences-and-similarities-explained","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/mounjaro-vs-farxiga-differences-and-similarities-explained\/","title":{"rendered":"Mounjaro vs. Farxiga: Differences and similarities explained"},"content":{"rendered":"

Your healthcare provider might prescribe <\/span>Mounjaro<\/span><\/a> or <\/span>Farxiga<\/span><\/a> to help manage Type 2 diabetes, especially when diet and exercise aren\u2019t enough. Both medications help control blood sugar and may also support weight loss, reducing <\/span>serious risks<\/span><\/a> related to diabetes. Although Mounjaro and Farxiga treat similar problems, they belong to different drug classes and work in different ways.\u00a0<\/span><\/p>\n

Key differences between Mounjaro and Farxiga<\/span><\/h2>\n

Mounjaro contains tirzepatide, which targets both GIP (glucose-dependent insulinotropic polypeptide) and <\/span>GLP-1 (glucagon-like peptide-1) receptors<\/span><\/a>, helping you release more insulin after eating and keeping you fuller for longer. Farxiga\u2019s active ingredient is dapagliflozin, which belongs to the <\/span>SGLT2 (sodium-glucose cotransporter-2) inhibitor<\/span><\/a> drug class and works by helping the kidneys remove excess glucose through urine. These medications can vary in side effects, how they\u2019re taken, and overall cost.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Compare Mounjaro vs. Farxiga key differences<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nMounjaro<\/b><\/td>\nFarxiga<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nDual GIP and GLP-1 agonist<\/span><\/td>\nSGLT2 inhibitor<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nBrand name only<\/span><\/td>\nBrand and generic version available<\/span><\/td>\n<\/tr>\n
What is the generic name?<\/b><\/p>\n

Or<\/b><\/p>\n

What is the brand name?<\/b><\/td>\n

Tirzepatide<\/span><\/td>\nDapagliflozin<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nSubcutaneous injection<\/span><\/td>\nOral tablet<\/span><\/td>\n<\/tr>\n
What is the standard dosage?<\/b><\/td>\n2.5 mg injected under the skin once weekly for 4 weeks. If needed, the dosage may be increased to 5 mg once weekly. The dosage can then be increased by 2.5 mg every 4 weeks, up to a maximum of 15 mg once weekly.<\/span><\/td>\n5 mg by mouth once daily, with or without food. If well tolerated, the dose may be increased to 10 mg once daily.<\/span><\/td>\n<\/tr>\n
How long is the typical treatment?<\/b><\/td>\nLong-term<\/span><\/td>\nLong-term<\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nAdults<\/span><\/td>\nAdults and children 10 and older<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Mounjaro and Farxiga are approved by the Food and Drug Administration (FDA) to manage <\/span>Type 2 diabetes<\/span><\/a> mellitus. However, <\/span>Mounjaro<\/span><\/a> is only approved to treat adults, while <\/span>Farxiga<\/span><\/a> is approved to treat adults and children aged 10 and older with Type 2 diabetes.<\/span><\/p>\n

Unlike Mounjaro, Farxiga is also FDA approved to protect the kidneys in people with known kidney problems and lower the risk of hospitalization in people with heart failure. In addition, Farxiga can help reduce the risk of complications in people with Type 2 diabetes and heart disease or risk factors for heart disease, such as high blood pressure and high cholesterol.<\/span><\/p>\n

Both medications may also help promote <\/span>weight loss<\/span><\/a>, especially in people with diabetes or obesity. In some cases, a healthcare provider may prescribe these medications for weight loss, even in people without diabetes. However, Mounjaro is more likely to be prescribed off-label for this purpose.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n
\n

Compare Mounjaro vs. Farxiga conditions treated<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Condition<\/b><\/td>\nMounjaro<\/b><\/td>\nFarxiga<\/b><\/td>\n<\/tr>\n
Type 2 diabetes<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Reduce the risk of reduced kidney function, kidney failure, death from heart problems, and hospitalization in adults with chronic kidney disease<\/span><\/td>\nNo<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Reduce the risk of death from heart problems, hospital stays for heart failure, and urgent visits in adults with heart failure<\/span><\/td>\nNo<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Reduce the risk of hospital visits for heart failure in adults with Type 2 diabetes and either existing cardiovascular disease or multiple risk factors for heart problems<\/span><\/td>\nNo<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Weight loss\u00a0<\/span><\/td>\nOff-label<\/span><\/td>\nOff-label<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Which is the best Type 2 diabetes medication?<\/span><\/h3>\n

Mounjaro and Farxiga are both effective for managing blood sugar levels. One study found no major difference between the treatments in helping people reach certain health goals. <\/span>Around 30%<\/span><\/a> of people with Type 2 diabetes who started either Farxiga or a GLP-1 medicine were able to lower their blood sugar, body weight, and blood pressure at the same time.\u00a0<\/span><\/p>\n

However, <\/span>one meta-analysis<\/span><\/a> of several clinical trials comparing Mounjaro to SGLT2 inhibitors showed that Mounjaro was the most effective medicine for lowering blood sugar and helping people lose weight. The highest dose of Mounjaro lowered blood sugar by around 2% and resulted in nearly 9 kg (approximately 20 pounds) more weight loss than no treatment. The SGLT2 drugs like <\/span>Farxiga and Jardiance<\/span><\/a> were best at lowering blood pressure, making them a good choice for people with both diabetes and high blood pressure.<\/span><\/p>\n

If you prefer a once-weekly injection over a daily oral tablet and are struggling with weight management, you might opt for Mounjaro over Farxiga. If you have kidney problems or heart failure in addition to diabetes, you might be recommended a drug like Farxiga. It\u2019s best to consult a healthcare provider to determine the best medication for your needs.\u00a0<\/span><\/p>\n

Mounjaro vs. Farxiga: Insurance coverage and cost comparison<\/span><\/h2>\n

Mounjaro and Farxiga are brand-name prescription drugs. Insurance plans and Medicare often cover these medications, but coverage and copay costs can be different depending on the plan. Farxiga is available as a <\/span>generic<\/span><\/a>, which may make it more likely to be covered by insurance than Mounjaro.<\/span><\/p>\n

With no insurance, retail prices for these drugs can vary, although Farxiga is generally less expensive than Mounjaro. For example, a one-month supply of Mounjaro can cost about $1,475 out of pocket. Farxiga can cost around $864, although the exact price depends on the dosage and pharmacy chosen. Generic prices may be considerably <\/span>less costly<\/span><\/a>.<\/span><\/p>\n

SingleCare offers coupons for both <\/span>Mounjaro<\/span><\/a> and <\/span>Farxiga<\/span><\/a> that can significantly lower the price at the pharmacy. It can be helpful to compare coupon prices at different pharmacies before choosing where to fill the prescription.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n
\n

Compare Mounjaro vs. Farxiga cost and coverage<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nMounjaro<\/b><\/td>\nFarxiga<\/b><\/td>\n<\/tr>\n
Typically covered by insurance?<\/b><\/td>\nSome plans may provide coverage, although it varies\u00a0\u00a0<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Typically covered by Medicare Part D?<\/b><\/td>\nSome plans may provide coverage, although it varies\u00a0\u00a0<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Typically covered by Medicaid?<\/b><\/td>\nVaries by state Medicaid program<\/span><\/td>\nVaries by state Medicaid program<\/span><\/td>\n<\/tr>\n
Quantity<\/b><\/td>\n4 prefilled injection pens<\/span><\/td>\n30, 10 mg tablets<\/span><\/td>\n<\/tr>\n
SingleCare cost*<\/b><\/td>\n$872<\/span><\/a><\/td>\n$362<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
*Cost at time of publication. Drug prices fluctuate and vary by pharmacy.<\/span><\/h5>\n

Farxiga vs. Mounjaro side effects<\/span><\/h2>\n

Because they work differently in the body, Mounjaro and Farxiga can cause different types of side effects. The most <\/span>common side effects of Mounjaro<\/span><\/a> include:<\/span><\/p>\n