{"id":633072,"date":"2025-08-06T13:17:36","date_gmt":"2025-08-06T17:17:36","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633072"},"modified":"2025-10-16T15:17:14","modified_gmt":"2025-10-16T19:17:14","slug":"best-statin-for-anxiety","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/best-statin-for-anxiety\/","title":{"rendered":"Best statin for anxiety"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/drug-classes\/statins\"><span style=\"font-weight: 400;\">Statins<\/span><\/a><span style=\"font-weight: 400;\"> are a class of drugs that help lower cholesterol levels and reduce the risk of heart attack or stroke. Also called HMG-CoA reductase inhibitors, statins work by reducing the production of cholesterol in the liver and by helping the body to absorb cholesterol stuck to the interior walls of blood vessels. Several FDA-approved statin medications can be prescribed for <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/high-cholesterol-causes\"><span style=\"font-weight: 400;\">high cholesterol<\/span><\/a><span style=\"font-weight: 400;\">. Most of them are well-tolerated and don\u2019t typically cause side effects like anxiety. In the rare event that a statin seems to cause anxiety or panic attacks, your healthcare provider can recommend another statin or a different type of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/high-cholesterol-treatment-and-medications\"><span style=\"font-weight: 400;\">cholesterol-lowering medication<\/span><\/a><span style=\"font-weight: 400;\">. Statins aren\u2019t psychiatric drugs, so they don\u2019t treat anxiety in people who already experience it.\u00a0<\/span><\/p>\n<h2 id=\"can-statins-cause-anxiety-and-panic-attacks\"><span style=\"font-weight: 400;\">Can statins cause anxiety and panic attacks?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Scientific studies have found no major connection between statins and anxiety or panic attacks, but that doesn\u2019t mean they\u2019re not related.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A study published in <\/span><i><span style=\"font-weight: 400;\">Psychopharmacology<\/span><\/i><span style=\"font-weight: 400;\"> in 2022 saw a slight increase in self-reported anxiety levels among people who had just started taking simvastatin (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zocor\"><span style=\"font-weight: 400;\">Zocor<\/span><\/a><span style=\"font-weight: 400;\">). The uptick in anxiety was temporary, and the study authors suggest that simvastatin may have a similar effect on anxiety as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">antidepressants<\/span><\/a><span style=\"font-weight: 400;\">, which sometimes worsen anxiety symptoms for a short period of time.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Despite a lack of large-scale scientific evidence, there are anecdotal reports of statin drugs causing or increasing anxiety in some individuals. \u201cEveryone\u2019s body and brain chemistry are different,\u201d says <\/span><a href=\"https:\/\/www.mindpath.com\/resource\/leadership\/anoop-singh\/\"><span style=\"font-weight: 400;\">Anoop Singh<\/span><\/a><span style=\"font-weight: 400;\">, MD, a board-certified psychiatrist and Regional Medical Director with Mindpath Health. \u201cIn rare cases, changes in sleep, mood, or energy might occur [with statins]\u2014sometimes as a result of how the medication affects brain chemistry.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Several individual cases of statins causing anxiety were documented in a <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5005588\/\"><span style=\"font-weight: 400;\">2015 report<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">After starting 20 mg of atorvastatin (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lipitor\"><span style=\"font-weight: 400;\">Lipitor<\/span><\/a><span style=\"font-weight: 400;\">), a male teenager experienced side effects like anxiety, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-causes\"><span style=\"font-weight: 400;\">depression<\/span><\/a><span style=\"font-weight: 400;\">, cognitive impairment, and violent nightmares. His symptoms rapidly improved after he stopped taking atorvastatin. When he began taking statins again, all of the psychiatric side effects reappeared, and he took his own life two weeks later.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A man in his 30s experienced anxiety and violent thoughts after his atorvastatin dose increased from 10 mg to 20 mg to 40 mg. His psychiatric side effects went away within two weeks of his last dose of atorvastatin.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Within five days of starting 80 mg simvastatin, a man in his 40s began experiencing numerous psychiatric symptoms, including anxiety, depression, and irritability. He took his own life nine months later.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The 2015 report explored a total of 12 cases where statins may have caused psychiatric side effects, and anxiety was reported in only three of those cases (25%). The fact that two of the three individuals who experienced statin-related anxiety eventually died by suicide highlights just how serious psychiatric side effects can be, even if they\u2019re rare.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The study authors believe a previous history of mental health conditions may make certain people more likely to experience anxiety, depression, and other mood or cognitive changes while taking statins. It\u2019s important to tell your healthcare provider if you\u2019ve ever had mental health concerns, including generalized anxiety disorder and major depressive disorder, so they can choose the safest cholesterol-lowering drugs for you.\u00a0<\/span><\/p>\n<h2 id=\"top-recommended-statins-for-people-with-anxiety\"><span style=\"font-weight: 400;\">Top recommended statins for people with anxiety<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some statins may be less likely to cause or increase anxiety due to the way they interact with the blood-brain barrier. This is a protective layer of tissue around the brain that keeps infectious substances out while allowing nutrients and other important substances in. Molecules surrounded by lipids have an easier time passing through the blood-brain barrier. These are called lipophilic molecules.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some health experts believe lipophilic statins may be more likely to cause anxiety in sensitive individuals because of their ability to easily access and interact with the brain. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34095267\/\"><span style=\"font-weight: 400;\">Lipophilic statins include<\/span><\/a><span style=\"font-weight: 400;\"> simvastatin, fluvastatin, pitavastatin, lovastatin, and atorvastatin.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIn theory, some statins that can cross the blood-brain barrier may affect the processing of certain chemicals involved in mood regulation,\u201d says <\/span><a href=\"https:\/\/newwatersrecovery.com\/contributor\/dr-harold-hong-md\/\"><span style=\"font-weight: 400;\">Harold Hong<\/span><\/a><span style=\"font-weight: 400;\">, MD, a board-certified psychiatrist and Medical Director at New Waters Recovery. \u201cOther statins, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/pravastatin-sodium\"><span style=\"font-weight: 400;\">pravastatin<\/span><\/a><span style=\"font-weight: 400;\"> or rosuvastatin (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/crestor\"><span style=\"font-weight: 400;\">Crestor<\/span><\/a><span style=\"font-weight: 400;\">), tend to remain in the bloodstream for a more extended period and may be less likely to affect mood. That said, not everyone reacts the same way, and these kinds of side effects are still relatively rare.\u201d\u00a0<\/span><\/p>\n<h3 id=\"pravastatin\"><span style=\"font-weight: 400;\">Pravastatin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Pravastatin (formerly available as name-brand Pravachol) may be one of the best statins not to cause anxiety because it doesn\u2019t easily pass the blood-brain barrier. <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/019898s062lbl.pdf\"><span style=\"font-weight: 400;\">Clinical trials<\/span><\/a><span style=\"font-weight: 400;\"> support the idea that anxiety and depression are rare side effects of pravastatin. Sleep disturbances were a little more common among study participants.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The main disadvantage of pravastatin is that it\u2019s <\/span><a href=\"https:\/\/www.uspharmacist.com\/article\/considerations-in-the-approach-to-appropriate-statin-selection\"><span style=\"font-weight: 400;\">not quite as aggressive<\/span><\/a><span style=\"font-weight: 400;\"> at lowering cholesterol as other statins. If your healthcare provider wants you to lower your LDL cholesterol by 50% or more, they may recommend a more powerful statin like rosuvastatin because pravastatin won\u2019t decrease LDL into the goal range.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/when-to-take-statins\/\"><span style=\"font-weight: 400;\">Like most statins<\/span><\/a><span style=\"font-weight: 400;\">, pravastatin should be taken in the evening. It\u2019s generally well tolerated and is <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3920796\/\"><span style=\"font-weight: 400;\">less likely<\/span><\/a><span style=\"font-weight: 400;\"> to carry a risk of myalgia (muscle pain) compared to other statins. Pravastatin is also associated with fewer drug interactions, especially with drugs known as CYP450 inhibitors or inducers.\u00a0<\/span><\/p>\n<h3 id=\"rosuvastatin-crestor\"><span style=\"font-weight: 400;\">Rosuvastatin (Crestor)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Rosuvastatin (generic Crestor) is the only other statin aside from pravastatin that doesn\u2019t cross the blood-brain barrier. Anxiety <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2023\/021366s043s044lbl.pdf\"><span style=\"font-weight: 400;\">wasn\u2019t recorded<\/span><\/a><span style=\"font-weight: 400;\"> in clinical studies, but depression, nightmares, and insomnia occurred in rare cases.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Rosuvastatin is one of just two statins that can be used to reduce cholesterol by 50% or more (also known as high-intensity therapy). If you need to lower your cholesterol by less than 30%, your healthcare provider may prescribe a less powerful statin like pravastatin.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although some statins must be taken at night or in the morning, rosuvastatin can be taken at any time of day, with or without food, and it\u2019s associated with fewer CYP450 drug interactions. Muscle weakness (myopathy) is <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8818528\/\"><span style=\"font-weight: 400;\">less common<\/span><\/a><span style=\"font-weight: 400;\"> with rosuvastatin, occurring in about 11% of individuals compared to a 50% incident rate with simvastatin.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"statins-comparison-chart\"><span class=\"title\">Statins comparison chart<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Name<\/b><\/td>\n<td><b>Pros<\/b><\/td>\n<td><b>Cons<\/b><\/td>\n<td><b>Cost with SingleCare*<\/b><\/td>\n<td><b>Savings<\/b><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/pitavastatin-calcium\/what-is\"><b>Pravastatin<\/b><\/a><b> (formerly Pravachol)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Doesn\u2019t cross blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Less likely to interact with certain medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Less likely to cause muscle pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Good for low to moderate reduction in cholesterol<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety rarely reported in clinical trials<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression and sleep disturbances may occur in rare cases<\/span><\/li>\n<\/ul>\n<\/td>\n<td><span style=\"font-weight: 400;\">$17 per <a href=\"https:\/\/www.singlecare.com\/prescription\/pravastatin-sodium\/dosage\">90, 40 mg tablets<\/a> of generic pravastatin<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/pravastatin-sodium\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/rosuvastatin-calcium\/what-is\"><b>Rosuvastatin <\/b><\/a><b>(Crestor)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Doesn\u2019t cross blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Less likely to interact with certain medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Less likely to cause muscle weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Great for significant reduction in cholesterol<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression, insomnia, and nightmares may occur in rare cases<\/span><\/li>\n<\/ul>\n<\/td>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/rosuvastatin-calcium\/dosage\"><span style=\"font-weight: 400;\">$8 per 30, 10 mg tablets of generic rosuvastatin<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/rosuvastatin-calcium\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/atorvastatin-calcium\/what-is\"><b>Atorvastatin<\/b><\/a><b> (Lipitor)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Great for significant reduction in cholesterol<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Can cross the blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Interacts with CYP450 inhibitors and inducers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression can occur in rare cases<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">At least two known suicides related to atorvastatin<\/span><\/li>\n<\/ul>\n<\/td>\n<td><span style=\"font-weight: 400;\">$8 per 30, 40 mg tablets of generic atorvastatin<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/atorvastatin-calcium\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/fluvastatin-sodium\/what-is\"><b>Fluvastatin<\/b><\/a><b> (Lescol)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Good for low to moderate reduction in cholesterol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lowest incidence of muscle weakness of all statins<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Can cross the blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Interacts with CYP450 inhibitors and inducers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety, insomnia, depression, and psychic disturbances reported in rare cases<\/span><\/li>\n<\/ul>\n<\/td>\n<td><span style=\"font-weight: 400;\">$45 per 30, 20 mg capsules of generic fluvastatin<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/fluvastatin-sodium\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/simvastatin\/what-is\"><b>Simvastatin<\/b><\/a><b> (Zocor)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Good for low to moderate reduction in cholesterol<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Can cross the blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Interacts with CYP450 inhibitors and inducers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle weakness occurs in about 50% of individuals<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">At least one known suicide related to simvastatin<\/span><\/li>\n<\/ul>\n<\/td>\n<td><span style=\"font-weight: 400;\">$7 per 90, 20 mg tablets of generic simvastatin<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/simvastatin\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/lovastatin\/what-is\"><b>Lovastatin<\/b><\/a><b> (Mevacor)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Good for low to moderate reduction in cholesterol<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Can cross the blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Interacts with CYP450 inhibitors and inducers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Should be taken with food<\/span><\/li>\n<\/ul>\n<\/td>\n<td><span style=\"font-weight: 400;\">$15 per 90, 20 mg tablets of generic lovastatin<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lovastatin\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/pitavastatin-calcium\/what-is\"><b>Pitavastatin<\/b><\/a><b> (Livalo)<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Good for low to moderate reduction in cholesterol<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Can cross the blood-brain barrier<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Interacts with CYP450 inhibitors and inducers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">May cause depression, insomnia, or cognitive impairment in rare cases<\/span><\/li>\n<\/ul>\n<\/td>\n<td><span style=\"font-weight: 400;\">$45 per 30, 2 mg tablets of generic pitavastatin<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/pitavastatin-calcium\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><span style=\"font-weight: 400;\">*Cost at time of publication. Drug prices fluctuate and vary by pharmacy and location.\u00a0<\/span><\/h5>\n<h2 id=\"special-considerations-for-people-with-anxiety-taking-statins\"><span style=\"font-weight: 400;\">Special considerations for people with anxiety taking statins<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When discussing cholesterol treatment options with your healthcare provider, it\u2019s important to mention that you have anxiety or a family history of anxiety. Even if your anxiety is well-controlled, some statins could cause an increase in your level of anxiety. This is rare and can be temporary. However, in some cases, the psychological side effects of statins can be so severe as to be life-threatening. Tell your healthcare provider right away if you experience anxiety or other unwanted side effects while taking statins. The national suicide hotline in the U.S. is called the<\/span><b> 988 Suicide &amp; Crisis Lifeline<\/b><span style=\"font-weight: 400;\">. Individuals can call or text 988 24 hours a day, 7 days a week.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cSometimes, switching to a different statin\u2014especially one that does not enter the brain as much\u2014can help. There are also non-statin options, like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ezetimibe\"><span style=\"font-weight: 400;\">ezetimibe<\/span><\/a><span style=\"font-weight: 400;\"> (Zetia) or <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/pcsk9-inhibitors\"><span style=\"font-weight: 400;\">PCSK9 inhibitors<\/span><\/a><span style=\"font-weight: 400;\">, that lower cholesterol through different mechanisms and may be better tolerated,\u201d Dr. Hong says.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Singh agrees with Dr. Hong\u2019s advice. He adds that short-term anxiety treatments might help people adjust to the medication. \u201cTherapy, relaxation techniques, or even temporary medication, if absolutely necessary, can help patients through the initial adjustment periods. Most importantly, this should be a shared decision between you, your primary doctor, and possibly a cardiologist or psychiatrist, depending on the situation.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Statins are a class of drugs that help lower cholesterol levels and reduce the risk of heart attack or stroke. Also called HMG-CoA reductase inhibitors, statins work by reducing the production of cholesterol in the liver and by helping the body to absorb cholesterol stuck to the interior walls of blood vessels. Several FDA-approved statin [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":633073,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9777,20952],"coauthors":[21074],"class_list":["post-633072","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-anxiety","tag-high-cholesterol","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Best statin for anxiety<\/title>\n<meta name=\"description\" content=\"Although more research is needed to determine the best statin for anxiety, pravastatin and rosuvastatin (Crestor) may be less likely to cause anxiety symptoms.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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