{"id":633151,"date":"2025-08-19T09:30:34","date_gmt":"2025-08-19T13:30:34","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633151"},"modified":"2025-08-12T10:48:52","modified_gmt":"2025-08-12T14:48:52","slug":"uncommon-side-effects-of-myrbetriq","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/uncommon-side-effects-of-myrbetriq\/","title":{"rendered":"5 uncommon side effects of Myrbetriq"},"content":{"rendered":"

Myrbetriq (mirabegron)<\/span><\/a> is a brand-name medication used to treat overactive bladder (OAB) in adults. It\u2019s a beta-3 adrenergic agonist that relaxes the bladder muscle and allows the bladder to comfortably hold more urine. This helps you make fewer trips to the bathroom and reduces urinary frequency, urgency, and leakage.\u00a0<\/span><\/p>\n

If you\u2019ve been prescribed Myrbetriq, your healthcare provider may have warned you about the drug\u2019s more common side effects: increased blood pressure, dry mouth, cold-like symptoms, urinary tract infection (UTI), and headache. However, a small number of people taking Myrbetriq have reported a variety of other symptoms, too. Though these aren\u2019t common, they are possible reactions to this medication. Here\u2019s what to know.<\/span><\/p>\n\t\t

\n\t\t\t

Save up to 80% on Myrbetriq with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tMyrbetriq 50 mg (30 tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"CVS\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$189.16\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Publix\"\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$303.08\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Myrbetriq prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

What are the uncommon side effects of Myrbetriq?<\/span><\/h2>\n

When prescribing a new medication to one of their patients, healthcare professionals usually explain what a person can expect as far as symptom relief and possible side effects, but they can\u2019t review <\/span>every <\/span><\/i>possible adverse reaction to a drug. Instead, they usually focus on the most commonly reported side effects or the ones you personally may be at a higher risk of experiencing based on your medical history.<\/span><\/p>\n

That means you might be prepared for Myrbetriq side effects like a headache or stuffy nose, but not for symptoms like heartburn or palpitations. Though these serious side effects are considered uncommon\u2014they affect 2% or fewer of people taking the drug\u2014they\u2019re still worth knowing about.<\/span><\/p>\n

Upset stomach<\/span><\/h3>\n

There are a few different gastrointestinal symptoms you might experience on Myrbetriq. In clinical trials, with less than 2% of people taking it reporting constipation, diarrhea, and abdominal pain. The prescribing information for Myrbetriq also indicates that fewer than 1% of people have reported heartburn, bloating, and stomach inflammation.\u00a0<\/span><\/p>\n

It\u2019s not clear from existing studies how soon after starting Myrbetriq these GI symptoms begin or if they usually go away over time, says <\/span>Christopher Kannady<\/span><\/a>, MD, urologist at CLS Health in Texas. In general, <\/span>Myrbetriq side effects resolve on their own<\/span><\/a> as your body adjusts to the medication, but some last as long as you\u2019re taking the drug.<\/span><\/p>\n

Myrbetriq can be taken with or without food<\/span><\/a>, but taking it with food could help ease some of your GI symptoms. You can also manage temporary GI side effects with over-the-counter (OTC) medications, says Dr. Kannaday. Think: antacids for heartburn, <\/span>Imodium (loperamide)<\/span><\/a> for diarrhea, and stool softeners for <\/span>constipation<\/span><\/a>.<\/span><\/p>\n

Glaucoma\u00a0<\/span><\/h3>\n

It\u2019s technically true that Myrbetriq has been associated with rare cases of angle-closure glaucoma, but according to <\/span>Jason B. Carter<\/span><\/a>, MD, urologist and medical advisor at Aeroflow Urology, most people don\u2019t need to worry. Unless you have a history of narrow-angle glaucoma, the risk is negligible. It was reported in fewer than 1% of people, and primarily in what\u2019s called post-marketing surveillance, says Dr. Carter. (This means during the manufacturer\u2019s continued monitoring of patients after the drug is approved and being used by patients.)<\/span><\/p>\n

Even in people with other types of glaucoma, <\/span>Myrbetriq hasn\u2019t been found to cause or worsen symptoms<\/span><\/a>. However, Dr. Carter says if you experience any eye pain, blurred vision, or halos around lights while taking this drug, especially at the start of treatment, you should contact your provider right away or get immediate medical care to prevent complications.<\/span><\/p>\n

Sinus infections\u00a0<\/span><\/h3>\n

Nasopharyngitis, or inflammation of the nose and throat, occurs in 3%-4% of people taking Myrbetriq. The drug can make you feel as if you have a cold, causing a stuffy or runny nose, cough, or sore throat.\u00a0\u00a0<\/span><\/p>\n

Although sinus infections aren\u2019t considered a common side effect of Myrbetriq (they\u2019ve been reported in fewer than 1% of people), Dr. Carter says he\u2019s had some of his own patients report ongoing nasal congestion and sinus infections after starting the drug: \u201c[Myrbetriq has a] mild drying effect on mucosal surfaces, which could interfere with normal sinus drainage, especially in those with allergies or a prior history of chronic sinusitis.\u201d<\/span><\/p>\n

Sinus symptoms are usually an early side effect of treatment, Dr. Carter says, appearing in the first few months. If your symptoms are mild, he recommends treating them by drinking plenty of water, using saline rinses, and running a humidifier in your bedroom at night.\u00a0\u00a0<\/span><\/p>\n

Cardiovascular changes\u00a0<\/span><\/h3>\n

About 7%-11% of people taking Myrbetriq will experience high blood pressure or hypertension because of how the drug works. Although it targets <\/span>beta-3 receptors in the bladder<\/span><\/a>, beta-3 receptors are also found in your circulatory system. Sometimes Myrbetriq affects these receptors, causing cardiovascular side effects, says Dr. Kannady. In addition to hypertension, it may also cause <\/span>tachycardia<\/span><\/a> (high heart rate) and <\/span>heart palpitations<\/span><\/a>, though these symptoms have been reported in fewer than 2% and 1% of people, respectively\u00a0<\/span><\/p>\n

Heart rate symptoms like tachycardia and palpitations may go away after being on Myrbetriq for a few weeks, says Dr. Carter, or they can persist as long as you\u2019re taking the drug. If your symptoms are mild, follow your provider\u2019s advice about when to get in touch; they may tell you to monitor your symptoms and contact them if they don\u2019t get better in a few weeks, or they may want to hear from you right away.\u00a0<\/span><\/p>\n

You should get immediate medical care for any of the following symptoms:<\/span><\/p>\n