{"id":633169,"date":"2025-08-12T18:12:46","date_gmt":"2025-08-12T22:12:46","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633169"},"modified":"2025-08-12T18:12:46","modified_gmt":"2025-08-12T22:12:46","slug":"ajovy-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/ajovy-alternatives\/","title":{"rendered":"Ajovy alternatives: What can I take instead of Ajovy?"},"content":{"rendered":"

Migraines<\/span><\/a> are a common type of headache that affects about <\/span>39 million people<\/span><\/a> in the United States. The condition can affect anyone, including men, women, and children. While there is no cure for migraines, several <\/span>treatments<\/span><\/a> are available that can help relieve <\/span>migraine headache<\/span> symptoms.\u00a0<\/span><\/p>\n

Ajovy<\/span><\/a> (<\/span>fremanezumab<\/span>) is a <\/span>brand-name<\/span> prescription drug<\/span> used for the <\/span>preventive treatment of migraines<\/span>. It is a <\/span>monoclonal antibody<\/span> that belongs to the drug class known as <\/span>calcitonin gene-related peptide<\/span> (<\/span>CGRP<\/span>) antagonists. <\/span>Ajovy<\/span> is an injectable medication that is administered either once a month or once every three months. While it is an effective medication for many, it can cause certain <\/span>side effects<\/span> and worsen some existing medical conditions, such as <\/span>high blood pressure<\/span><\/a>. <\/span>Ajovy<\/span> is also quite costly. Therefore, it may not be right for everyone. Fortunately, there are several <\/span>Ajovy<\/span> alternatives.\u00a0<\/span><\/p>\n

What can I take instead of <\/span>Ajovy<\/span>?<\/span><\/h2>\n

Other treatments are available to treat migraines that do not improve with <\/span>Ajovy<\/span>. These <\/span>include<\/span><\/a> other <\/span>CGRP antagonists<\/span><\/a>, pain relievers, <\/span>triptans<\/span>, ergotamines, and certain beta blockers. Alternatives to <\/span>Ajovy<\/span> may be more suitable for some individuals due to their different uses, administration, dosages, <\/span>side effect<\/span> profiles, and cost.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare <\/span>Ajovy<\/span> alternatives<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Ajovy<\/span> <\/a>(<\/span>fremanezumab<\/span>)<\/span><\/td>\n$1,031 for 1, 1.5mL of 225mg\/1.5mL pen<\/span><\/td>\n$653 for 1, 1.5mL of 225mg\/1.5mL pen of <\/span>brand-name<\/span> Ajovy<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Aimovig<\/span><\/a> (<\/span>erenumab<\/span>)<\/span><\/td>\n$1,041 for 1, 1mL of 140mg\/mL pen<\/span><\/td>\n$753 for 1, 1mL of 140mg\/mL pen of <\/span>brand-name<\/span> Aimovig<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Qulipta<\/span><\/a> (<\/span>atogepant<\/span>)<\/span><\/td>\n$1,579 for 30, 60 mg tablets<\/span><\/td>\n$953 for 30, 60 mg tablets of <\/span>brand-name<\/span> Qulipta<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Emgality<\/span> <\/a>(<\/span>galcanezumab<\/span>)<\/span><\/td>\n$965 for 1, 1mL of 120mg\/mL pen<\/span><\/td>\n$605 for 1, 1mL of 120mg\/mL pen of <\/span>brand-name<\/span> Emgality<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Ubrelvy<\/span><\/a> (ubrogepant)<\/span><\/td>\n$1,442 for 10, 100mg tablets<\/span><\/td>\n$971 for 10, 100mg tablets of <\/span>brand-name<\/span> Ubrelvy<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Reyvow<\/span><\/a> (lasmiditan)<\/span><\/td>\n$1,001 for 8, 100mg tablets<\/span><\/td>\n$686 for 8, 100 mg tablets of <\/span>brand-name<\/span> Reyvow<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Nurtec<\/span> ODT<\/span><\/a> (<\/span>rimegepant<\/span>)<\/span><\/td>\n$1,372 for 1, 8 tablets disintegrating box<\/span><\/td>\n$870 for 1, 8-tablet disintegrating box of <\/span>brand-name<\/span> Nurtec<\/span> ODT<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Vyepti<\/span> <\/a>(<\/span>eptinezumab<\/span>)<\/span><\/td>\n$9,343 for 3, 1mL of 100mg\/mL vials<\/span><\/td>\n$5,542 for 3, 1mL of 100mg\/mL of <\/span>brand-name<\/span> Vyepti<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Inderal LA <\/span><\/a>(<\/span>propranolol<\/span><\/a>)<\/span><\/td>\n$2,290 for 30, 60 mg capsules<\/span><\/td>\n$15 for 30, 60 mg capsules of generic Inderal LA<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Toprol XL<\/span><\/a> (<\/span>metoprolol<\/span><\/a>)<\/span><\/td>\n$160 for 90, 25mg tablets<\/span><\/td>\n$9 for 90, 25mg tablets of generic Toprol XL<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Imitrex<\/span><\/a> (<\/span>sumtatriptan<\/span><\/a>)<\/span><\/td>\n$844 for 9, 100mg tablets<\/span><\/td>\n$6 for 9, 100mg tablets of generic Imitrex<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Zomig<\/span><\/a> (<\/span>zolmitriptan<\/span><\/a>)<\/span><\/td>\n$1,332 for 9, 5mg tablets<\/span><\/td>\n$25 for 9, 5mg tablets of generic Zomig<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Maxalt<\/span><\/a> (<\/span>rizatriptan<\/span><\/a>)<\/span><\/td>\n$491 for 9, 10mg tablets<\/span><\/td>\n$8 for 9, 10 mg tablets of generic Maxalt<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Relpax<\/span><\/a> (<\/span>eletriptan<\/span><\/a>)<\/span><\/td>\n$577 for 6, 40mg tablets<\/span><\/td>\n$27 for 6, 40mg tablets of generic Relpax<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Advil<\/span><\/a> (<\/span>ibuprofen<\/span><\/a>)<\/span><\/td>\n$5 for 100, 200mg tablets<\/span><\/td>\n$1 for 100, 200mg tablets of generic Advil<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug<\/span><\/i> prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of <\/span><\/i>brand-name<\/span><\/i> drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the \u201cSavings options\u201d link to see the latest drug prices.<\/span><\/i><\/p>\n

Top 5 <\/span>Ajovy<\/span> alternatives<\/span><\/h2>\n

The following are some of the most common alternatives to <\/span>Ajovy<\/span>.<\/span><\/p>\n

2. <\/span>Emgality<\/span><\/h3>\n

Emgality<\/span><\/a> is also a <\/span>brand-name<\/span> injectable medication used as a preventive migraine treatment. However, it is also prescribed to treat episodic <\/span>cluster headaches<\/span>. <\/span>Emgality<\/span> belongs to the <\/span>CGRP antagonist<\/span> drug class. For the <\/span>prevention of migraines<\/span>, it is injected under the skin once a month, but <\/span>healthcare providers<\/span> usually prescribe an initial loading dose\u2014a dose that\u2019s higher than the usual maintenance dose\u2014to help the drug start working quickly. Like <\/span>Ajovy<\/span>, <\/span>Emgality<\/span> is only available as a <\/span>brand-name<\/span> medication, and there are no generic versions available.\u00a0<\/span><\/p>\n

3. <\/span>Vyepti<\/span><\/h3>\n

Vyepti<\/span><\/a> is another commonly used <\/span>CGRP antagonist<\/span> for <\/span>migraine prevention<\/span> in adults. While it is a <\/span>brand-name<\/span> injectable drug like <\/span>Ajovy<\/span>, <\/span>Vyepti<\/span> is administered through intravenous infusion only, whereas <\/span>Ajovy<\/span> can be self-administered <\/span>subcutaneously<\/span> (under the skin). This means <\/span>Vyepti<\/span> will be given by a <\/span>healthcare provider<\/span> in a healthcare setting. It is also given once every three months. The <\/span>most common side effects<\/span> of <\/span>Vyepti<\/span> include a stuffy nose, scratchy throat, and <\/span>allergic reactions<\/span>.\u00a0<\/span><\/p>\n

4. <\/span>Nurtec<\/span> ODT<\/span><\/h3>\n

Another popular <\/span>CGRP antagonist<\/span> is <\/span>Nurtec<\/span> ODT<\/span><\/a>. Unlike <\/span>Ajovy<\/span>, <\/span>Nurtec<\/span> ODT is taken orally and comes as an orally disintegrating tablet that should be placed on or under the tongue for disintegration. <\/span>Nurtec<\/span> ODT can be used for both <\/span>episodic migraine prevention<\/span> and sudden <\/span>migraine attacks<\/span>. For <\/span>migraine prevention<\/span>, the recommended dosage is 75 mg once every other day. <\/span>Nurtec<\/span> ODT commonly causes nausea, abdominal pain, and indigestion.\u00a0<\/span><\/p>\n

5. Inderal LA (<\/span>propranolol<\/span>)<\/span><\/h3>\n

Inderal LA<\/span><\/a> is a beta blocker that is <\/span>FDA-approved<\/span> to treat a variety of conditions, including <\/span>hypertension<\/span> (<\/span>high blood pressure<\/span>), angina (chest pain), hypertrophic subaortic stenosis (a condition where the heart muscle is abnormally thick), and <\/span>migraine prevention<\/span>. <\/span>It is thought to work for <\/span>migraine prevention<\/span> by blocking certain receptors in <\/span>blood vessels<\/span> in the brain<\/span>. Inderal LA is available as extended-release capsules, and the recommended dosage is 80-240 mg orally once daily.\u00a0<\/span><\/p>\n

Over-the-counter <\/span>migraine medication<\/span><\/h2>\n

Another <\/span>treatment option<\/span> for migraines is over-the-counter (OTC) medications. <\/span>For some, OTC options are often more accessible and affordable than prescription treatments. In fact, research shows that by the time a patient sees a headache specialist, they have tried an average of <\/span>more than two<\/span><\/a> OTC medications for their migraine. However, they still have their potential risks, so it\u2019s best to consult a <\/span>healthcare provider<\/span> before starting any new OTC <\/span>migraine medications<\/span>.\u00a0<\/span><\/p>\n

Common OTC migraine treatments include:\u00a0<\/span><\/p>\n

1. <\/span>Aimovig<\/span><\/h3>\n

Aimovig<\/span><\/a> (<\/span>erenumab<\/span>) is another <\/span>brand-name<\/span> injectable medication used to prevent migraines. Like <\/span>Ajovy<\/span><\/a>, <\/span>Aimovig<\/span> belongs to the drug class known as <\/span>CGRP antagonists<\/span>, and both medications are <\/span>monoclonal antibodies<\/span>. However, <\/span>Aimovig<\/span> is injected under the skin once a month, while <\/span>Ajovy<\/span> is injected either once a month or once every three months. Both medications can cause <\/span>injection site reactions<\/span>, such as pain, redness, or itching, but some people also experience <\/span>constipation<\/span> and muscle spasms with <\/span>Aimovig<\/span>.\u00a0<\/span><\/p>\n