{"id":633408,"date":"2025-09-03T15:48:00","date_gmt":"2025-09-03T19:48:00","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633408"},"modified":"2026-04-15T15:02:09","modified_gmt":"2026-04-15T19:02:09","slug":"advair-generic","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/advair-generic\/","title":{"rendered":"Advair generic: Options for asthma and COPD"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Advair is a brand-name prescription combination medication approved by the Food and Drug Administration (FDA). It contains an inhaled corticosteroid (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/inhaled-corticosteroids\"><span style=\"font-weight: 400;\">ICS<\/span><\/a><span style=\"font-weight: 400;\">) and long-acting beta agonist (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/long-acting-beta-agonists\"><span style=\"font-weight: 400;\">LABA<\/span><\/a><span style=\"font-weight: 400;\">) bronchodilator to help reduce inflammation and open airways. Advair is available in two different dosage forms: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-hfa\"><span style=\"font-weight: 400;\">Advair HFA<\/span><\/a><span style=\"font-weight: 400;\">, approved for asthma, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-diskus\"><span style=\"font-weight: 400;\">Advair Diskus<\/span><\/a><span style=\"font-weight: 400;\">, approved for asthma and COPD. For those looking to save on costs, generics are available for both. Advair Diskus has been available as a generic since 2019 with Wixela Inhub, and a generic version of Advair HFA became available by March 2023.<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th class=\"title\" role=\"columnheader\" colspan=\"2\" scope=\"col\">\n<h2 id=\"advair-generic-availability\"><span style=\"font-weight: 400;\">Advair generic availability<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Generic name<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Fluticasone-Salmeterol<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>FDA approval date of the generic version<\/b><\/td>\n<td><span style=\"font-weight: 400;\">January 2019<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Is there a generic available for sale in the U.S.?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"what-are-the-differences-between-generic-vs-brand-name-advair\"><span style=\"font-weight: 400;\">What are the differences between generic vs. brand-name Advair?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Advair HFA and Advair Diskus contain the same active ingredients, but their medication delivery systems, FDA-approved indications, dosages, and age restrictions differ.<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-hfa\/what-is\"><span style=\"font-weight: 400;\">Advair HFA<\/span><\/a><span style=\"font-weight: 400;\"> comes in a traditional canister-shaped inhaler and is <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2021\/021254s036lbl.pdf\"><span style=\"font-weight: 400;\">approved<\/span><\/a><span style=\"font-weight: 400;\"> for the treatment of asthma only. In contrast, Advair Diskus is an inhalation powder that comes in a disc-shaped inhaler and is <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2019\/021077s061lbl.pdf\"><span style=\"font-weight: 400;\">approved<\/span><\/a><span style=\"font-weight: 400;\"> for the treatment of asthma and COPD.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here are some other key differences between Advair HFA and Diskus:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Advair HFA is approved for adults and adolescents 12 and older, whereas Advair Diskus is approved for adults, adolescents, and children aged 4 to 11.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Advair HFA is available in strengths providing 45 to 230 mcg of fluticasone with 21 mcg of salmeterol per puff. Advair Diskus comes in strengths of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-diskus\/dosage\"><span style=\"font-weight: 400;\">100 to 500 mcg of fluticasone with 50 mcg of salmeterol per puff<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Advair HFA is taken as two inhalations twice daily, or a total of four puffs per day. Advair Diskus is dosed as one inhalation twice daily, for a total of two puffs per day.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Advair Diskus contains milk protein, which can make it unsafe for individuals with a severe milk protein allergy.<\/span><\/li>\n<\/ul>\n<h2 id=\"is-a-generic-advair-available\"><span style=\"font-weight: 400;\">Is a generic Advair available?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Yes, Advair is available in generic form, with the active ingredients fluticasone and salmeterol. There is also a branded generic for Advair Diskus.\u00a0<\/span><\/p>\n<h3 id=\"advair-diskus-generic-inhaler\"><span style=\"font-weight: 400;\">Advair Diskus generic inhaler<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Advair Diskus is available as generic fluticasone-salmeterol in a diskus form. There&#8217;s also a branded generic version of Advair Diskus, sold under the brand name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wixela-inhub\/what-is\"><span style=\"font-weight: 400;\">Wixela Inhub<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/investor.mylan.com\/news-releases\/news-release-details\/mylan-announces-fda-approval-wixelatm-inhubtm-fluticasone\"><span style=\"font-weight: 400;\">approved by the FDA<\/span><\/a><span style=\"font-weight: 400;\"> in January 2019 and manufactured by Mylan. Since then, other manufacturers have produced generic versions of Advair Diskus.\u00a0<\/span><\/p>\n<h3 id=\"advair-hfa-generic-inhaler\"><span style=\"font-weight: 400;\">Advair HFA generic inhaler<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The active ingredients in the generic form of Advair HFA are the same as those in its brand-name counterpart. An <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/authorized-generics\/\"><span style=\"font-weight: 400;\">authorized generic<\/span><\/a><span style=\"font-weight: 400;\"> fluticasone-salmeterol HFA aerosol inhaler <\/span><a href=\"https:\/\/nctr-crs.fda.gov\/fdalabel\/services\/spl\/set-ids\/666c5b12-a4f7-4c53-8261-4742b5e5a6df\/spl-doc\"><span style=\"font-weight: 400;\">became available<\/span><\/a><span style=\"font-weight: 400;\"> in March 2023.\u00a0<\/span><\/p>\n<h2 id=\"how-much-does-generic-advair-cost\"><span style=\"font-weight: 400;\">How much does generic Advair cost?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Advair HFA and Advair Diskus have similar average retail prices. Prices vary by pharmacy and location, but the average cost of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-hfa\"><span style=\"font-weight: 400;\">Advair HFA<\/span><\/a><span style=\"font-weight: 400;\"> without insurance is about $510 for one 115\u201321 mcg\/actuation inhaler, which delivers 120 actuations (act) or inhalations. In comparison, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-diskus\"><span style=\"font-weight: 400;\">Advair Diskus<\/span><\/a><span style=\"font-weight: 400;\"> costs about $502 without insurance for one 250\u201350 mcg\/act inhaler, which delivers 60 inhalations. Both inhalers provide enough doses for one month with typical use.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wixela-inhub\"><span style=\"font-weight: 400;\">SingleCare Advair Diskus coupon<\/span><\/a><span style=\"font-weight: 400;\"> may help reduce the cost to around $58 for one 250\u201350 mcg\/act inhaler of Wixela Inhub or fluticasone-salmeterol in diskus form. As for generic Advair HFA, you could pay $289 instead of $510 per 1, 12 gm of 115\u201321 mcg\/act inhaler with a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advair-hfa\"><span style=\"font-weight: 400;\">SingleCare Advair HFA coupon<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th class=\"title\" role=\"columnheader\" colspan=\"4\" scope=\"col\">\n<h3 id=\"brand-vs-generic-advair-prices\"><span style=\"font-weight: 400;\">Brand vs. generic Advair prices<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Cost details<\/b><\/td>\n<td><b>Brand-name Adviar HFA<\/b><\/td>\n<td><b>Brand-name Advair Diskus<\/b><\/td>\n<td><b>Fluticasone salmeterol generic<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Average cost without insurance<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$511 for 1, 12gm of 115-21mcg\/act (120 inhalations) inhaler of Advair HFA<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$<\/span><span style=\"font-weight: 400;\">510 for 1, 115<\/span><span style=\"font-weight: 400;\">\u2013<\/span><span style=\"font-weight: 400;\">21 mcg\/act inhaler of Advair Diskus<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$503 per 1, 250<\/span><span style=\"font-weight: 400;\">\u2013<\/span><span style=\"font-weight: 400;\">50 mcg\/act inhaler of generic Advair Diskus at CVS Pharmacy<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">SingleCare&#8217;s lowest price<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$314 for 1, 12gm of 115-21mcg\/act (120 inhalations) inhaler of Advair HFA<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$502 for 1, 250<\/span><span style=\"font-weight: 400;\">\u2013<\/span><span style=\"font-weight: 400;\">50 mcg\/act inhaler of Advair Diskus<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$58 per 1, 250<\/span><span style=\"font-weight: 400;\">\u2013<\/span><span style=\"font-weight: 400;\">50 mcg\/act inhaler of generic Advair Diskus at CVS Pharmacy<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Free coupons<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/advair-hfa\"><span style=\"font-weight: 400;\">Advair HFA coupons<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/advair-diskus\"><span style=\"font-weight: 400;\">Advair Diskus coupons<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/fluticasone-salmeterol\"><span style=\"font-weight: 400;\">Fluticasone salmeterol coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><small><i><span style=\"font-weight: 400;\">Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of April 15, 2026. The listed price, without insurance, refers to the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.\u00a0<\/span><\/i><\/small><\/p>\n<h2 id=\"is-advair-covered-by-insurance\"><span style=\"font-weight: 400;\">Is Advair covered by insurance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Advair may be covered by commercial insurance and Medicare plans. However, insurance coverage will vary by plan. Although many insurance plans may cover Advair HFA and Advair Diskus, they may be found on higher tiers of preferred drug lists or formularies. In other words, they may come with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/advair-savings-guide\/\"><span style=\"font-weight: 400;\">higher out-of-pocket costs<\/span><\/a><span style=\"font-weight: 400;\"> as brand-name drugs.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Insurance plans may prefer to cover the generic versions, meaning you&#8217;ll often pay a lower copay for the generic medication versus the brand-name one. While Medicare Part D generally covers fluticasone-salmeterol, out-of-pocket costs can vary. Medicaid coverage will depend on the state.<\/span><\/p>\n<h2 id=\"how-do-you-get-advair-covered-by-insurance\"><span style=\"font-weight: 400;\">How do you get Advair covered by insurance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If Advair is <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/advair-hfa-without-insurance\/\"><span style=\"font-weight: 400;\">not covered by insurance<\/span><\/a><span style=\"font-weight: 400;\">, your doctor or healthcare provider may need to submit a prior authorization request. This process involves sending the insurance company documentation that explains why Advair is medically necessary.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If insurance denies coverage, you and your healthcare provider can file an appeal. In some cases, you may have to try an alternative that&#8217;s covered. Opting for the generic version could increase the chances of coverage.\u00a0<\/span><\/p>\n<h2 id=\"generic-alternatives-to-advair\"><span style=\"font-weight: 400;\">Generic alternatives to Advair<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">A generic version of Advair is available, but some people may prefer an alternative due to cost, side effects, or other factors. Alternatives to Advair include other inhalers that may contain different ingredients or combinations of ingredients.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/advair-diskus-alternatives\/\"><span style=\"font-weight: 400;\">Alternatives to Advair Diskus<\/span><\/a><span style=\"font-weight: 400;\"> that may come in generic forms include:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">ICS\/LABA combination inhalers:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/wixela-inhub\"><span style=\"font-weight: 400;\">Wixela Inhub<\/span><\/a><span style=\"font-weight: 400;\"> (fluticasone-salmeterol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/breyna\"><span style=\"font-weight: 400;\">Breyna<\/span><\/a><span style=\"font-weight: 400;\"> (budesonide-formoterol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">AirDuo RespiClick (fluticasone-salmeterol)<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">ICS inhalers:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/pulmicort\"><span style=\"font-weight: 400;\">Pulmicort<\/span><\/a><span style=\"font-weight: 400;\"> (budesonide)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flovent (<\/span><a href=\"http:\/\/www.singlecare.com\/prescription\/fluticasone-propionate-diskus\"><span style=\"font-weight: 400;\">fluticasone<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These inhalers are potential options available as generics. They&#8217;re generally used as maintenance medications that need to be used daily to control symptoms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It&#8217;s important to consult a healthcare provider for alternatives, since the best option will depend on the reason for switching. For example, if your asthma symptoms are well-controlled, you may be able to switch to an ICS-only inhaler, such as fluticasone.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In any case, a rescue inhaler like Ventolin HFA (albuterol) is often needed on hand for sudden breathing problems or an asthma attack.<\/span><\/p>\n<h2 id=\"how-to-switch-from-advair-to-a-generic-version\"><span style=\"font-weight: 400;\">How to switch from Advair to a generic version<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Healthcare professionals often prescribe generic Advair right off the bat. But if you&#8217;re currently using a brand-name Advair inhaler, the first step to switching is talking to your healthcare provider.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">&#8220;When my patients have an opportunity to use a generic form of a costly medication, I am enthusiastically supportive of that change in most cases,&#8221; says <\/span><a href=\"https:\/\/www.joypointsolutions.com\/about-1\"><span style=\"font-weight: 400;\">Chrissie Ott, MD<\/span><\/a><span style=\"font-weight: 400;\">, a double board-certified internist and pediatrician in Portland, Oregon. &#8220;Generic forms of medication are required to meet the same standards as the prescription medication, so in most cases, there is very little difference.&#8221; That said, Dr. Ott recommends monitoring symptoms closely after switching to the generic Advair, just in case you notice a difference in how your body responds.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are two cases in which your provider might prescribe brand-name Advair over its generic equivalent. The first is when a patient simply prefers the brand-name drug, according to <\/span><a href=\"https:\/\/www.memorialcare.org\/providers\/jimmy-johannes\"><span style=\"font-weight: 400;\">Jimmy Johannes, MD<\/span><\/a><span style=\"font-weight: 400;\">, pulmonologist and critical care medicine specialist at MemorialCare Long Beach Medical Center in Long Beach, California. &#8220;Often this is because they perceive superior response or fewer side effects with the brand-name product,&#8221; Dr. Johannes explains. The second case, according to Dr. Ott, is when a patient has an allergic reaction to one of the generic drug&#8217;s inactive ingredients, such as a binder or dye.<\/span><\/p>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ultimately, it&#8217;s important to consult a healthcare professional if you are interested in switching from brand-name Advair to a generic equivalent. Though generic drugs are considered just <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/are-generic-drugs-as-good-as-brand-name-medicines\/\"><span style=\"font-weight: 400;\">as safe and effective as brand-name drugs<\/span><\/a><span style=\"font-weight: 400;\">, there may be small differences in inactive ingredients or in the delivery system. Direct any questions about Advair versus generic Advair to your healthcare provider or a pharmacist familiar with your medical history and other medications.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Advair is a brand-name prescription combination medication approved by the Food and Drug Administration (FDA). It contains an inhaled corticosteroid (ICS) and long-acting beta agonist (LABA) bronchodilator to help reduce inflammation and open airways. Advair is available in two different dosage forms: Advair HFA, approved for asthma, and Advair Diskus, approved for asthma and COPD. [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":633409,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10965,20946,3418],"coauthors":[20942],"class_list":["post-633408","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-asthma","tag-copd","tag-generic-drugs","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Advair generic: Options for asthma and COPD<\/title>\n<meta name=\"description\" content=\"Generic versions of Advair Diskus and Advair HFA are available and contain the same active ingredients: fluticasone propionate and salmeterol.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, 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