{"id":633598,"date":"2025-09-18T13:02:25","date_gmt":"2025-09-18T17:02:25","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633598"},"modified":"2026-01-28T14:06:23","modified_gmt":"2026-01-28T19:06:23","slug":"cefdinir-interactions","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/cefdinir-interactions\/","title":{"rendered":"Cefdinir interactions to avoid"},"content":{"rendered":"

Cefdinir<\/span><\/a> is a <\/span>cephalosporin antibiotic<\/span><\/a>\u2014specifically a <\/span>third-generation cephalosporin<\/span><\/a>\u2014used to treat certain types of bacterial infections in adults and children. <\/span>Cefdinir<\/span><\/a> is often referred to by the brand name Omnicef, although now it is only available in its generic form. Some of the bacterial infections cefdinir treats include <\/span>bronchitis<\/span><\/a>, <\/span>pneumonia<\/span><\/a>, <\/span>ear infections<\/span><\/a>, <\/span>sinus infections<\/span><\/a>, <\/span>strep throat<\/span><\/a>, skin infections, and <\/span>tonsillitis<\/span><\/a>. Cefdinir can interact with certain medicines, such as antacids, iron supplements, and the <\/span>gout<\/span><\/a> medication probenecid. If you are taking cefdinir, it is important to know about its interactions so you can have the most effective and safe treatment.<\/span><\/p>\n

Cefdinir drug and vitamin interactions<\/span><\/h2>\n

Cefdinir can interact with certain medications and supplements, including antacids, iron supplements, and probenecid.<\/span><\/p>\n\n\n\n\n\n\n
Drug class or group name<\/b><\/td>\nDrug name<\/b><\/td>\nInteractions\/side effects<\/b><\/td>\n<\/tr>\n
Antacids that contain aluminum or magnesium<\/td>\nGaviscon, Maalox, Mylanta, Rolaids, and generic versions<\/td>\nInterferes with the absorption of cefdinir, which could make the antibiotic not work as well<\/td>\n<\/tr>\n
Iron supplements<\/td>\nFeoSol, Slow Fe, ferrous sulfate and other generic versions, multivitamins with iron<\/td>\nInterferes with the absorption of cefdinir, which could make the antibiotic not work as well; can also cause red stools<\/td>\n<\/tr>\n
Anti-gout medication<\/td>\nProbenecid<\/td>\nProbenecid slows down how quickly cefdinir leaves the body, which leads to higher levels of cefdinir and more side effects<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Antacids<\/span><\/h2>\n

People often take over-the-counter (OTC) antacids to relieve symptoms of <\/span>heartburn<\/span><\/a> or indigestion. Antacids work by reducing the amount of acid in your stomach. Different antacids contain different ingredients, but many contain magnesium and\/or aluminum. These types of antacids interact with cefdinir, reducing the absorption of the antibiotic and also making it take longer to work. If you take an antacid at around the same time as cefdinir, it could cause the antibiotic to be less effective. To avoid this interaction, take cefdinir at least two hours before or after an antacid with magnesium or aluminum. Or, you can take an antacid that does not contain magnesium or aluminum, such as Tums, which contains calcium carbonate. You can always ask your pharmacist if you are not sure what ingredients are in your antacid. Some examples of antacids that contain magnesium or aluminum include:<\/span><\/p>\n