{"id":633651,"date":"2025-10-06T09:30:23","date_gmt":"2025-10-06T13:30:23","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633651"},"modified":"2025-09-24T16:44:19","modified_gmt":"2025-09-24T20:44:19","slug":"foods-to-avoid-while-taking-entresto","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/foods-to-avoid-while-taking-entresto\/","title":{"rendered":"6 foods to avoid on Entresto"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/entresto#coupon-prices\"><span style=\"font-weight: 400;\">Entresto<\/span><\/a><span style=\"font-weight: 400;\"> is a brand-name prescription drug approved by the Food and Drug Administration (FDA) to treat heart failure. It combines sacubitril, a neprilysin inhibitor, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/valsartan\"><span style=\"font-weight: 400;\">valsartan<\/span><\/a><span style=\"font-weight: 400;\">, an angiotensin II receptor blocker (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/angiotensin-ii-receptor-blockers\"><span style=\"font-weight: 400;\">ARB<\/span><\/a><span style=\"font-weight: 400;\">). Entresto is categorized in a new drug class called angiotensin receptor-neprilysin inhibitors (ARNIs).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People taking Entresto should consult their healthcare providers to determine if any dietary changes are necessary to support the medication\u2019s effectiveness and enhance heart health. In many cases, patients taking Entresto are advised to avoid processed foods and those<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/high-potassium-foods-to-avoid\/\"><span style=\"font-weight: 400;\">high in potassium<\/span><\/a><span style=\"font-weight: 400;\">, salt, or fat.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Entresto with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tEntresto 24-26 mg (60 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-cvs.svg\" alt=\"CVS Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$34.83<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/entresto#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/entresto#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-publix.svg\" alt=\"Publix\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$52.71<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/entresto#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/entresto#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/entresto#blog-cta\" class=\"coupon-see-all-btn\">See Entresto prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"how-entresto-works\"><span style=\"font-weight: 400;\">How Entresto works<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/entresto\/what-is\"><span style=\"font-weight: 400;\">Entresto (sacubitril\/valsartan)<\/span><\/a><span style=\"font-weight: 400;\"> reduces the risk of heart-related death and hospitalization in people with heart failure. How? Relaxing <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507904\/\"><span style=\"font-weight: 400;\">and widening blood vessels<\/span><\/a><span style=\"font-weight: 400;\">, which increases blood flow and lowers blood pressure. The drug\u2019s active ingredients also have a secondary effect of decreasing sodium and fluid levels in the body, which can help prevent <\/span><a href=\"https:\/\/www.heart.org\/en\/health-topics\/heart-failure\/warning-signs-of-heart-failure\"><span style=\"font-weight: 400;\">symptoms of heart failure<\/span><\/a><span style=\"font-weight: 400;\">, such as swelling and shortness of breath.\u00a0<\/span><\/p>\n<h2 id=\"6-foods-to-avoid-with-entresto\"><span style=\"font-weight: 400;\">6 foods to avoid with Entresto<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">People take Entresto because they have a heart condition. Although no foods directly interact with Entresto, it\u2019s essential to follow healthcare professionals\u2019 recommendations for dietary changes that support heart health and minimize the risk of Entresto side effects, such as hyperkalemia (high blood potassium) and dizziness.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here are some foods your prescriber might recommend avoiding or limiting while taking Entresto:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Potassium-rich foods<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Salty foods<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Salt substitutes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatty foods<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Processed foods<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Alcohol<\/span><\/li>\n<\/ol>\n<h3 id=\"1-high-potassium-foods\"><span style=\"font-weight: 400;\">1. High potassium foods<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hyperkalemia (high blood potassium levels) is a serious side effect that develops in<\/span> <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=000dc81d-ab91-450c-8eae-8eb74e72296f\"><span style=\"font-weight: 400;\">approximately 12% of Entresto users<\/span><\/a><span style=\"font-weight: 400;\">. Entresto can reduce the body\u2019s ability to eliminate potassium, creating a buildup in the bloodstream. Given that, limiting potassium-rich foods and potassium supplements can reduce the risk of side effects on Entresto.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/www.dietaryguidelines.gov\/food-sources-potassium\"><span style=\"font-weight: 400;\">Dietary Guidelines for America<\/span><\/a><span style=\"font-weight: 400;\"> outlines the amount of potassium in many common foods. Foods with the most potassium include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dark green vegetables such as beet greens, Swiss chard, and spinach<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Legumes such as lima beans and adzuki beans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin-on baked potatoes and yams<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fruits such as jackfruit, kiwi, cantaloupe, and banana<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fruit juices such as prune juice, passionfruit juice, and pomegranate juice<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">It\u2019s important to know that many people do not experience symptoms until high potassium levels get dangerously high, even life-threatening. Signs of high levels of potassium include an irregular heart rhythm, muscle weakness, trouble breathing, and, in some cases, cardiac arrest (heart attack).\u00a0<\/span><\/p>\n<h3 id=\"2-high-sodium-foods\"><span style=\"font-weight: 400;\">2. High sodium foods<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Consuming too much sodium can undermine the benefits of Entresto. The drug works to lower blood pressure, but <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/salt-good-or-bad-for-you\/\"><span style=\"font-weight: 400;\">sodium intake<\/span><\/a><span style=\"font-weight: 400;\"> has been<\/span> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6770596\/\"><span style=\"font-weight: 400;\">linked to high blood pressure<\/span><\/a><span style=\"font-weight: 400;\">. Additionally, excessive sodium intake can exacerbate swelling, a side effect of Entresto, according to<\/span> <a href=\"https:\/\/www.linkedin.com\/in\/dominguez-danielle\/\"><span style=\"font-weight: 400;\">Dani Dominguez<\/span><\/a><span style=\"font-weight: 400;\">, RDN, a registered dietitian nutritionist and founder of<\/span> <a href=\"http:\/\/www.sunbrightwellness.com\/\"><span style=\"font-weight: 400;\">SunBright Wellness<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">High-sodium foods to avoid include the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Processed and cured meats such as bacon, ham, cold cuts, and hot dogs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Canned soups<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Potato chips<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pickles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pasta sauces<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast food<\/span><\/li>\n<\/ul>\n<h3 id=\"3-salt-substitutes\"><span style=\"font-weight: 400;\">3. Salt substitutes<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Unfortunately, salt lovers can\u2019t simply swap their table salt for salt substitutes while on Entresto. Many salt substitutes <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1124926\/\"><span style=\"font-weight: 400;\">contain potassium chloride<\/span><\/a><span style=\"font-weight: 400;\">, so consuming them can lead to hyperkalemia while taking Entresto.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.jrnjournal.org\/article\/S1051-2276(11)00250-0\/fulltext\"><span style=\"font-weight: 400;\">Salt substitutes that contain potassium<\/span><\/a><span style=\"font-weight: 400;\"> include (but are not limited to):<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">No Salt<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nu-Salt<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Morton\u2019s Salt Substitute\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Entresto users should check the nutrition label on any salt substitutes before using them to season their food.<\/span><\/p>\n<h3 id=\"4-fatty-foods\"><span style=\"font-weight: 400;\">4. Fatty foods<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Healthcare providers typically tell patients with heart disease to<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34649831\/\"><span style=\"font-weight: 400;\">limit their saturated fat intake<\/span><\/a><span style=\"font-weight: 400;\">. \u201cSaturated fats are found mainly in animal products such as fatty cuts of meat, cheese, and butter, and are common in fried foods,\u201d Dominguez says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you have heart failure, your heart is already working extra hard, says <\/span><a href=\"https:\/\/www.theagingparentcoach.com\/\"><span style=\"font-weight: 400;\">Barbara Sparacino, MD<\/span><\/a><span style=\"font-weight: 400;\">, a triple board-certified healthcare provider. \u201cSwapping in olive oil, nuts, or fish keeps the pipes [aka arteries] clean and the job easier. Cleaner pipes equal a lighter load on your heart,\u201d Dr. Sparacino explains.\u00a0<\/span><\/p>\n<h3 id=\"5-processed-foods\"><span style=\"font-weight: 400;\">5. Processed foods<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Processed foods are not a food group. Instead, it\u2019s an umbrella term for prepackaged foods and snacks, which tend to be high in sodium, sugar, saturated fat, or all three. High sodium intake, in particular, can raise blood pressure and cause fluid retention, two issues that Entresto is prescribed to help manage in people with heart failure. Processed foods may also contain additives that make it harder to maintain a balanced diet, which is essential for supporting overall heart health. Choosing fresh, whole foods instead helps Entresto work more effectively while lowering the risk of worsening heart symptoms.<\/span><\/p>\n<h3 id=\"6-alcohol\"><span style=\"font-weight: 400;\">6. Alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">It\u2019s common to wonder if drinking alcohol is okay on Entresto since many drugs shouldn\u2019t <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/alcohol-and-medication\/https:\/\/www.singlecare.com\/blog\/alcohol-and-medication\/\"><span style=\"font-weight: 400;\">be mixed with alcohol<\/span><\/a><span style=\"font-weight: 400;\">. Dr. Sparacino says a glass of wine \u201cnow and then\u201d while taking Entresto is usually fine, but regular or heavy drinking is bad news. \u201cAlcohol stresses the heart and can mess with your meds,\u201d she adds. This is especially true of older adults on Entresto, as the effects of alcohol can hit faster and last longer in adults ages 65 and older, according to the<\/span> <a href=\"https:\/\/www.niaaa.nih.gov\/alcohols-effects-health\/aging-and-alcohol\"><span style=\"font-weight: 400;\">National Institute on Alcohol Abuse and Alcoholism<\/span><\/a> <span style=\"font-weight: 400;\">(NIAAA). \u201cThis ups the risk of falls, confusion, medication problems, even depression or accidents,\u201d Dr. Sparacino says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Possible <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/entresto\/what-is\"><span style=\"font-weight: 400;\">drug interactions<\/span><\/a><span style=\"font-weight: 400;\"> to be aware of include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aliskiren (in individuals with diabetes)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">ACE inhibitors should not be taken within 36 hours of taking Entresto.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lithium toxicity may occur if lithium is taken with Entresto.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, can cause <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4636283\/\"><span style=\"font-weight: 400;\">kidney problems<\/span><\/a><span style=\"font-weight: 400;\">, including reduced kidney function and possible kidney failure, when combined with Entresto.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Taking Entresto with potassium-sparing diuretics, such as triamterene and spironolactone, may lead to high levels of potassium in the blood.\u00a0<\/span><\/li>\n<\/ul>\n<h2 id=\"what-should-you-eat-while-taking-entresto\"><span style=\"font-weight: 400;\">What should you eat while taking Entresto?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There is no specific dietary recommendation for people taking ARNIs. That said, Dominguez recommends the DASH diet (Dietary Approaches to Stop Hypertension) to anyone with heart failure. \u201cThe idea behind this diet is to<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/heart-healthy-diet\/\"><span style=\"font-weight: 400;\">promote heart health<\/span><\/a><span style=\"font-weight: 400;\"> and lower high blood pressure, which can lower risk factors of heart failure,\u201d she says. \u201cThe DASH diet focuses on eating fruits, vegetables, whole grains, low-fat and fat-free dairy products, lean protein, beans, nuts, and seeds.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Since Entresto can reduce the fluid in your body, it\u2019s also important to stay hydrated. That means watching your intake of beverages like coffee, because caffeine has<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19774754\/\"><span style=\"font-weight: 400;\">a mild diuretic effect<\/span><\/a><span style=\"font-weight: 400;\">. Additionally, you should drink water or unsweetened liquid throughout the day, and snack on nourishing, water-rich foods like watermelon and cucumber. If you have any questions about what to eat or drink while taking Entresto, seek personalized medical advice from a healthcare professional familiar with a complete list of your other prescription and over-the-counter (OTC) medications and medical conditions.<\/span><\/p>\n<h2 id=\"gastrointestinal-side-effects-of-entresto\"><span style=\"font-weight: 400;\">Gastrointestinal side effects of Entresto<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The only common gastrointestinal <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/entresto-side-effects\"><span style=\"font-weight: 400;\">Entresto side effect<\/span><\/a><span style=\"font-weight: 400;\"> is diarrhea. The good news is that limiting alcohol and eating a heart-healthy diet of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/what-to-eat-when-stomach-is-upset-from-stress\/\"><span style=\"font-weight: 400;\">whole grains<\/span><\/a><span style=\"font-weight: 400;\"> and lean protein can help with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-to-improve-gut-health\/\"><span style=\"font-weight: 400;\">gut health<\/span><\/a><span style=\"font-weight: 400;\">, too. In other words, following the dietary advice in this article might help prevent or minimize Entresto-related diarrhea in addition to supporting the benefits of the drug itself.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Beyond diarrhea, Entresto isn\u2019t known for causing stomach problems\u2014 but hyperkalemia might. Possible <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470284\/#:~:text=Hyperkalemia%20is%20defined%20as%20a,%2C%20muscle%20weakness%2C%20or%20paralysis.\"><span style=\"font-weight: 400;\">signs of hyperkalemia<\/span><\/a><span style=\"font-weight: 400;\"> include nausea, vomiting, and diarrhea, as well as muscle weakness and irregular heartbeat. Still, it\u2019s important to remember that not everyone experiences symptoms of hyperkalemia until potassium levels are dangerously high. If you are on Entresto and experience sudden or severe nausea, vomiting, or diarrhea, seek medical advice from a healthcare professional.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Entresto is a brand-name prescription drug approved by the Food and Drug Administration (FDA) to treat heart failure. It combines sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker (ARB). Entresto is categorized in a new drug class called angiotensin receptor-neprilysin inhibitors (ARNIs). People taking Entresto should consult their healthcare providers to determine [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":633664,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[814,737,553,8905],"coauthors":[20942],"class_list":["post-633651","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-interactions","tag-heart-health","tag-nutrition","tag-seasonal","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>6 foods to avoid while taking Entresto<\/title>\n<meta name=\"description\" content=\"It\u2019s important to avoid foods high in potassium and sodium when taking Entresto in order to minimize interactions. 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