{"id":633740,"date":"2025-10-02T14:42:13","date_gmt":"2025-10-02T18:42:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633740"},"modified":"2026-01-28T14:07:31","modified_gmt":"2026-01-28T19:07:31","slug":"jardiance-10-mg-vs-25-mg","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/jardiance-10-mg-vs-25-mg\/","title":{"rendered":"Jardiance 10 mg vs 25 mg: Which dose is right for you?"},"content":{"rendered":"

\u00a0<\/span>Jardiance<\/span><\/a> is the brand name for empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It\u2019s FDA approved to treat Type 2 diabetes in adults and children, who are at least 10 years of age, in conjunction with diet and exercise. <\/span>Jardiance<\/span><\/a> is also approved to reduce the risk of cardiovascular death in adults with Type 2 diabetes and cardiovascular disease, to reduce the risk of worsening renal function in adults with chronic kidney disease, and to reduce the risk of hospitalization and cardiovascular death in adults with heart failure or chronic kidney disease. Jardiance works by removing excess glucose (sugar) from the body through the kidneys.<\/span><\/p>\n

Jardiance is taken orally once per day at either a 10 mg or 25 mg dose. Wondering what the difference is between Jardiance 10 mg vs. 25 mg? Most people who take Jardiance take a 10 mg dose, but a 25 mg dose is sometimes used in patients with Type 2 diabetes who need more help reducing their blood sugar.<\/span><\/p>\n

What\u2019s the difference between Jardiance 10 mg versus 25 mg?<\/span><\/h2>\n

The 10 mg dose of Jardiance is the typical starting dose, says Linda Khoshaba, NMD, naturopathic endocrinologist and founder of<\/span> Natural Endocrinology Specialists (NES)<\/span><\/a>. \u201cIt\u2019s sort of a \u2018let\u2019s see how your body does with this\u2019 approach,\u201d she says. If your blood sugar levels aren\u2019t being lowered sufficiently with the 10 mg dose, your doctor may bump you up to 25 mg for a more potent effect. \u201cThe higher dose isn\u2019t automatically better for everyone\u2014it\u2019s usually reserved for when the smaller dose isn\u2019t enough,\u201d says Dr. Khoshaba.<\/span><\/p>\n

When it comes to<\/span> diabetes management<\/span><\/a>, research has shown that higher doses of Jardiance can be more effective for glycemic control. For example, a 2021 study published in the<\/span> Journal of Clinical Pharmacy and Therapeutics<\/span><\/i><\/a> found that higher doses of empagliflozin (Jardiance) result in more substantial decreases in<\/span> hemoglobin A1C<\/span><\/a>, a blood test that measures your average glucose level from the past three months. Overall, the study found that, over the course of 12 weeks, empagliflozin doses of 10, 25, and 50 mg were more effective at lowering A1C than 1, 2.5, and 5 mg. Among these doses, 25 mg performed the best overall, considering efficacy and side effects.<\/span><\/p>\n

According to DailyMed,<\/span><\/a> the 25 mg dose is typically reserved for offering extra support to patients with Type 2 diabetes. However, you can ask your provider if a higher dose is best suited for your specific medical situation.<\/span><\/p>\n

Here\u2019s what to know about conditions that Jardiance treats and 10 mg vs 25 mg dosing.<\/span>\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n
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Conditions treated by Jardiance 10 mg and 25 mg<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Condition<\/b><\/td>\n10 mg once daily<\/b><\/td>\n25 mg once daily<\/b><\/td>\n<\/tr>\n
Reduction in the risk of cardiovascular death and hospitalization in adults with heart failure<\/span><\/td>\nYes<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Reduction in the risk of kidney failure, hospitalization, and death in adults with chronic kidney disease<\/span><\/td>\nYes<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Reduction in the risk of cardiovascular death in adults with Type 2 diabetes and cardiovascular disease<\/span><\/td>\nYes<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Blood glucose control in people with Type 2 diabetes<\/span><\/td>\nYes<\/span><\/td>\nYes, if well tolerated and if further glycemic control is needed<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/span>Jardiance 10 mg vs. 25 mg: Insurance coverage and cost comparison<\/span><\/h2>\n

Most<\/span> major health insurance plans cover Jardiance<\/span><\/a>, though coverage will depend on your plan, and some providers may require<\/span> step therapy<\/span><\/a>, meaning that you must try other less expensive medications first to prove that Jardiance is a better match for your health needs. What about Medicare and Medicaid? \u201cMedicare Part D and Medicaid also usually cover Jardiance, though the exact out-of-pocket cost can depend on your plan and state,\u201d Dr. Khoshaba says.<\/span><\/p>\n

As for whether coverage varies based on a 10 mg vs. 25 mg dose of Jardiance, that shouldn\u2019t make much of a difference. \u201cIn most cases, both 10 mg and 25 mg doses are covered since they\u2019re the same medication in different strengths,\u201d Dr. Khoshaba explains. \u201cSometimes it requires <\/span>prior approval<\/span><\/a>, but typically, patients can get access to either dose.\u201d<\/span><\/p>\n

In terms of out-of-pocket costs, <\/span>copays<\/span><\/a> for Jardiance vary from one insurance company to another. Medicaid recipients typically do not have copayments for medications. People on Medicare Part D may have Jardiance copayments ranging from<\/span> $0 to $170 a month<\/span><\/a>.<\/span><\/p>\n

Jardiance without insurance<\/a> can be costly. For example, the average cost of Jardiance is about $867 for 30, 25 mg tablets. However, with a<\/span> SingleCare savings card<\/span><\/a>, you can pay around $529 for 30, 25 mg tablets.<\/span><\/p>\n\t\t

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Save up to 80% on Jardiance with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tJardiance 25 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
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\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
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\n\t\t\t\t\t$254.81\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
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\n\t\t\t\t\t$254.81\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Jardiance prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

10 mg and 25 mg Jardiance side effects<\/span><\/h2>\n

Like all medications, Jardiance can have side effects. The<\/span> most common side effects of Jardiance<\/span><\/a> are:<\/span><\/p>\n