{"id":633993,"date":"2025-10-20T14:24:04","date_gmt":"2025-10-20T18:24:04","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=633993"},"modified":"2026-03-25T11:19:41","modified_gmt":"2026-03-25T15:19:41","slug":"wegovy-pill-form","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/wegovy-pill-form\/","title":{"rendered":"Wegovy pill form: What to know about oral semaglutide"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\"> (semaglutide) is a prescription <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/glp-1-agonists\"><span style=\"font-weight: 400;\">GLP-1<\/span><\/a><span style=\"font-weight: 400;\"> medication initially approved by the Food and Drug Administration (FDA) for chronic weight management when combined with diet and exercise. Since its initial approval for weight loss, it\u2019s also been approved to reduce cardiovascular risk and treat a liver disease called MASH (metabolic dysfunction-associated steatohepatitis). For those who would rather avoid needles or cannot use injectable medications, oral alternatives might be more appealing. In this article, learn more about oral forms of semaglutide, how they compare to injectable Wegovy, and what alternatives may be available.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/how-much-does-wegovy-cost\/\"><b>How much does Wegovy cost?<\/b><\/a><\/p>\n<h2 id=\"does-wegovy-come-in-pill-form\"><span style=\"font-weight: 400;\">Does Wegovy come in pill form?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Yes, an <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/fda-approval-wegovy-pill\/\"><span style=\"font-weight: 400;\">oral form of Wegovy<\/span><\/a><span style=\"font-weight: 400;\"> was FDA approved in December, 2025. Another oral form of semaglutide, Rybelsus, has been available since 2019, but it is only FDA approved for Type 2 diabetes.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There may be <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/buy-compounded-semaglutide-online\/\"><span style=\"font-weight: 400;\">online telehealth services that offer compounded oral semaglutide<\/span><\/a><span style=\"font-weight: 400;\"> in the form of a liquid drop, tablet, or lozenge. It\u2019s important to know that <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/compounding-pharmacy\/\"><span style=\"font-weight: 400;\">compounded medications<\/span><\/a><span style=\"font-weight: 400;\"> aren\u2019t approved by the FDA, and the FDA has warned against the use of compounded GLP-1s because of the potential risks regarding <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/postmarket-drug-safety-information-patients-and-providers\/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss\"><span style=\"font-weight: 400;\">safety, effectiveness, and quality<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.myobesityteam.com\/writers\/682653ee1552ca622a3ea54b\"><span style=\"font-weight: 400;\">Jennifer Brown<\/span><\/a><span style=\"font-weight: 400;\">, MD, board-certified obesity medicine specialist at MyObesityTeam, explains why patients should be wary of compounded oral semaglutide offered online: \u201cI generally advise patients to steer clear of compounded oral semaglutide. While it may be less expensive, it\u2019s impossible to tell what components at what amounts are actually in the compounded version without an independent lab evaluation,\u201d she says. Wegovy is found to be more effective for weight loss and has less incidence of side effects when the dose is increased over time.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th class=\"title\" role=\"columnheader\" colspan=\"3\" scope=\"col\">\n<h2 id=\"compare-wegovy-pill-vs-injection\"><span style=\"font-weight: 400;\">\u00a0 \u00a0 Compare Wegovy pill vs. injection<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Differences<\/b><\/td>\n<td><b>Wegovy pill<\/b><\/td>\n<td><b>Wegovy pen<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Dosage<\/b><\/td>\n<td><span style=\"font-weight: 400;\">1.5 mg, 4 mg, 9 mg, 25 mg<\/span><\/td>\n<td><span style=\"font-weight: 400;\">0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4 mg<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Indication<\/b><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight loss and management in certain adults and adolescents ages 12 and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular risk reduction in certain adults<\/span><\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight loss and management in certain adults and adolescents ages 12 and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular risk reduction in certain adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Metabolic dysfunction-associated steatohepatitis (MASH) in certain adults<\/span><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare\u2019s lowest price<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$1,086 for 30, 1.5 mg tablets at Kroger or Harris Teeter<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$1,209 for 4, 2.4 mg pens at Publix<\/span><\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\">\n<p style=\"text-align: center;\"><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><b>Get your Wegovy coupon<\/b><\/a><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><small><i><span style=\"font-weight: 400;\">Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of March 25, 2026. <\/span><\/i><small><\/small><\/small><\/p>\n<h2 id=\"wegovy-pill-vs-injection-dosage\"><span style=\"font-weight: 400;\">Wegovy pill vs. injection dosage<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Wegovy pills are available in the following doses:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1.5 mg for days 1\u201330<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">4 mg for days 31\u201360<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">9 mg for days 61\u201390<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">25 mg for days 91 and onward<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Wegovy injections are available in the following doses:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">0.25 mg for weeks 1\u20134<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">0.5 mg for weeks 5\u20138<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1 mg for weeks 9\u201312<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">1.7 mg for weeks 13\u201316 or longer<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The maximum dose of Wegovy is 2.4 mg each week from week 17 onward. Your healthcare provider will determine the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-doses\/\"><span style=\"font-weight: 400;\">right Wegovy dose<\/span><\/a><span style=\"font-weight: 400;\"> for you. Once you achieve your desired weight, your healthcare provider may recommend decreasing or spacing out your doses.\u00a0<\/span><\/p>\n<h2 id=\"wegovy-pill-vs-injection-effectiveness\"><span style=\"font-weight: 400;\">Wegovy pill vs. injection effectiveness <\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In its <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b\"><span style=\"font-weight: 400;\">clinical trials<\/span><\/a><span style=\"font-weight: 400;\">, Wegovy tablets and pens produced similar weight loss results, although results were slightly higher among patients who use the pens. Those who used the injectable pens lost an average of 15% of their initial body weight after 68 weeks, while those who used the oral tablets lost about 14% of their body weight after 64 weeks.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The reason for the slightly higher amount of weight loss with Wegovy pens is that injectable medications are more reliably absorbed through the bloodstream. In contrast, oral tablets are absorbed through the digestive system, where factors such as food and metabolism affect how quickly they\u2019re absorbed. It may also be easier to remember to take a once-weekly injection versus a daily oral medication.\u00a0<\/span><\/p>\n<h2 id=\"are-there-any-other-oral-glp-1s-for-weight-loss\"><span style=\"font-weight: 400;\">Are there any other oral GLP-1s for weight loss?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As of this writing, there aren\u2019t any other approved oral GLP-1 weight loss drugs, but there are ongoing studies that are promising.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">An oral GLP-1 called orforglipron, being developed by drugmaker Lilly, has shown some promising results for weight loss. Compared to a placebo treatment, the daily orforglipron reduced body weight by an average of <\/span><a href=\"https:\/\/investor.lilly.com\/news-releases\/news-release-details\/lillys-oral-glp-1-orforglipron-delivers-weight-loss-average-273\"><span style=\"font-weight: 400;\">12% after 72 weeks of treatment<\/span><\/a><span style=\"font-weight: 400;\">. Clinical trials on this drug started in 2023, and more results are expected in 2025.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Another GLP-1 being studied for Type 2 diabetes is called danuglipron. Though not the main aim for these clinical studies, one trial published in 2023 showed that after 16 weeks of treatment, the <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jamanetworkopen\/fullarticle\/2805054\"><span style=\"font-weight: 400;\">average weight loss was 4\u20139 lbs<\/span><\/a><span style=\"font-weight: 400;\"> on danuglipron. In April 2025, the drug company <\/span><a href=\"https:\/\/www.pfizer.com\/news\/press-release\/press-release-detail\/pfizer-provides-update-oral-glp-1-receptor-agonist\"><span style=\"font-weight: 400;\">Pfizer discontinued development<\/span><\/a><span style=\"font-weight: 400;\"> of the medication for weight loss.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though Rybelsus is the <\/span><a href=\"https:\/\/diabetesjournals.org\/clinical\/article\/38\/1\/109\/32187\/Oral-Semaglutide\"><span style=\"font-weight: 400;\">first oral GLP-1 drug approved for Type 2 diabetes<\/span><\/a><span style=\"font-weight: 400;\"> only, it also has some research behind its use in people managing their weight. A clinical study published in 2023 found that study <\/span><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(23)01185-6\/abstract\"><span style=\"font-weight: 400;\">subjects lost on average 15% of their body weight<\/span><\/a><span style=\"font-weight: 400;\"> compared to placebo while on 50 mg, the highest dose of oral semaglutide, for 68 weeks.\u00a0\u00a0<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/resources\/weight-loss\"><b>Save on weight loss medication<\/b><\/a><\/p>\n<h2 id=\"wegovy-alternatives-without-needles\"><span style=\"font-weight: 400;\">Wegovy alternatives without needles<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are other prescription, oral <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wegovy-alternatives\/\"><span style=\"font-weight: 400;\">alternatives to Wegovy<\/span><\/a><span style=\"font-weight: 400;\">, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/contrave\"><span style=\"font-weight: 400;\">Contrave<\/span><\/a><span style=\"font-weight: 400;\"> (naltrexone and bupropion)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/qsymia\"><span style=\"font-weight: 400;\">Qsymia<\/span><\/a><span style=\"font-weight: 400;\"> (phentermine and topiramate extended release)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/phentermine-hcl\"><span style=\"font-weight: 400;\">Adipex-P<\/span><\/a><span style=\"font-weight: 400;\"> (phentermine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/xenical\"><span style=\"font-weight: 400;\">Xenical<\/span><\/a><span style=\"font-weight: 400;\"> (orlistat)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/diethylpropion-hcl\"><span style=\"font-weight: 400;\">Tenuate<\/span><\/a><span style=\"font-weight: 400;\"> (diethylpropion)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other oral medications for Type 2 diabetes can help someone manage their weight as well. \u201cFor patients who prefer pills, I lean toward Rybelsus or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/metformin\"><span style=\"font-weight: 400;\">metformin<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/jardiance\"><span style=\"font-weight: 400;\">Jardiance<\/span><\/a><span style=\"font-weight: 400;\"> (empagliflozin) is also a great option for diabetic patients,\u201d she says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lifestyle changes should not be overlooked as effective, non-injectable alternatives. Most <\/span><a href=\"https:\/\/www.ajmc.com\/view\/review-of-current-guidelines-for-the-treatment-of-obesity\"><span style=\"font-weight: 400;\">medical guidelines emphasize<\/span><\/a><span style=\"font-weight: 400;\"> that a reduced-calorie diet and increased physical activity are the foundations of obesity treatment. Dr. Aravamudhan provides examples of some lifestyle changes that can be helpful for people managing chronic high weight:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A diet high in protein with lean meats, lentils, and legumes, with lots of fruits, vegetables, whole grains, nuts, and plain yogurt<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adequate hydration with plain water, avoiding drinks with added sugars and sweeteners<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Regular daily aerobic exercises, resistance training, and stretching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Getting enough sleep, about\u00a0 seven to eight hours per night<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Learning to manage stress with proper physical and psychological tools<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Practicing mindful eating with portion control to reduce emotional eating<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other than your primary care provider or endocrinologist, it may help to manage chronic conditions like obesity with guidance from other healthcare professionals, according to Dr. Aravamudhan. Nutritionists, mental health professionals, personal trainers, or exercise therapists can help achieve desired outcomes and help minimize side effects and injuries.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Ultimately, the right choices for you will depend on many factors, including your medical history, lifestyle, and healthcare team. Always talk with your healthcare provider about which treatment approach is best for you, whether it\u2019s oral prescription medication, lifestyle changes, or a combination of them.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Wegovy (semaglutide) is a prescription GLP-1 medication initially approved by the Food and Drug Administration (FDA) for chronic weight management when combined with diet and exercise. Since its initial approval for weight loss, it\u2019s also been approved to reduce cardiovascular risk and treat a liver disease called MASH (metabolic dysfunction-associated steatohepatitis). For those who would [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":633995,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[21067,9825],"coauthors":[21072],"class_list":["post-633993","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-glp-1-drugs","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Wegovy pill form: What to know about oral semaglutide<\/title>\n<meta name=\"description\" content=\"Wegovy (semaglutide) is now available in oral tablets as well as prefilled pens. 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