{"id":635046,"date":"2026-01-16T14:37:08","date_gmt":"2026-01-16T19:37:08","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=635046"},"modified":"2026-01-16T14:37:08","modified_gmt":"2026-01-16T19:37:08","slug":"metoprolol-side-effects-elderly","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/metoprolol-side-effects-elderly\/","title":{"rendered":"Metoprolol side effects elderly patients should know about"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-tartrate\"><span style=\"font-weight: 400;\">Metoprolol<\/span><\/a><span style=\"font-weight: 400;\"> is a generic prescription drug, available as brand-name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lopressor\"><span style=\"font-weight: 400;\">Lopressor<\/span><\/a><span style=\"font-weight: 400;\">, that is prescribed for hypertension, angina pectoris (chest pain from reduced cardiac blood flow), and myocardial infarction (when blood flow to part of the heart is severely reduced, causing damage to the heart). Healthcare providers may also prescribe either<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metoprolol-tartrate-vs-metoprolol-succinate\/\"><span style=\"font-weight: 400;\"> metoprolol tartrate or metoprolol succinate<\/span><\/a><span style=\"font-weight: 400;\"> for<\/span> <a href=\"https:\/\/www.singlecare.com\/conditions\/congestive-heart-failure-treatment-and-medications\"><span style=\"font-weight: 400;\">heart failure<\/span><\/a><span style=\"font-weight: 400;\"> or<\/span> <a href=\"https:\/\/www.singlecare.com\/conditions\/migraine-treatment-and-medications\"><span style=\"font-weight: 400;\">migraine<\/span><\/a><span style=\"font-weight: 400;\"> prevention. Although metoprolol is generally considered safe, it can cause<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/metoprolol-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> like fatigue and dizziness.<\/span> <a href=\"https:\/\/www.singlecare.com\/drug-classes\/beta-blockers\"><span style=\"font-weight: 400;\">Beta blockers<\/span><\/a><span style=\"font-weight: 400;\"> like metoprolol have also been known to cause memory loss, which may be particularly concerning for older adults, and there are special precautions for older patients taking this medication.<\/span><\/p>\n<h2 id=\"common-metoprolol-side-effects-in-older-adults\"><span style=\"font-weight: 400;\">Common metoprolol side effects in older adults<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">According to clinical trial data published on the drug\u2019s label, the most common side effects of metoprolol are tiredness, dizziness, and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-blood-pressure\/\"><span style=\"font-weight: 400;\">hypotension<\/span><\/a><span style=\"font-weight: 400;\"> (low blood pressure). In turn, low blood pressure can cause symptoms such as lightheadedness, fatigue, and irregular heartbeat.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other<\/span> <a href=\"https:\/\/nctr-crs.fda.gov\/fdalabel\/services\/spl\/set-ids\/24837d82-0f3f-4482-9af0-31e5f675c30f\/spl-doc?hl=metoprolol\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> in adults of all ages may include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shortness of breath, especially on exertion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bradycardia (slow heart rate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itchiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Older adults may have a<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532923\/\"><span style=\"font-weight: 400;\">higher sensitivity to metoprolol<\/span><\/a><span style=\"font-weight: 400;\"> because<\/span> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC1884487\/\"><span style=\"font-weight: 400;\">drug metabolism changes<\/span><\/a><span style=\"font-weight: 400;\"> with age. For some older adults, this could increase the risk of side effects or make them more pronounced. Because<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK574550\/\"><span style=\"font-weight: 400;\">50% of older adults<\/span><\/a><span style=\"font-weight: 400;\"> take more than one prescription medication, older adults may also have a higher risk of metoprolol interacting with another drug.\u00a0<\/span><\/p>\n<h2 id=\"serious-side-effects-of-metoprolol-in-older-adults\"><span style=\"font-weight: 400;\">Serious side effects of metoprolol in older adults<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some of the serious side effects of metoprolol are especially dangerous for older adults, although they should be recognized by anyone taking this medication. Serious <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metoprolol-side-effects\"><span style=\"font-weight: 400;\">metoprolol side effects<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Worsening of cardiovascular conditions, such as heart failure or angina<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dangerously slow heartbeat (severe bradycardia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart block<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiac arrest or heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wheezing (bronchospasm)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Allergic reactions (e.g., swelling of the face, trouble breathing, and hives)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">For older adults, even common side effects of metoprolol can become serious or cause further complications. This is particularly true if the patient has another health condition that causes physical weakness or a cognitive condition such as<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/alzheimers-dementia-medication-management\/\"><span style=\"font-weight: 400;\">dementia or Alzheimer\u2019s disease<\/span><\/a><span style=\"font-weight: 400;\">. For instance, fatigue and dizziness can increase the<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/fall-prevention-for-seniors\/\"><span style=\"font-weight: 400;\">risk of falls<\/span><\/a><span style=\"font-weight: 400;\">. Diarrhea also increases the risk of dehydration, which is already<\/span> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10255140\/\"><span style=\"font-weight: 400;\">more common in older patients<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finally, metoprolol is a beta blocker, and other beta blockers have been associated with<\/span> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7306637\/\"><span style=\"font-weight: 400;\">central nervous system (CNS) side effects<\/span><\/a><span style=\"font-weight: 400;\">. \u201cMetoprolol can contribute to confusion, fatigue, slowed thinking, or<\/span> <a href=\"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.neuropsych.11100240\"><span style=\"font-weight: 400;\">memory issues<\/span><\/a><span style=\"font-weight: 400;\"> in some older adults,\u201d says Stefanie Diaz, MD, a board-certified nephrologist at the<\/span> <a href=\"https:\/\/ckcdocs.com\/providers\/\"><span style=\"font-weight: 400;\">Center for Kidney Care<\/span><\/a><span style=\"font-weight: 400;\"> and teaching faculty at<\/span> <a href=\"https:\/\/www.uttyler.edu\/directory\/nephrology\/stefanie-diaz.php\"><span style=\"font-weight: 400;\">the University of Texas at Tyler School of Medicine<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2 id=\"metoprolol-special-precautions-in-older-adults\"><span style=\"font-weight: 400;\">Metoprolol special precautions in older adults<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Metoprolol is generally considered safe, even in older adults. However, adults with multiple health conditions or who are taking various medications have an increased risk of side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Here are some special precautions to consider for older adults on metoprolol.<\/span><\/p>\n<h3 id=\"1-share-your-health-history-with-your-doctor-before-taking-metoprolol\"><span style=\"font-weight: 400;\">1. Share your health history with your doctor before taking metoprolol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Metoprolol is not right for everyone. It\u2019s important to share your complete medical history, including current symptoms, current and previous health conditions, as well as medications and supplements you\u2019re taking, before starting any new prescription medication.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, the drug label information states that though there have been no studies on metoprolol use in people with liver disease, there is a possibility of complications in people with poor liver function. The label also states that metoprolol can cause, or potentially worsen, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/erectile-dysfunction-treatment-and-medications\"><span style=\"font-weight: 400;\">erectile dysfunction<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"2-understand-that-metoprolol-can-interact-with-other-drugs\"><span style=\"font-weight: 400;\">2. Understand that metoprolol can interact with other drugs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Older adults are more likely than younger adults to be taking multiple prescription medications, over-the-counter medications, and supplements. However, some of these drugs may interact with metoprolol treatment.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/metoprolol-interactions\/\"><span style=\"font-weight: 400;\">Metoprolol drug interactions<\/span><\/a><span style=\"font-weight: 400;\"> to be aware of\u00a0 in patients of all ages include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Monoamine oxidase inhibitors (MAOIs) such as Azilect (rasagiline), Emsam (selegiline), and Marplan (isocarboxazid)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">Antidepressants<\/span><\/a><span style=\"font-weight: 400;\"> such as Paxil (paroxetine), Wellbutrin (bupropion), Proz<\/span><span style=\"font-weight: 400;\">ac (fluoxetine)<\/span><span style=\"font-weight: 400;\">, and Zoloft (sertraline)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antipsychotics such as haloperidol or chlorpromazine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain<\/span> <a href=\"https:\/\/www.singlecare.com\/drug-classes\/calcium-channel-blockers\"><span style=\"font-weight: 400;\">calcium channel blockers<\/span><\/a><span style=\"font-weight: 400;\">, such as verapamil or Cardizem (diltiazem)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Metoprolol can also increase the risk of low blood sugar (hypoglycemia) and diminish warning signs of low blood sugar. Because of that, metoprolol use can impact the effects of<\/span> <a href=\"https:\/\/www.singlecare.com\/drug-classes\/insulins\"><span style=\"font-weight: 400;\">insulin<\/span><\/a><span style=\"font-weight: 400;\">,<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/metformin\/what-is\"> <span style=\"font-weight: 400;\">metformin<\/span><\/a><span style=\"font-weight: 400;\">, and other antidiabetic drugs. Older adults should seek medical advice from their healthcare provider to determine whether their diabetes medication dosage should be adjusted while taking metoprolol.<\/span><\/p>\n<h3 id=\"don-t-stop-taking-metoprolol-suddenly\"><span style=\"font-weight: 400;\">Don\u2019t stop taking metoprolol suddenly<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">It\u2019s important to know that metoprolol and other beta blockers carry a black box warning (also called a boxed warning) about the risk of sudden discontinuation. The Food and Drug Administration has associated sudden withdrawal with rebound symptoms that can significantly increase the risk of cardiovascular events such as a heart attack.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Hence, you should not stop metoprolol abruptly or without the guidance of a healthcare professional.<\/span><\/p>\n<h3 id=\"alert-a-healthcare-professional-to-any-adverse-effects-after-a-dose-adjustment\"><span style=\"font-weight: 400;\">Alert a healthcare professional to any adverse effects after a dose adjustment<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u201cThere isn\u2019t one universal safe dose. It must be individualized,\u201d Dr. Diaz says. \u201cBut the safest approach is always to start on a low dose and titrate up the dose as tolerated. The clinician will adjust the dose based on the blood pressure, heart rate, and symptoms.\u201d<\/span><\/p>\n<h3 id=\"regularly-monitor-for-side-effects\"><span style=\"font-weight: 400;\">Regularly monitor for side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u201cIt is important to monitor closely for side effects: memory loss, low blood pressure, allergic reactions as well,\u201d says <\/span><a href=\"http:\/\/www.linkedin.com\/in\/jennifer-armendariz-649593170\"><span style=\"font-weight: 400;\">\u00a0<\/span><span style=\"font-weight: 400;\">Jennifer L. Armendariz, AOCNP<\/span><\/a><span style=\"font-weight: 400;\">, a family nurse practitioner and hematology\/oncology specialist in El Paso, Texas. She points out that some metoprolol side effects, like fatigue and memory loss, can be overlooked \u201cas just part of the aging process.\u201d If an older adult on metoprolol starts experiencing new symptoms, it\u2019s essential to pay attention and report them to a healthcare professional.\u00a0<\/span><\/p>\n<h2 id=\"how-to-manage-and-monitor-metoprolol-side-effects-in-older-adults\"><span style=\"font-weight: 400;\">How to manage and monitor metoprolol side effects in older adults<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Metoprolol side effects don\u2019t always occur, as everyone responds differently to medication. There are also ways to prevent metoprolol side effects. Tips for older adults include the following:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Take it at the same time(s) every day.<\/b> <a href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate\/dosage\"><span style=\"font-weight: 400;\">Metoprolol succinate<\/span><\/a><span style=\"font-weight: 400;\"> is taken once per day, whereas <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-tartrate\/dosage\"><span style=\"font-weight: 400;\">metoprolol tartrate<\/span><\/a><span style=\"font-weight: 400;\"> is taken twice or three times daily, depending on the reason for taking it. Taking your medication at the same time(s) every day can help maintain steady levels in your body, reducing the risk of sudden side effects.<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Start with a low dose of metoprolol. <\/b><span style=\"font-weight: 400;\">Though beta blockers are often beneficial for cardiovascular health, Dr. Diaz says healthcare providers take a more cautious approach, starting at lower doses for older adults.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Track blood pressure.<\/b><span style=\"font-weight: 400;\"> &#8220;Patients and caregivers should be educated to monitor blood pressures at home and to keep a blood pressure log,&#8221; Armendariz says.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Report symptoms early. <\/b><span style=\"font-weight: 400;\">Tell your provider right away if you notice new or worsening side effects of metoprolol. Your dosage might need to be decreased.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Attend regular check-ups. <\/b><span style=\"font-weight: 400;\">Both Drs. Diaz and Armendariz emphasize the importance of monitoring the health of older adults on metoprolol. Patients should do their best to keep appointments with their provider and not hesitate to schedule additional check-ups if side effects develop.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Avoid sudden discontinuation. <\/b><span style=\"font-weight: 400;\">&#8220;Metoprolol should not be stopped abruptly,&#8221; Armendariz reminds. &#8220;If this medication is stopped abruptly, the risk of increased chest pain or even a heart attack can occur.&#8221; When abruptly discontinued, a patient\u2019s heart rate can shoot up, a condition called tachycardia.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>If you miss a dose, take the next dose as soon as possible. <\/b><span style=\"font-weight: 400;\">However, don\u2019t ever double your dosage. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule.\u00a0\u00a0<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">Ultimately, older adults and their caregivers need to stay alert to possible metoprolol side effects. &#8220;When used thoughtfully, beta blockers are an important tool in heart health and longevity and can be both safe and beneficial in older adults,&#8221; Dr. Diaz says.<\/span><\/p>\n<h2 id=\"frequently-asked-questions-about-metoprolol-use-in-older-adults\"><span style=\"font-weight: 400;\">Frequently asked questions about metoprolol use in older adults<\/span><\/h2>\n<h3 id=\"can-metoprolol-cause-confusion-or-memory-loss-in-older-adults\"><span style=\"font-weight: 400;\">Can metoprolol cause confusion or memory loss in older adults?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Yes, metoprolol may cause confusion or memory loss in older adults, especially if they are dehydrated or are on other medications, according to Dr. Diaz. However, these are not common side effects.\u00a0<\/span><\/p>\n<h3 id=\"what-is-the-safest-metoprolol-dosage-for-older-adults\"><span style=\"font-weight: 400;\">What is the safest metoprolol dosage for older adults?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There is no one-size-fits-all safest metoprolol dosage for older adults. Dr. Armendariz says the safest dose is the lowest possible that achieves the medication&#8217;s intended effects. It is best to start low and titrate upward as advised by your healthcare provider.<\/span><\/p>\n<h3 id=\"should-older-adults-avoid-beta-blockers\"><span style=\"font-weight: 400;\">Should older adults avoid beta blockers?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Not necessarily. Dr. Diaz suggests that, rather than avoiding beta blockers altogether, older adults might need to start at lower doses. Older adults and their caregivers should also be educated to carefully monitor for side effects, per Dr. Armendariz.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metoprolol is a generic prescription drug, available as brand-name Lopressor, that is prescribed for hypertension, angina pectoris (chest pain from reduced cardiac blood flow), and myocardial infarction (when blood flow to part of the heart is severely reduced, causing damage to the heart). Healthcare providers may also prescribe either metoprolol tartrate or metoprolol succinate for [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":635047,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[737,12752],"coauthors":[8861],"class_list":["post-635046","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-heart-health","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Metoprolol side effects elderly patients should know about<\/title>\n<meta name=\"description\" content=\"Metoprolol side effects elderly adults should know about include fatigue, dizziness, headaches, and low blood pressure. 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