{"id":635284,"date":"2026-02-24T09:30:54","date_gmt":"2026-02-24T14:30:54","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=635284"},"modified":"2026-02-18T16:31:51","modified_gmt":"2026-02-18T21:31:51","slug":"does-prednisone-make-you-hungry","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/does-prednisone-make-you-hungry\/","title":{"rendered":"Does prednisone make you hungry?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/blog\/methylprednisolone-vs-prednisone\/\"><span style=\"font-weight: 400;\">Steroid medications<\/span><\/a><span style=\"font-weight: 400;\">, also known as corticosteroids or glucocorticoids, are used for both short- and long-term treatment of many health conditions. One of the most common is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">prednisone<\/span><\/a><span style=\"font-weight: 400;\">, a prescription medication that is used to treat a variety of inflammatory and immune-related disorders, like rheumatoid arthritis and allergic conditions such as contact dermatitis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like any medication, there are potential side effects of prednisone. One of the most frequently reported is feeling hungrier than usual. Here, discover exactly why that is, plus other ways prednisone can impact your metabolism, and what you can do to stay in control.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Prednisone with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tPrednisone 20 mg (10 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.15<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.15<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone#blog-cta\" class=\"coupon-see-all-btn\">See Prednisone prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"why-does-prednisone-make-you-hungry\"><span style=\"font-weight: 400;\">Why does prednisone make you hungry?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cWhile prednisone is a cornerstone for treatment of multiple diseases, it is associated with side effects such as increased appetite,\u201d says <\/span><a href=\"https:\/\/www.binghamton.edu\/pharmacy-and-pharmaceutical-sciences\/academics\/departments\/pharmacy-practice\/profile.html?id=twarner1\"><span style=\"font-weight: 400;\">Taylor Clark, Pharm.D.<\/span><\/a><span style=\"font-weight: 400;\">, a clinical assistant professor at Binghamton University School of Pharmacy and Pharmaceutical Sciences. This is mainly due to its effect on certain hormones that make you feel hungrier.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prednisone acts on several hormones that play a role in appetite:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Cortisol: <\/b><span style=\"font-weight: 400;\">\u201cPrednisone mimics cortisol, a natural stress hormone that plays a role in appetite regulation and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/what-foods-lower-blood-sugar-immediately\/\"><span style=\"font-weight: 400;\">blood sugar balance<\/span><\/a><span style=\"font-weight: 400;\">,\u201d says <\/span><a href=\"https:\/\/www.gutsygirlmd.com\/about\"><span style=\"font-weight: 400;\">Supriya Rao, MD<\/span><\/a><span style=\"font-weight: 400;\">, a gastroenterologist based in Lowell, Massachusetts. <\/span><a href=\"https:\/\/www.health.harvard.edu\/staying-healthy\/why-stress-causes-people-to-overeat\"><span style=\"font-weight: 400;\">High cortisol levels<\/span><\/a><span style=\"font-weight: 400;\"> can increase appetite and the motivation to eat.<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Leptin: <\/b><span style=\"font-weight: 400;\">\u201cGlucocorticoids [such as prednisone] in excess decrease the effect of leptin on appetite suppression,\u201d Dr. Clark notes. \u201cLeptin, a hormone derived from adipose tissue, acts as a sensor for fat stores. Thus, when it is low, appetite increases, but when it is high, appetite decreases.\u201d In other words, you might still feel hungry even when your body has had enough because prednisone makes it harder for your body to notice its natural fullness indicators.<\/span><\/li>\n<li aria-level=\"1\"><b>Insulin: <\/b><span style=\"font-weight: 400;\">Prednisone can also disrupt insulin signaling, the process by which glucose is transported into cells for energy, potentially leading to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ozempic-for-insulin-resistance\/\"><span style=\"font-weight: 400;\">insulin resistance<\/span><\/a><span style=\"font-weight: 400;\">. \u201cInsulin resistance prevents absorption of blood sugar into the cells, which leads to a starvation state despite high sugar content in the blood, which causes signals of continued hunger,\u201d Dr. Clark says.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">High blood sugar levels can cause spikes in hunger and sudden drops that trigger additional hunger and cravings, adds Dr. Rao. One <\/span><a href=\"https:\/\/e-enm.org\/journal\/view.php?number=2476\"><span style=\"font-weight: 400;\">review<\/span><\/a><span style=\"font-weight: 400;\"> found that a third of people taking glucocorticoids like prednisone develop insulin resistance and high blood sugar. \u201cThis means your body might have a harder time using glucose efficiently,\u201d Dr. Rao says. \u201cIt can also promote fat storage over time and make weight changes more likely even without major changes in your calorie intake.\u201d<\/span><\/p>\n<h2 id=\"prednisone-s-impact-on-your-body-and-weight\"><span style=\"font-weight: 400;\">Prednisone\u2019s impact on your body and weight<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If prednisone makes you feel hungrier, you might eat more calories than you need while taking it, leading to weight gain. That\u2019s not the only effect it can have on your waistline. It can cause body weight changes in the following ways:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Increased fluid retention:<\/b><span style=\"font-weight: 400;\">\u00a0 \u201cPrednisone and other corticosteroids can lead to sodium retention, which often leads to fluid retention,\u201d Dr. Clark says. This can cause uncomfortable bloating and swelling, and potentially lead to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/weight-gain-in-women-causes\/\"><span style=\"font-weight: 400;\">weight gain<\/span><\/a><span style=\"font-weight: 400;\"> from water weight.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Changes in fat distribution: <\/b><span style=\"font-weight: 400;\">Prednisone can also lead to fat redistribution, causing fullness in your face or upper body, Dr. Rao explains.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Reduced muscle mass:<\/b><span style=\"font-weight: 400;\"> \u201cWith long-term use, it can break down muscle tissue, which reduces lean muscle mass and can slow metabolism.\u201d\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Prednisone can also negatively affect your sleep, mood, and bone health, all of which can indirectly contribute to unwanted weight gain if you don\u2019t take steps to counteract the changes.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/academic.oup.com\/jcem\/article\/110\/12\/e3989\/8121022\"><span style=\"font-weight: 400;\">One study<\/span><\/a> <span style=\"font-weight: 400;\">found that people who took corticosteroids experienced significantly more weight gain over the study period than those who didn\u2019t take the medications, especially people who were taking the drugs for the first time. However, this weight gain was modest, less than one kilogram (2.2 pounds) per year.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"practical-strategies-to-stay-in-control\"><span style=\"font-weight: 400;\">Practical strategies to stay in control<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Dr. Clark notes that for some people, weight gain may be an intended result or positive side effect of taking prednisone. But for others who don\u2019t want to overeat, there are things they can do. The first is to remember that your increased appetite is really all in your head. \u201cThe impact appears to be mostly on perceptions of feeling hunger rather than a physiologic need for increased calories while taking corticosteroids,\u201d Dr. Clark explains. For this reason, tricks like drinking water or distracting yourself with another activity may be enough to avoid snacking.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Beyond that, experts suggest the following strategies for managing hunger and avoiding unwanted weight gain:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Eat small, frequent meals<\/b><span style=\"font-weight: 400;\"> that include protein, fiber, and healthy fats to support satiety.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Follow a set eating schedule <\/b><span style=\"font-weight: 400;\">to avoid snacking and grazing, especially on carbohydrate-rich foods.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Reduce excess sodium intake <\/b><span style=\"font-weight: 400;\">to limit water retention.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Drink plenty of water<\/b><span style=\"font-weight: 400;\"> so you don\u2019t mistake thirst for hunger.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Aim for at least 150 minutes of moderate physical activity per week, <\/b><span style=\"font-weight: 400;\">including resistance and strength training. Regular exercise can help to maintain metabolism and muscle mass. It can also help with weight loss when you discontinue the medication.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you need to take prednisone long-term, Dr. Rao says that one of the best things you can do is to prepare yourself mentally. \u201cSet expectations because some appetite and weight changes may be unavoidable if the medication is necessary,\u201d she explains.\u00a0<\/span><\/p>\n<h2 id=\"when-to-talk-to-your-healthcare-provider\"><span style=\"font-weight: 400;\">When to talk to your healthcare provider<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">All that said, if you feel like your appetite is out of control while taking prednisone, don\u2019t hesitate to seek medical advice from your healthcare provider. \u201cTalk to your doctor if you notice rapid weight gain, swelling, mood changes, or if you feel like your side effects are impacting your quality of life or overall well-being,\u201d Dr. Rao says. Drs. Clark and Rao both note that higher doses and longer durations are associated with more pronounced side effects, so it never hurts to talk to your provider about a dose adjustment. If that\u2019s not possible, they may be able to connect you with a dietitian who can work with you to create a personalized eating plan.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Steroid medications, also known as corticosteroids or glucocorticoids, are used for both short- and long-term treatment of many health conditions. One of the most common is prednisone, a prescription medication that is used to treat a variety of inflammatory and immune-related disorders, like rheumatoid arthritis and allergic conditions such as contact dermatitis.\u00a0 Like any medication, [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":635362,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12752,8905,9825],"coauthors":[20980],"class_list":["post-635284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-medication-side-effects","tag-seasonal","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Does prednisone make you hungry? Here\u2019s the truth<\/title>\n<meta name=\"description\" content=\"Prednisone is a corticosteroid that may increase your appetite and cravings. 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