{"id":635475,"date":"2026-03-13T09:30:59","date_gmt":"2026-03-13T13:30:59","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=635475"},"modified":"2026-03-25T14:52:13","modified_gmt":"2026-03-25T18:52:13","slug":"why-cant-you-have-caffeine-with-farxiga","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/why-cant-you-have-caffeine-with-farxiga\/","title":{"rendered":"Can you drink coffee while taking Farxiga?"},"content":{"rendered":"

For many Americans, coffee is a daily ritual. So when you\u2019re prescribed a new medication, one of the first questions that comes to mind is whether your morning cup is still okay. If you\u2019re taking Farxiga, you may be wondering how caffeine fits into the picture.<\/span><\/p>\n

Farxiga<\/span><\/a> (dapagliflozin) is commonly prescribed to treat Type 2 diabetes and is also FDA approved to help slow the progression of heart failure and chronic kidney disease. While caffeine doesn\u2019t directly interact with the medication, both can affect hydration, blood sugar, and blood pressure. For most people, moderate caffeine intake is safe, but some may need to cut back or take extra precautions. Here\u2019s what to know before you brew your next cup.<\/span><\/p>\n\t\t

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\n\t\t\t\t\tFarxiga 10 mg (30 tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23663 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
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\n\t\t\t\"Food\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$40.70\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
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\n\t\t\t\"CVS\t\t\t<\/div>\n\t\t\t
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\n\t\t\t\t\t$207.43\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Farxiga prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

How caffeine might interact with Farxiga<\/span><\/h2>\n

\u201cFarxiga does not directly interact with caffeine,\u201d says <\/span>Talia Wall, Pharm.D.<\/span><\/a>, an assistant professor of pharmacy practice at Touro College of Pharmacy in New York, New York. \u201cBut Farxiga and caffeine may have similar effects on the body. They both contribute to increased urine output.\u201d So, taking them together may increase the risk of changes in blood sugar, low blood pressure, or dehydration. These are the three biggest ways that mixing caffeine and Farxiga may contribute to negative side effects.<\/span><\/p>\n

1. Blood sugar fluctuations<\/span><\/h3>\n

\u201cFarxiga [a sodium-glucose cotransporter-2 (SGLT2) inhibitor] already works to decrease blood glucose on its own by pushing excess glucose out of the body through the urinary tract,\u201d explains <\/span>Carrie Kreps, Pharm.D.<\/span><\/a>, the director of clinical services at Pharmacy Care Associates, an independent specialty retail pharmacy in Montgomery, Alabama. She says that strictly mixing caffeine with Farxiga does not have a direct impact on blood sugar for everyone, but it could cause fluctuations depending on a few factors.<\/span><\/p>\n

\u201cIn someone with diabetes who is taking insulin, caffeine can potentially increase <\/span>insulin resistance<\/span><\/a> or impair the way that the body responds to insulin, creating an opposite effect than desired by Farxiga use,\u201d Dr. Wall says. \u201cAt the same time, caffeine may enhance the ability of Farxiga to remove glucose from the body via the urine as it has a similar effect on the body, and this would contribute to lower blood sugar levels.\u201d In other words, if you\u2019re taking Farxiga for Type 2 diabetes and struggling to get your blood sugar under control, combining it with caffeine could make that a little more difficult.<\/span><\/p>\n

Dr. Kreps adds that if you typically get your caffeine from a sugary coffee or energy drink, the added carbohydrates in your drink could affect your blood sugar.\u00a0<\/span><\/p>\n

2. Blood pressure tug-of-war<\/span><\/h3>\n

\u201cIt\u2019s reasonable to expect blood pressure to slightly drop when taking Farxiga alone because of how it works [by increasing urine output],\u201d Dr. Kreps says. But when you drink coffee, you may experience some fluctuations. \u201cAdding caffeine consumption while taking Farxiga may offset the decrease in blood pressure initially, because caffeine can initially increase blood pressure,\u201d Dr. Kreps explains. \u201cAnd then after, it causes mild diuresis, which could possibly decrease blood pressure in sensitive demographics.\u201d\u00a0<\/span><\/p>\n

3. Hydration changes<\/span><\/h3>\n

Since Farxiga and caffeine both increase how much you go to the bathroom, they can increase the likelihood of dehydration. But as long as you\u2019re taking steps to drink enough water, it shouldn\u2019t be an issue. \u201cMixing Farxiga and caffeine may cause dehydration, but caffeine doesn’t necessarily need to be avoided if a patient maintains adequate fluid intake,\u201d Dr. Wall says.<\/span><\/p>\n

What the research says<\/span><\/h2>\n

There are not many scientific studies examining the effects of combining Farxiga and caffeine, but the few that exist have reached the same conclusions. When treatment with Farxiga is started, it can cause a slight worsening in kidney function. Even so, for the long term, Farxiga helps slow the decline in kidney function after what is called the initial \u201cdip\u201d. Two studies from Saint Louis University, one published in the <\/span>Journal of the American Society of Nephrology<\/span><\/i><\/a> and the other published in <\/span>Physiological Reports<\/span><\/i><\/a> showed that caffeine in large quantities may help offset the \u201cdip\u201d in kidney function that is seen when patients are started on Farxiga.<\/span><\/p>\n

However, these were both retrospective survey-style studies that relied on people self-reporting their caffeine intake, both of which are limitations that would need to be addressed in future research into how caffeine may impact the effects of Farxiga on kidney function.<\/span><\/p>\n

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