{"id":635503,"date":"2026-03-05T09:59:29","date_gmt":"2026-03-05T14:59:29","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=635503"},"modified":"2026-03-05T11:57:58","modified_gmt":"2026-03-05T16:57:58","slug":"is-20-mg-of-lisinopril-a-high-dose","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/is-20-mg-of-lisinopril-a-high-dose\/","title":{"rendered":"Is 20 mg of lisinopril a high dose?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril\"><span style=\"font-weight: 400;\">Lisinopril<\/span><\/a><span style=\"font-weight: 400;\"> is a prescription medication used to control high blood pressure in people 6 years and older. This drug is an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ace-inhibitors\"><span style=\"font-weight: 400;\">angiotensin-converting enzyme (ACE) inhibitor<\/span><\/a><span style=\"font-weight: 400;\">, a class of drugs recommended by the American Heart Association (AHA) and American College of Cardiology (ACC) as a first-line drug choice for hypertension (high blood pressure). Lisinopril is also approved by the Food and Drug Administration (FDA) to treat heart failure and to improve survival after a heart attack. Healthcare providers may recommend a certain dose of lisinopril based on your condition and various other factors. We\u2019ll explain what\u2019s considered a high dose of lisinopril and its safety and side effect profile.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Lisinopril with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. 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Lisinopril is available in the following doses:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oral tablets: 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg, 40 mg<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Oral solution (liquid): 1 mg\/mL<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">For adults, the typical dosage is between 10 to 40 mg daily. In children 6 years and older, the dosage depends on the child\u2019s weight.\u00a0<\/span><\/p>\n<h3 id=\"typical-starting-dose-of-lisinopril\"><span style=\"font-weight: 400;\">Typical starting dose of lisinopril<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The typical starting dosage of lisinopril can range from 2.5 mg to 10 mg, depending on what it\u2019s being prescribed for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">For adults with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/hypertension-treatments-and-medications\"><span style=\"font-weight: 400;\">high blood pressure<\/span><\/a><span style=\"font-weight: 400;\">, the 2025 AHA\/ACC guidelines recommend starting at 10 mg per day.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with heart failure are recommended to start at 2.5 mg of lisinopril daily, according to the <\/span><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIR.0000000000001063\"><span style=\"font-weight: 400;\">2022 AHA\/ACC\/Heart Failure Society of America (HFSA) guidelines<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Within 24 hours of a heart attack, lisinopril may be recommended starting at 2.5 to 5 mg daily.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In patients with kidney disease, the initial dose of lisinopril is typically lower, depending on their creatinine clearance rate.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">For children 6 years and older, the starting dose is 0.07 mg\/kg (maximum 5 mg per dose) once daily. The maximum dose is 0.6 mg\/kg\/day, or up to 40 mg daily.\u00a0\u00a0<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/welzo.com\/pages\/dr-blen-tesfu\"><span style=\"font-weight: 400;\">Blen Tesfu<\/span><\/a><span style=\"font-weight: 400;\">, MD, a physician and medical adviser at Welzo, explains, \u201cThe majority of patients with elevated blood pressure are prescribed lisinopril at an initial dosage of 5\u201310 mg, once daily. This lower starting point is used to allow for the body&#8217;s adaptation to the new drug, as well as for the provider to evaluate the patient&#8217;s tolerance of the new medication.\u201d Then, depending on the patient\u2019s response to the medication, lisinopril \u201cmay be gradually increased in small increments over time,\u201d she says. The dose should only be adjusted by the healthcare provider.\u00a0<\/span><\/p>\n<h3 id=\"typical-maintenance-dose-of-lisinopril\"><span style=\"font-weight: 400;\">Typical maintenance dose of lisinopril<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The typical maintenance dose of lisinopril is 10\u201340 mg daily, depending on how you respond to the medication and whether you experience any side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For high blood pressure, the usual dosage is 10\u201340 mg daily. If your blood pressure isn\u2019t controlled with lisinopril alone, your healthcare provider may add on a low-dose <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/diuretics\"><span style=\"font-weight: 400;\">diuretic<\/span><\/a><span style=\"font-weight: 400;\"> (water pill) such as hydrochlorothiazide. In this case, your healthcare provider may reduce your dose of lisinopril to 5 mg daily.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">After a heart attack, your healthcare provider may recommend 5 mg lisinopril within 24 hours, then 5 mg after 24 hours and increase it to 10 mg after 48 hours, then 10 mg once daily for at least six weeks. People with low systolic blood pressure may be started on a lower dose of 2.5 mg.<\/span><\/p>\n<h3 id=\"max-lisinopril-dosage\"><span style=\"font-weight: 400;\">Max lisinopril dosage<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">\u201cIf you have high blood pressure that needs to be controlled because it is caused by other diseases like heart failure, or if your doctor feels that your blood pressure needs to be controlled more aggressively, then a higher dose of lisinopril may be necessary,\u201d says <\/span><a href=\"https:\/\/medicalcert.co.uk\/about\/drmariaknobel\/\"><span style=\"font-weight: 400;\">Maria Knobel<\/span><\/a><span style=\"font-weight: 400;\">, MBBS, physician and medical director of Medical Cert UK.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lisinopril can be taken up to 40 mg daily for adults and children over 6 years old. Though doses of up to 80 mg daily have been used in people with high blood pressure, there was no further benefit compared to taking 40 mg of lisinopril daily.\u00a0<\/span><\/p>\n<h2 id=\"is-20-mg-of-lisinopril-a-high-dose\"><span style=\"font-weight: 400;\">Is 20 mg of lisinopril a high dose?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">No, 20 mg of lisinopril isn\u2019t considered a high dose. Though 20 mg is more than the recommended starting dose for the drug, it\u2019s not the maximum recommended dosage, either. This dosage is within the usual 10 to 40 mg dosage that could be recommended. \u201cA 20 mg daily dosage of lisinopril would be classified as moderate in terms of dosage rather than high, as it falls well within the commonly accepted dosages of medication to treat hypertension,\u201d Dr. Tesfu says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Healthcare providers may increase your dose of lisinopril from the initial dose based on how you tolerate the drug and how well your symptoms are controlled.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th class=\"title\" role=\"columnheader\" scope=\"col\">\n<h2 id=\"lisinopril-dosage-chart\"><span class=\"title\">\u00a0 Lisinopril dosage chart<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Condition<\/b><\/td>\n<td><b>Starting dose<\/b><\/td>\n<td><b>Maintenance dose<\/b><\/td>\n<td><b>Maximum dose<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>High blood pressure (adults)<\/b><\/td>\n<td><span style=\"font-weight: 400;\">10 mg daily<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10\u201340 mg daily<\/span><\/td>\n<td rowspan=\"5\"><span style=\"font-weight: 400;\">40 mg daily<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Heart failure in adults<\/b><\/td>\n<td><span style=\"font-weight: 400;\">2.5 or 5 mg daily<\/span><\/td>\n<td rowspan=\"3\"><span style=\"font-weight: 400;\">20\u201340 mg daily<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>People with kidney disease<\/b><\/td>\n<td><span style=\"font-weight: 400;\">2.5 mg or 5 mg daily, depending on creatinine clearance and whether you are on dialysis<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>High blood pressure (children 6 years and older)<\/b><\/td>\n<td><span style=\"font-weight: 400;\">0.07 mg\/kg once daily, up to 5 mg daily<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Heart attack in adults<\/b><\/td>\n<td><span style=\"font-weight: 400;\">2.5\u20135 mg daily, starting within 24 hours<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10 mg daily\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"is-20-mg-of-lisinopril-safe\"><span style=\"font-weight: 400;\">Is 20 mg of lisinopril safe?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Yes. Generally, 20 mg of lisinopril is safe when taken as prescribed by a healthcare provider. This dose is within the range of usual doses of lisinopril listed on its drug label. If you experience new or worsening symptoms while taking lisinopril, contact your healthcare provider to investigate so they can adjust your treatment as needed.\u00a0<\/span><\/p>\n<h2 id=\"possible-lisinopril-side-effects-and-warnings\"><span style=\"font-weight: 400;\">Possible lisinopril side effects and warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lisinopril comes with a risk of side effects and warnings to be aware of. Common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/lisinopril-side-effects\/\"><span style=\"font-weight: 400;\">side effects of lisinopril<\/span><\/a><span style=\"font-weight: 400;\"> include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/hyperkalemia-symptoms\"><span style=\"font-weight: 400;\">High potassium levels<\/span><\/a><span style=\"font-weight: 400;\"> (hyperkalemia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Though there aren\u2019t many clinical trials that suggest whether doses affect the risks of side effects, <\/span><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/01.cir.100.23.2312\"><span style=\"font-weight: 400;\">one study in subjects with heart failure<\/span><\/a><span style=\"font-weight: 400;\"> taking a higher dose of lisinopril (32.5\u201335 mg daily) experienced more dizziness and kidney function changes compared to subjects taking a lower dose (2.5\u20135 mg daily) of the drug. \u201cAs doses [of lisinopril] become larger, healthcare professionals will check a patient&#8217;s kidneys and their potassium levels much more closely. This will assist in ensuring that the medication is both safe and effective for the patient,\u201d Dr. Tesfu shares.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are some serious side effects and warnings around taking lisinopril to keep in mind. First, people who are pregnant should not take lisinopril. The medication has a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\"> for fetal toxicity, meaning taking lisinopril during pregnancy can cause harm to the developing fetus.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other serious side effects of lisinopril include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Head and neck swelling (angioedema)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anaphylactic reactions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Impaired kidney function, possibly causing kidney failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension), which can cause fainting, dizziness, or death<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood potassium (hyperkalemia), which can cause heart rhythm changes, muscle weakness, and numbness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver failure<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These serious side effects require immediate medical attention. Call emergency medical services and talk to your healthcare provider as soon as possible if you notice any signs or symptoms of these serious side effects.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK430896\/\"><span style=\"font-weight: 400;\">ACE inhibitors<\/span><\/a><span style=\"font-weight: 400;\">, including lisinopril, may interact with other medications and substances, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diuretics such as furosemide, hydrochlorothiazide, or <\/span><span style=\"font-weight: 400;\">spironolactone<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antidiabetic medications, such as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/insulins\"><span style=\"font-weight: 400;\">insulins<\/span><\/a><span style=\"font-weight: 400;\">, which can lower blood sugar to an unsafe level (hypoglycemia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Non-steroidal anti-inflammatory drugs (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">), such as Advil (ibuprofen) and Aleve (naproxen), which can compound with lisinopril\u2019s effects to impair kidney function, especially in certain people at higher risk<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other ACE inhibitors, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/angiotensin-ii-receptor-blockers\"><span style=\"font-weight: 400;\">angiotensin receptor blockers<\/span><\/a><span style=\"font-weight: 400;\"> (ARBs) like <\/span><span style=\"font-weight: 400;\">valsa<\/span><span style=\"font-weight: 400;\">r<\/span><span style=\"font-weight: 400;\">tan<\/span><span style=\"font-weight: 400;\">, and <\/span><span style=\"font-weight: 400;\">aliskiren<\/span><span style=\"font-weight: 400;\"> (People with diabetes should never take lisinopril with aliskiren.)\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Read our article for a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/lisinopril-interactions\/\"><span style=\"font-weight: 400;\">complete list of lisinopril&#8217;s drug interactions<\/span><\/a><span style=\"font-weight: 400;\">, including how to minimize or manage them.\u00a0<\/span><\/p>\n<h2 id=\"signs-your-lisinopril-dose-is-too-high\"><span style=\"font-weight: 400;\">Signs your lisinopril dose is too high<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Even if you\u2019re not taking the maximum daily dose of 40 mg lisinopril, you still may experience side effects. Talk to your healthcare provider about adjusting your dose if you notice signs, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness, lightheadedness, or confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fainting\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart palpitations, rapid heartbeats, muscle weakness, or numbness and tingling<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased urination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Extreme drowsiness or tiredness<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u201cIf any of these symptoms occur, do not ignore them and seek immediate medical help,\u201d Dr. Knobel advises. These can be a sign that your lisinopril dose may need adjustment. Your healthcare provider can work with you to adjust your dose or find an alternative so your medication therapy is both safe and effective.\u00a0<\/span><\/p>\n<h2 id=\"final-thoughts\"><span style=\"font-weight: 400;\">Final thoughts<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although it\u2019s not considered a low dose, 20 mg of lisinopril is not considered an unusually high dose of the medication, either. Healthcare providers prescribe lisinopril based on the condition it\u2019s treating, the patient\u2019s medical history, and how the patient responds to the medication. Typical doses for lisinopril range from 10\u201340 mg daily for most indications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like any prescription medication, lisinopril comes with warnings and risks of side effects. It\u2019s important to always communicate with your healthcare professional about any new or worsening symptoms so they can tailor your treatment to reduce side effects while managing your condition.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lisinopril is a prescription medication used to control high blood pressure in people 6 years and older. This drug is an angiotensin-converting enzyme (ACE) inhibitor, a class of drugs recommended by the American Heart Association (AHA) and American College of Cardiology (ACC) as a first-line drug choice for hypertension (high blood pressure). Lisinopril is also [&hellip;]<\/p>\n","protected":false},"author":149,"featured_media":635504,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,737,20951],"coauthors":[21072],"class_list":["post-635503","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-heart-health","tag-high-blood-pressure","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Is 20 mg of lisinopril a high dose?<\/title>\n<meta name=\"description\" content=\"20 mg of lisinopril isn\u2019t considered a high dose. 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