{"id":636733,"date":"2026-06-12T17:23:04","date_gmt":"2026-06-12T21:23:04","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=636733"},"modified":"2026-06-12T17:23:04","modified_gmt":"2026-06-12T21:23:04","slug":"toprol-xl-generic","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/toprol-xl-generic\/","title":{"rendered":"Is a Toprol XL generic available?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Nearly half of all U.S. adults have high blood pressure, according to the CDC, and only one out of every four has it under control. That makes controlling hypertension with drugs like Toprol XL extremely important. As a beta blocker, it treats not only hypertension, but also angina pectoris (chest pain) and chronic heart failure, making it a versatile option in every cardiologist\u2019s arsenal. Cost-conscious patients may want to save money by using a generic version, and fortunately, they have that option.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th colspan=\"2\">\n<h2 id=\"toprol-xl-generic-availability\"><span style=\"font-weight: 400;\">Toprol XL generic availability<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><b>Generic name<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Metoprolol succinate<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>FDA approval date of the generic version<\/b><\/td>\n<td><span style=\"font-weight: 400;\">2007<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Is there a generic available for sale in the U.S.?\u00a0<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"what-are-the-differences-between-generic-and-brand-name-toprol-xl\"><span style=\"font-weight: 400;\">What are the differences between generic and brand-name Toprol XL?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Both drugs contain the same active ingredient (metoprolol) in the same strengths, dosage options, and routes of administration. Those are the FDA requirements for approving any generic drug.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cFor blood pressure control, I use metoprolol and Toprol XL interchangeably, since both are the same drug. Duration of effect is not a factor, so the best choice is generally the cheapest,\u201d says<\/span><a href=\"https:\/\/radiantmortontavel.com\/\"> <span style=\"font-weight: 400;\">Dr. Morton Tavel, MD, FACC<\/span><\/a><span style=\"font-weight: 400;\">, clinical professor emeritus (cardiology) at the Indiana University School of Medicine. That means \u201cthe generic is generally the best choice.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The biggest difference is that Toprol XL is an extended-release version, while generic metoprolol is available in both extended-release and immediate-release versions. According to<\/span><a href=\"https:\/\/manhattancardiology.com\/team\/dr-padma-shenoy\/\"> <span style=\"font-weight: 400;\">Dr. Padma Shenoy, MD<\/span><\/a><span style=\"font-weight: 400;\">, cardiologist with Manhattan Cardiology and contributor to<\/span><a href=\"https:\/\/www.labfinder.com\/\"> <span style=\"font-weight: 400;\">LabFinder<\/span><\/a><span style=\"font-weight: 400;\">. \u201cThe main difference between the two medications is the polymer that facilitates the slow release of the drug.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The extended-release version is called<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=90594d68-87f2-5f75-2d8a-1629f88ba8a9\"> <span style=\"font-weight: 400;\">metoprolol succinate<\/span><\/a><span style=\"font-weight: 400;\">, a once-daily medication commonly prescribed for long-term treatment of hypertension, angina, and chronic heart failure, as it provides<\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S3050661125000802\"> <span style=\"font-weight: 400;\">more consistent beta receptor blocking over time<\/span><\/a><span style=\"font-weight: 400;\">. Metoprolol tartrate, on the other hand, is typically taken multiple times a day, usually for conditions that require rapid adjustments in heart rate and blood pressure, such as a heart attack.<\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24247812\/\"> <span style=\"font-weight: 400;\">Some recent research<\/span><\/a><span style=\"font-weight: 400;\">, however, has shown that succinate can also be a viable option in some cases of heart attack.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other differences between brand-name and generic versions may include inactive ingredients like dyes and fillers. These typically don&#8217;t affect the body, but \u201cin rare cases, individual patients may notice a change in blood pressure or heart rate if the generic manufacturer has changed the slow-release polymer in the medication,\u201d Dr. Shenoy says. \u201cThese changes are extremely subtle, but the development of new symptoms may be a reason to transition to the brand-name Toprol XL.\u201d<\/span><\/p>\n<h2 id=\"how-much-does-generic-toprol-xl-cost\"><span style=\"font-weight: 400;\">How much does generic Toprol XL cost?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Cost is the most significant difference between most brand-name and generic drugs\u2014and Toprol XL is no different. The average price for generic metoprolol succinate is around $103 for 90, 25mg extended-release tablets, while the same amount of Toprol XL costs $161 on average.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If your healthcare provider prescribes metoprolol tartrate instead, it can be slightly more expensive. The generic version costs an average of $198 for 60, 25mg tablets, while the branded version (Lopressor) is often around $192.<\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th colspan=\"3\">\n<h3 id=\"brand-vs-generic-toprol-xl-prices\"><span style=\"font-weight: 400;\">Brand vs. generic Toprol XL prices<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Comparing costs<\/b><\/td>\n<td><b>Brand-name Toprol XL<\/b><\/td>\n<td><b>Toprol XL generic (metoprolol succinate)<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Average cost without insurance<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$161 for 90, 25mg extended-release tablets of Toprol XL<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$103 for 90, 25mg extended-release tablets of generic metoprolol succinate<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">SingleCare\u2019s lowest price<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9.11 for 90, 25mg extended-release tablets of generic Toprol XL at Kroger Pharmacy<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9.11 for 90, 25mg extended-release tablets of generic Toprol XL at Kroger Pharmacy<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Free coupons<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/toprol-xl\"><span style=\"font-weight: 400;\">Toprol XL coupons<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er\"><span style=\"font-weight: 400;\">Metoprolol succinate coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"is-toprol-xl-covered-by-insurance\"><span style=\"font-weight: 400;\">Is Toprol XL covered by insurance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some insurance plans<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metoprolol-without-insurance\/\"> <span style=\"font-weight: 400;\">cover brand-name Toprol XL<\/span><\/a><span style=\"font-weight: 400;\">, but others may prefer that you get the generic version instead, since it\u2019s usually less expensive. The only way to know for sure is to review your insurance plan\u2019s formulary to see which medication is listed as preferred.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Medicare Part D plans are similar. Some may cover Toprol XL, while others might only cover metoprolol. For example, in 2023, Medicare Part D plans paid only around $6 million nationwide in name-brand Toprol XL coverage, even though each prescription costs more, but they paid out more than $587 million worth of generic metoprolol,<\/span><a href=\"https:\/\/data.cms.gov\/summary-statistics-on-use-and-payments\/medicare-medicaid-spending-by-drug\/medicare-part-d-spending-by-drug\"> <span style=\"font-weight: 400;\">according to the Centers for Medicare &amp; Medicaid Services<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"how-do-you-get-toprol-xl-covered-by-insurance\"><span style=\"font-weight: 400;\">How do you get Toprol XL covered by insurance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you have an insurance plan that covers Toprol XL, using that coverage is as simple as presenting your insurance card at the pharmacy. But if your plan only covers generic metoprolol and you want the brand name instead, it could be more complicated.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this case, you might need to ask your prescriber to complete a prior authorization form first. This is a process insurance companies use to decide whether a particular drug is medically necessary. This may require documentation of specific symptoms, confirmation of serious side effects caused by generic metoprolol, or drug interactions, or paperwork showing that you\u2019ve tried other medications first (step therapy) and were intolerant of them or they did not work.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Additionally, if your insurance company denies coverage for Toprol XL even after a prior authorization, you can appeal that decision. The<\/span><a href=\"https:\/\/www.healthcare.gov\/appeal-insurance-company-decision\/appeals\/\"> <span style=\"font-weight: 400;\">specifics of this process<\/span><\/a><span style=\"font-weight: 400;\"> depend on the insurance company, so you\u2019ll have to check with them to find out how to file.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Metoprolol Succinate ER with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tMetoprolol Succinate ER 25 mg (90 tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.11<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$9.11<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er#blog-cta\" class=\"coupon-see-all-btn\">See Metoprolol Succinate ER prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"generic-alternatives-to-toprol-xl\"><span style=\"font-weight: 400;\">Generic alternatives to Toprol XL<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Beta blockers are a well-established drug class, and there are several generic options for anyone who has heart problems or cardiovascular conditions and needs lower blood pressure. For example, Dr. Tavel says, \u201cFor better blood pressure control, I resorted to ACE receptor blockers such as candesartan.\u201d Some of<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metoprolol-alternatives\/\"> <span style=\"font-weight: 400;\">Toprol XL\u2019s other common generic alternatives<\/span><\/a><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Other beta blockers:<\/b><span style=\"font-weight: 400;\"> atenolol, carvedilol, nebivolol, nadolol, and propranolol.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Angiotensin-converting enzyme (ACE) inhibitors:<\/b><span style=\"font-weight: 400;\"> lisinopril or lotensin.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Angiotensin II receptor blockers (ARBs):<\/b><span style=\"font-weight: 400;\"> valsartan or losartan.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Calcium channel blocking agents:<\/b><span style=\"font-weight: 400;\"> amlodipine and diltiazem.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Centrally acting alpha-agonist hypotensive agents:<\/b><span style=\"font-weight: 400;\"> clonidine.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Beta blockers like metoprolol have many uses, including ones not specifically approved by the FDA. Some healthcare providers may prescribe metoprolol for anxiety, hyperthyroidism, irregular heartbeats, or migraine prevention. Because these conditions aren\u2019t approved uses, some insurance plans might not cover metoprolol for them.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019re considering switching from Toprol XL or metoprolol to another drug, first get medical advice from a healthcare professional to see if the change is appropriate for your condition. If so, they will likely taper you off the drug, since sudden cessation of beta blocker use may<\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9724061\/\"> <span style=\"font-weight: 400;\">cause withdrawal-like symptoms<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe transition should be done under the supervision of a physician as stopping these medications can cause rebound hypertension and tachycardia,\u201d Dr. Shenoy says. This tapering typically lasts one or more weeks, depending on your dose of metoprolol, condition, and side effects. After you\u2019ve stopped taking metoprolol completely, you can begin your new medication.<\/span><\/p>\n<h2 id=\"expert-takeaway\"><span style=\"font-weight: 400;\">Expert takeaway\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cToprol XL and generic metoprolol succinate are therapeutically equivalent extended-release formulations of metoprolol. They share the same active ingredient, mechanism of action, available strengths, and dosing schedule,&#8221; says Leslie Greenberg, MD, associate professor of family and community medicine at the University of Nevada, Reno Family Medicine Residency Program. &#8220;Differences between the two medications are generally limited to inactive ingredients (like coatings, colorants, and fillers).&#8221;<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nearly half of all U.S. adults have high blood pressure, according to the CDC, and only one out of every four has it under control. That makes controlling hypertension with drugs like Toprol XL extremely important. As a beta blocker, it treats not only hypertension, but also angina pectoris (chest pain) and chronic heart failure, [&hellip;]<\/p>\n","protected":false},"author":137,"featured_media":636735,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[3418,20951],"coauthors":[21095],"class_list":["post-636733","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-generic-drugs","tag-high-blood-pressure","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Toprol XL generic availability, cost, and dosage<\/title>\n<meta name=\"description\" content=\"A Toprol XL generic is available. 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