{"id":637121,"date":"2026-08-17T09:00:22","date_gmt":"2026-08-17T13:00:22","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=637121"},"modified":"2026-08-13T23:13:27","modified_gmt":"2026-08-14T03:13:27","slug":"missed-dose-lisinopril","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/missed-dose-lisinopril\/","title":{"rendered":"What happens if you miss a dose of lisinopril?"},"content":{"rendered":"<p>Many people with high blood pressure, diabetes, or kidney disease take medications like <a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril\">lisinopril<\/a> to manage their condition. It helps <a href=\"https:\/\/www.singlecare.com\/blog\/what-is-lisinopril\/\">lower their risk of heart disease and kidney damage<\/a>, so taking it once a day is important. But what happens if you miss a dose? Though you should always try to take lisinopril as prescribed, missing one dose is usually not an emergency. The medication stays in your body for one to two days, says David Rhee, MD, with Manhattan Cardiology in NYC, so most people won&#8217;t experience serious problems after accidentally missing one dose.<\/p>\n<p>However, missing more than one dose can lead to health problems. Per Dr. Rhee, lisinopril is an angiotensin-converting enzyme (ACE) inhibitor that lowers blood pressure by blocking the production of a kidney hormone called angiotensin. When you miss two or more doses of an ACE inhibitor like lisinopril, your body begins producing more angiotensin again, and your blood pressure begins to rise. This is especially dangerous for people taking lisinopril for other FDA-approved indications, like treating heart failure or improving your survival rate after a heart attack. Here\u2019s how to catch up if you missed a dose of lisinopril, warning signs to watch for, and when to contact your healthcare provider.<\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Lisinopril with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tLisinopril 10 mg (90 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$6.76<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$6.76<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril#blog-cta\" class=\"coupon-see-all-btn\">See Lisinopril prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"what-should-you-do-if-you-miss-a-dose\">What should you do if you miss a dose?<\/h2>\n<p>Life happens, and sometimes we all forget to take a daily dose of our medication. If you miss one <a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril\/dosage\">dose of lisinopril<\/a>, don\u2019t panic. Follow this guidance instead.<\/p>\n<h3 id=\"if-it-s-been-less-than-12-hours-since-your-last-dose\">If it\u2019s been less than 12 hours since your last dose<\/h3>\n<p>You should generally always take your next dose of lisinopril as soon as you remember it, even if it\u2019s been several hours since the time you normally take it, according to <a href=\"https:\/\/www.thepharmacistsguide.com\/about\">Joanna Lewis<\/a>, Pharm.D., founder of The Pharmacist\u2019s Guide. You don\u2019t need to adjust your dosing schedule, either. You can go right back to taking it at the normal time.<\/p>\n<p><b>Example: You normally take lisinopril at 8:00 a.m., but you forget about it until 3 p.m. What to do: Take your dose at 3 p.m. as soon as you remember, then resume again the next morning at 8:00 a.m.<\/b><\/p>\n<h3 id=\"if-it-s-been-more-than-12-hours-since-your-last-dose\">If it\u2019s been more than 12 hours since your last dose<\/h3>\n<p>Dr. Lewis says there\u2019s no hard cut-off time for taking a late dose versus waiting for your next upcoming dose, but most providers recommend their patients follow a 12-hour rule. In other words, if it\u2019s been more than 12 hours since your last dose, skip the missed dose entirely and resume your normal dosing schedule the next day.<\/p>\n<p><b>Example: You normally take lisinopril at 8:00 a.m., but you forget about it until 10 p.m. What to do: Skip that day\u2019s dose and return to your regular schedule the next morning at 8:00 a.m.<\/b><\/p>\n<h3 id=\"what-not-to-do\">What <i>not<\/i> to do<\/h3>\n<p>While there\u2019s some flexibility with the dosing schedule if you miss a dose, there\u2019s one thing you should never do: take a double dose to \u201cmake up\u201d for the missed one. This can increase the likelihood of <a href=\"https:\/\/www.singlecare.com\/blog\/lisinopril-side-effects\/\">side effects<\/a> like low blood pressure (hypotension), dizziness, feeling lightheaded, and fainting, says Dr. Lewis. Some <a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/lisinopril-oral-route\/description\/drg-20069129\">side effects<\/a>, such as angioedema (swelling of the face, tongue, arms, or legs), are not thought to be dose related.<\/p>\n<p>&nbsp;<\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th colspan=\"3\">\n<h3 id=\"what-to-do-if-you-miss-a-dose-of-lisinopril\" style=\"text-align: center;\">What to do if you miss a dose of lisinopril<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Time since your usual dose<\/b><\/td>\n<td><b>What to do<\/b><\/td>\n<td><b>Why<\/b><\/td>\n<\/tr>\n<tr>\n<td>Less than 12 hours<\/td>\n<td>Take your missed dose as soon as you remember, then continue taking it as prescribed the next day<\/td>\n<td>It\u2019s close enough to your normal dosing time to take lisinopril without increasing your risk of side effects when you take it on time again the next day<\/td>\n<\/tr>\n<tr>\n<td>More than 12 hours<\/td>\n<td>Skip your missed dose and take your next scheduled dose as usual the next day<\/td>\n<td>It\u2019s too close to your next daily dose of lisinopril; taking two doses this close together could cause side effects like low blood pressure, dizziness, and fainting<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"what-happens-if-you-miss-two-or-more-doses\">What happens if you miss two or more doses?<\/h2>\n<p>Blood pressure medication like lisinopril only works if you take it consistently, says <a href=\"https:\/\/manhattancardiology.com\/team\/dr-david-rhee\/\">Dr. Rhee<\/a>, so if you miss two or more doses, you start losing the blood pressure-lowering effects. You can get back on track, but may need to contact your healthcare provider first.<\/p>\n<p>If you take lisinopril for high blood pressure and have missed two or more doses, you should <a href=\"https:\/\/www.heart.org\/en\/health-topics\/high-blood-pressure\/understanding-blood-pressure-readings\/monitoring-your-blood-pressure-at-home\">check your blood pressure at home<\/a>, if possible. If your blood pressure is within your goal range and you aren\u2019t having any noticeable symptoms of hypertension (more on that below), Dr. Rhee says you don\u2019t need to contact your provider unless they\u2019ve told you otherwise. You can <a href=\"https:\/\/www.singlecare.com\/blog\/how-long-does-it-take-for-lisinopril-to-work\/\">resume<\/a> taking your medication while monitoring your blood pressure and symptoms at home.<\/p>\n<p>However, if your blood pressure reading is high, you\u2019re having symptoms of high blood pressure, or you have no way to check your blood pressure at home, you should reach out to your provider\u2019s office immediately for guidance.<\/p>\n<p>You should also get in touch with your provider ASAP if you take <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/019777s076lbl.pdf\">lisinopril for heart failure, have a history of hypertension- or cardiac-related emergencies<\/a>, or have recently had surgery or a heart attack. You are at higher risk for complications from missed doses, and should contact your healthcare provider as soon as you realize you\u2019ve missed multiple doses.<\/p>\n<h2 id=\"can-missing-a-dose-be-dangerous-signs-to-watch-for\">Can missing a dose be dangerous? Signs to watch for<\/h2>\n<p>For most people, missing one dose of lisinopril is not dangerous. However, people with severe hypertension or who have recently had a heart attack are at higher risk for complications from missed doses, says Dr. Lewis. In those cases, you should check your blood pressure at home or contact your provider even if you\u2019ve only missed one dose.<\/p>\n<p>While missing a dose probably won\u2019t cause any side effects, there are a few <a href=\"https:\/\/www.heart.org\/en\/health-topics\/high-blood-pressure\/understanding-blood-pressure-readings\">warning signs<\/a> to watch for just in case, including:<\/p>\n<ul>\n<li>Chest pain<\/li>\n<li>Difficulty breathing<\/li>\n<li>Vision or speech changes<\/li>\n<li>Back pain<\/li>\n<li>Weakness or numbness in arms or legs<\/li>\n<li>Sudden, severe headache<\/li>\n<\/ul>\n<p>These are signs of a medical emergency; if you experience them after missing a dose of lisinopril, you should seek emergency medical care.<\/p>\n<p>Dr. Rhee also stresses that you should contact your provider ASAP if you have a blood pressure reading of 180\/120 mmHg or higher, even if you don\u2019t have symptoms. A reading in this range is a sign of <a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/24470-hypertensive-crisis\">severe hypertension, which can quickly turn into a hypertensive emergency<\/a> if your blood pressure doesn\u2019t come down or you begin to have any of the warning signs listed above.<\/p>\n<h2 id=\"what-if-you-miss-a-dose-of-lisinopril-hctz\">What if you miss a dose of lisinopril HCTZ?<\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril-hydrochlorothiazide?q=Lisinopril-Hydrochlorothiazide%20(Zestoretic)&amp;isHomeSearch=false\">Lisinopril-HCTZ<\/a> is a combination medication containing lisinopril and the diuretic hydrochlorothiazide (HCTZ). It\u2019s usually prescribed when lisinopril alone doesn\u2019t <a href=\"https:\/\/www.singlecare.com\/blog\/how-much-does-lisinopril-lower-blood-pressure\/\">lower your blood pressure<\/a> to your goal, says Dr. Lewis, because the diuretic component helps the kidneys excrete additional sodium and water, reducing overall blood volume.<\/p>\n<p>The rules for missed doses of lisinopril-HCTZ are the same as lisinopril:<\/p>\n<ul>\n<li>Take the missed dose as soon as you remember it, as long as it\u2019s within the 12-hour window of your normal dosage time<\/li>\n<li>Skip it and resume your normal schedule with your next dose if it\u2019s been more than 12 hours since you missed your dose<\/li>\n<li>Avoid extra doses of lisinopril-HCTZ if you miss a dose; never take two pills at the same time<\/li>\n<\/ul>\n<p>If you aren\u2019t sure what to do after missing a dose of lisinopril-HCTZ, contact your pharmacist or healthcare provider and let them know how many doses you missed or how long it\u2019s been since your last dose. They can counsel you on the best way to catch up.<\/p>\n<h2 id=\"how-to-avoid-missing-doses\">How to avoid missing doses<\/h2>\n<p>It\u2019s not uncommon to simply forget to take a dose of medication when you\u2019re busy or distracted, but if you\u2019re regularly forgetting your daily lisinopril, it\u2019s worth considering some <a href=\"https:\/\/www.singlecare.com\/blog\/medication-management-for-seniors\/\">strategies that can help you remember<\/a>.<\/p>\n<ul>\n<li>Take your medication at the same time every day so it naturally becomes a habit<\/li>\n<li>Set a daily alarm on your smartphone or tablet to remind you to take it<\/li>\n<li>Store your medication out where you can see it when you do other daily tasks (like making your morning coffee or brushing your teeth)<\/li>\n<li>Use a pill organizer so you have visual evidence of whether you\u2019ve already taken your medication or still need to take it<\/li>\n<li>Leave reminders for yourself on sticky notes, calendars, or planners<\/li>\n<\/ul>\n<p>If you know medication adherence is a challenge for you, don\u2019t be afraid to share that with your provider. They can help.<\/p>\n<p>Finding a reminder system that fits your routine can make it easier to take lisinopril consistently and help keep your blood pressure under control. \u201cI advise patients to be honest with their providers about their ability to take [lisinopril] as prescribed,\u201d says Dr. Rhee. \u201cWe understand the reality and difficulty of taking daily medications, [but] we need the full picture so we can understand the context behind the blood pressure number we see in our clinic rather than piling on more pills.\u201d<\/p>\n<h2 id=\"expert-takeaway\">Expert takeaway<\/h2>\n<ul>\n<li>\u201cI often prescribe lisinopril instead of other ACE inhibitors because of its relatively long half-life,\u201d explains Chad Shaffer, MD, member of the SingleCare Medical Board. \u201cThis characteristic means that it takes longer for a dose to be fully eliminated from the body and makes it more forgiving if the next dose is missed.\u201d<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Many people with high blood pressure, diabetes, or kidney disease take medications like lisinopril to manage their condition. It helps lower their risk of heart disease and kidney damage, so taking it once a day is important. But what happens if you miss a dose? Though you should always try to take lisinopril as prescribed, [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":637122,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,737,20951,8905],"coauthors":[8860],"class_list":["post-637121","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-heart-health","tag-high-blood-pressure","tag-seasonal","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Missed a dose of lisinopril? Here&#039;s what to do<\/title>\n<meta name=\"description\" content=\"Missing one dose of lisinopril usually isn&#039;t dangerous, but here&#039;s exactly what to do, when to call your provider, and what happens if you skip more than one.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/missed-dose-lisinopril\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Missed a lisinopriI dose?\" \/>\n<meta property=\"og:description\" content=\"What to do if you forgot your BP med\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/missed-dose-lisinopril\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2026-08-17T13:00:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2026\/08\/Blog_072826_What-happens-if-you-miss-a-dose-of-lisinopril-copy.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"Sarah Bradley\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Missed a lisinopriI dose?\" \/>\n<meta name=\"twitter:description\" content=\"What to do if you forgot your BP med\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sarah Bradley\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/missed-dose-lisinopril\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/missed-dose-lisinopril\\\/\"},\"author\":{\"name\":\"Heidi Borst\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/fda93df2f5d09af0d250b59dfb4b46f2\"},\"headline\":\"What happens if you miss a dose of lisinopril?\",\"datePublished\":\"2026-08-17T13:00:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/missed-dose-lisinopril\\\/\"},\"wordCount\":1605,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/missed-dose-lisinopril\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/Blog_072826_What-happens-if-you-miss-a-dose-of-lisinopril-copy.webp\",\"keywords\":[\"Drug safety\",\"Heart health\",\"High blood pressure\",\"Seasonal\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/missed-dose-lisinopril\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/missed-dose-lisinopril\\\/\",\"name\":\"Missed a dose of lisinopril? 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