{"id":7672,"date":"2019-12-27T13:00:57","date_gmt":"2019-12-27T18:00:57","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=7672"},"modified":"2026-01-07T12:58:50","modified_gmt":"2026-01-07T17:58:50","slug":"is-tylenol-an-nsaid","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/is-tylenol-an-nsaid\/","title":{"rendered":"Is Tylenol an NSAID?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Over-the-counter (OTC) medication is often the first line of defense against headaches, joint discomfort, and other minor ailments. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tylenol\"><span style=\"font-weight: 400;\">Tylenol<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/acetaminophen\"><span style=\"font-weight: 400;\">acetaminophen<\/span><\/a><span style=\"font-weight: 400;\">) and nonsteroidal anti-inflammatory drugs (NSAIDs) are OTC medicines used to treat mild-to-moderate aches and pains.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">NSAIDs are not only designed to lessen or eliminate the feeling of pain, but they also reduce inflammation as well. Many individuals are unclear whether or not Tylenol, the brand name for acetaminophen, is an NSAID. Tylenol is an analgesic (pain reliever), but it does not have anti-inflammatory properties, so Tylenol is not an NSAID.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Learn more about the differences between Tylenol and NSAIDs, their side effects, and which medication is better for the different types of pain you may experience.\u00a0<\/span><\/p>\n<h2 id=\"what-are-the-differences-between-tylenol-and-nsaids\"><span style=\"font-weight: 400;\">What are the differences between Tylenol and NSAIDs?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Acetaminophen blocks the brain from sending signals of pain to affected areas of the body. It is also a fever reducer. In addition to being the active ingredient in Tylenol, acetaminophen is found in numerous brand-name products, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/vicks-nyquil-severe-cold-flu\"><span style=\"font-weight: 400;\">NyQuil Cold and Flu<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/vicks-dayquil-cough\"><span style=\"font-weight: 400;\">DayQuil<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/alka-seltzer\"><span style=\"font-weight: 400;\">Alka-Seltzer Plus<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/excedrin-migraine\"><span style=\"font-weight: 400;\">Excedrin<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">While Tylenol may be useful for mild-to-moderate pain relief associated with headaches, menstrual cramps, toothaches, and so forth, an NSAID, like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\">, may be more suitable if there is inflammation or swelling associated with the pain. Some arthritis pain, joint pain, muscle aches, back pain, and sprains may benefit from the anti-inflammatory properties of an NSAID.\u00a0<\/span><\/p>\n<h2 id=\"how-to-choose-the-right-over-the-counter-pain-reliever\"><span style=\"font-weight: 400;\">How to choose the right over-the-counter pain reliever<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When choosing an OTC pain reliever, it is helpful to know the generic name of the medicine and if it is an NSAID. There are several factors that will help you determine which pain reliever is the best choice for you. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Your doctor\u2019s medical advice or a self-assessment of your specific ailment<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Your age, weight, medical condition, kidney function, and liver function<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If you are taking other medications and whether they could cause a drug-drug interaction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The medication\u2019s possible side effects<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The chart below outlines the various brand-name OTC drugs, their generic names, whether or not they are NSAIDs, and their general dosage recommendations for adults. Many of these medications are available as alternative and extra-strength doses. Prescription drugs, like Tylenol #3, are available to manage severe and chronic pain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">RELATED: <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tylenol-with-codeine-hydrocodone-oxycodone\/\"><span style=\"font-weight: 400;\">What\u2019s the best painkiller?<\/span><\/a><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th colspan=\"4\">\n<h2 id=\"otc-pain-relievers\"><span style=\"font-weight: 400;\">OTC pain relievers<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Brand Name<\/b><\/td>\n<td><b>Generic Name<\/b><\/td>\n<td><b>NSAID?<\/b><\/td>\n<td><b>General Adult Dose Information<\/b><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/tylenol\"><span style=\"font-weight: 400;\">Tylenol<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Acetaminophen<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC dosage: 325 mg per tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Directions: 2 tablets every 4-6 hours<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maximum dose: 3,000 mg per day<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/tylenol\/dosage\"><span style=\"font-weight: 400;\">Tylenol dosage guide<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/advil\"><span style=\"font-weight: 400;\">Advil<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/motrin-ib\"><span style=\"font-weight: 400;\">Motrin<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Ibuprofen<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC dosage: 200 mg per tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Directions: Take 1 tablet every 4-6 hours<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maximum dose: 1,200 mg per day<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/advil\/dosage\"><span style=\"font-weight: 400;\">Advil dosage guide<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/aleve\"><span style=\"font-weight: 400;\">Aleve<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Naproxen<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC dosage: 220 mg per tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Directions: Take 1 tablet every 8-12 hours<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maximum dose: 440 mg in an 8-12 hour period or 660 mg per day<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/aleve\/dosage\"><span style=\"font-weight: 400;\">Aleve dosage guide<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/bufferin\"><span style=\"font-weight: 400;\">Bufferin<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Aspirin\/antacid buffer<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC dosage: 325 mg per tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Directions: Take 2 tablets every 4 hours<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maximum dose: 3,900 mg per day<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/bayer-aspirin\"><span style=\"font-weight: 400;\">Bayer aspirin<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">Aspirin<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC dosage: 325 mg per tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Directions: Take 1-2 tablets every 4 hours<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maximum dose: 3,900 mg per day<\/span><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/anacin\"><span style=\"font-weight: 400;\">Anacin<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Aspirin\/caffeine<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC dosage: 400 mg of aspirin and 32 mg of caffeine per tablet<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Directions: Take 2 tablets every 6 hours<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Maximum dose: 3,200-256 mg (8 tablets) per day<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">Most of the OTC drugs above should not be taken on an empty stomach. It\u2019s recommended that you drink a full glass of water with each dose. Furthermore, most of these OTC drugs warn against using any OTC pain medicine for more than 10 consecutive days. Be sure to read the medication guide as dosage instructions may vary.\u00a0<\/span><\/p>\n<h2 id=\"pros-and-cons-of-acetaminophen-versus-nsaids\"><span style=\"font-weight: 400;\">Pros and cons of acetaminophen versus NSAIDs<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">You should always weigh the health benefits and risks associated with each type of drug before taking it. Consider the other medications you\u2019re currently taking and the health conditions you\u2019ve been diagnosed with. The side effects and drug-drug interactions are important factors in determining which is better: acetaminophen or NSAIDs.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, if you are prone to stomach ulcers, your doctor or pharmacist may recommend <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ibuprofen-vs-tylenol\/\"><span style=\"font-weight: 400;\">acetaminophen instead of ibuprofen<\/span><\/a><span style=\"font-weight: 400;\">. If you are at risk of a heart attack, taking aspirin could be the right choice for you. However, if you\u2019re already taking a blood thinner, then taking aspirin could be dangerous. Another drug, Anacin, contains caffeine, which may or may not be helpful to one\u2019s condition.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Compare the pros and cons of these types of pain relievers below and ask a healthcare professional for advice if you\u2019re unsure which one is best for you.<\/span><\/p>\n<h3 id=\"advantages-of-acetaminophen\"><span style=\"font-weight: 400;\">Advantages of acetaminophen<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Acetaminophen is less likely than an NSAID to cause <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2833976\/\"><span style=\"font-weight: 400;\">stomach upset<\/span><\/a><span style=\"font-weight: 400;\">. Individuals with sensitive stomachs, stomach ulcers, or acid reflux may benefit from taking acetaminophen instead of an NSAID.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Additionally, acetaminophen does not cause antiplatelet effects, so it could be a safer option than aspirin for people with bleeding disorders or those already taking blood thinners or antiplatelet medications.<\/span><\/p>\n<h3 id=\"side-effects-of-acetaminophen\"><span style=\"font-weight: 400;\">Side effects of acetaminophen<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some individuals reported side effects of acetaminophen. These include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sweating more than usual<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bruising<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Faint or lightheadedness\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble urinating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dark stool<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Jaundice (yellowing of skin and eyes)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ask your healthcare provider if you can take acetaminophen when pregnant or breastfeeding because some of the drug may be passed to the baby.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You should not take Tylenol if you have liver disease or cirrhosis of the liver because acetaminophen can further damage your liver and affect your ability to urinate properly. Additionally, combining alcohol with acetaminophen can cause liver damage or failure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Too much acetaminophen can cause Tylenol poisoning. Some side effects include vomiting, loss of appetite, extreme fatigue, and stomach pain. In severe cases, it can cause liver failure and death. Be careful when <\/span><a href=\"https:\/\/www.acsh.org\/news\/2018\/08\/28\/which-otc-painkillers-can-you-take-together-13353\"><span style=\"font-weight: 400;\">mixing medicine<\/span><\/a><span style=\"font-weight: 400;\"> that contains acetaminophen, such as Tylenol, DayQuil, NyQuil, Alka-Seltzer, and Excedrin.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Allergic reactions to acetaminophen can occur. If you have difficulty breathing or develop hives or blisters, stop taking the medication and seek medical attention right away.<\/span><\/p>\n<h3 id=\"advantages-of-nsaids\"><span style=\"font-weight: 400;\">Advantages of NSAIDs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A nonsteroidal anti-inflammatory drug has the added benefit of reducing inflammation. If you have swelling, an NSAID may be more appropriate to treat your ailment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">NSAIDs can also be safer, less addictive alternatives to prescription-strength painkillers, like OxyContin, Percocet, and Vicodin. Your healthcare provider may recommend NSAIDs for recovery after a minor injury or during physical therapy. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen\"><span style=\"font-weight: 400;\">Naproxen<\/span><\/a><span style=\"font-weight: 400;\"> was even ranked as the most effective treatment for knee osteoarthritis for improving both pain and function by the <\/span><a href=\"https:\/\/www.sciencedaily.com\/releases\/2018\/05\/180502094704.htm\"><span style=\"font-weight: 400;\">American Academy of Orthopaedic Surgeons<\/span><\/a><span style=\"font-weight: 400;\">. And, depending on your health condition, a doctor may recommend low-dose aspirin therapy to prevent blood clots and decrease your risk of a heart attack and stroke.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, long-term use of NSAIDs are not often recommended because they can cause serious side effects, which you can learn more about below.<\/span><\/p>\n<h3 id=\"side-effects-of-nsaids\"><span style=\"font-weight: 400;\">Side effects of NSAIDs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drugs can cause side effects, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lightheadedness and dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gas and bloating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea or constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain and heartburn<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Stomach pain and heartburn associated with NSAIDs like ibuprofen tend to be more severe than when using Tylenol. Ulcers may even occur. An increased risk for gastrointestinal bleeding is also a potential side effect of NSAIDs, especially when using aspirin.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Those with kidney disease or liver disease should avoid using NSAIDs. Additionally, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/over-the-counter-painkillers-with-alcohol\/\"><span style=\"font-weight: 400;\">combining alcohol with NSAIDs<\/span><\/a><span style=\"font-weight: 400;\"> can increase your risk of gastrointestinal bleeding.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">NSAIDs may also raise one\u2019s blood pressure. Talk to your doctor before taking OTC NSAIDs if you have high blood pressure or if you are at risk for or have had a heart attack or stroke. Aspirin is the only NSAID that lowers the risk of heart attack, stroke, and blood clots.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">NSAIDs may cause <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0890623824000285\"><span style=\"font-weight: 400;\">adverse effects during pregnancy<\/span><\/a><span style=\"font-weight: 400;\">, such as an increased risk of birth defects. There are many risks involved when <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/taking-medicine-while-pregnant\/\"><span style=\"font-weight: 400;\">taking medicine during pregnancy<\/span><\/a><span style=\"font-weight: 400;\">, so be sure to consult your healthcare provider before taking pain medicine while pregnant.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You may be experiencing an allergic reaction to an NSAID if you have difficulty breathing, wheezing, tightness of the chest, or a skin rash. Immediately stop taking the drug and seek professional medical assistance if this occurs.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Over-the-counter (OTC) medication is often the first line of defense against headaches, joint discomfort, and other minor ailments. Tylenol (acetaminophen) and nonsteroidal anti-inflammatory drugs (NSAIDs) are OTC medicines used to treat mild-to-moderate aches and pains.\u00a0 NSAIDs are not only designed to lessen or eliminate the feeling of pain, but they also reduce inflammation as well. [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":634950,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10708,808],"coauthors":[8861],"class_list":["post-7672","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-over-the-counter-medications","tag-pain-management","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Understand Tylenol vs. NSAIDs before treating pain or fever<\/title>\n<meta name=\"description\" content=\"Tylenol is not an NSAID. 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