{"id":8279,"date":"2020-01-21T10:00:44","date_gmt":"2020-01-21T15:00:44","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=8279"},"modified":"2023-08-05T13:04:28","modified_gmt":"2023-08-05T17:04:28","slug":"smoking-cessation-drugs","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/smoking-cessation-drugs\/","title":{"rendered":"What are my options for OTC and prescription smoking cessation drugs"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">It\u2019s never too late to quit smoking. Your risk for disease and early death is greatly reduced when you stop. There are health benefits at any age\u2014and the sooner you stop, the greater they are.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are many different effective smoking cessation drugs to help you kick the habit. It\u2019s important to find the stop-smoking aid that works best for you and that will help you give up cigarettes for good.<\/span><\/p>\n<h2><b>Why is it so hard to quit smoking?<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Nicotine is the primary substance in tobacco products that causes addiction. When you try to quit smoking, you may have symptoms of nicotine withdrawal because your body is dependent on the effects of nicotine. Common symptoms of nicotine withdrawal include irritability, anxiety, trouble sleeping, and increased appetite. The discomfort they cause can make you want to pick up the habit again, just to be rid of them.\u00a0<\/span><\/p>\n<h2><b>7 stop-smoking aids that work<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Fortunately, there are different options that help you gradually wean off of nicotine and reduce the withdrawal symptoms that make it so hard to quit.\u00a0<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nicotine gum<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nicotine lozenges<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nicotine patch<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nicotine inhaler<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nicotine nasal spray<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Non-nicotine tablets (Chantix, Zyban)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Off-label medications<\/span><\/li>\n<\/ol>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/wellbutrin-vs-chantix\/\"><b>Wellbutrin vs. Chantix<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">Pharmacotherapy for smoking cessation falls into two main categories: nicotine replacement therapy and non-nicotine smoking cessation products.<\/span><\/p>\n<h3><b>Nicotine replacement therapy (NRT)<\/b><\/h3>\n<p><a href=\"https:\/\/smokefree.gov\/tools-tips\/how-to-quit\/using-nicotine-replacement-therapy\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Nicotine replacement products<\/span><\/a><span style=\"font-weight: 400;\"> provide consistent levels of nicotine that gradually decrease over time.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">NRTs are available in different formulations and strengths: over-the-counter (OTC) and prescription. They are indicated by the U.S. Food and Drug Administration to be used for eight to 12 weeks but can be used longer if you and your healthcare provider feel that it is necessary.\u00a0<\/span><\/p>\n<h4><b>OTC NRTs<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">The OTC products are all available from various name brands and as generics. They include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Gum<\/b><span style=\"font-weight: 400;\"> is slowly chewed until it tingles. Then place the gum between the cheek and gum until the tingle is gone. Repeat this process until most of the tingle is gone (approximately 30 minutes). <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nicorette\"><span style=\"font-weight: 400;\">Nicorette<\/span><\/a><span style=\"font-weight: 400;\"> is a common brand name.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Lozenge<\/b><span style=\"font-weight: 400;\"> should be allowed to dissolve slowly (approximately 20-30 minutes) and should not be chewed or swallowed. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nicorette-mini\"><span style=\"font-weight: 400;\">Nicorette<\/span><\/a><span style=\"font-weight: 400;\"> is a common brand name.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Patch<\/b><span style=\"font-weight: 400;\"> is applied to a clean, dry area of your skin on the upper body or upper outer arm. Patches may be worn for 16-24 hours, and every patch should be applied to a different site to avoid skin irritation. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nicoderm-cq\"><span style=\"font-weight: 400;\">Nicoderm Cq<\/span><\/a><span style=\"font-weight: 400;\"> is a common brand name.<\/span><\/li>\n<\/ul>\n<h4><b>Prescription NRTs<\/b><\/h4>\n<p><span style=\"font-weight: 400;\">The prescription formulations of NRT are only available under the brand name Nicotrol and are available as:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Inhaler<\/b><span style=\"font-weight: 400;\"> formulation is breathed in by mouth multiple times a day. It may cause irritation of the mouth or throat when first using the inhaler. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nicotrol\"><span style=\"font-weight: 400;\">Nicotrol<\/span><\/a><span style=\"font-weight: 400;\"> is a common brand name.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nasal spray<\/b><span style=\"font-weight: 400;\"> is sprayed in the nose multiple times a day. It may cause irritation in the nose or throat when you begin using it.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Before beginning any NRT product, you should always consult your healthcare provider, especially:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Women who are pregnant or breastfeeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">People with diabetes, asthma, or a heart condition<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">People with high blood pressure or irregular heartbeat<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">You should stop taking an NRT product and call your healthcare provider if you have any of the following symptoms: nausea, dizziness, vomiting, or irregular heartbeat.<\/span><\/p>\n<h3><b>Non-nicotine smoking cessation products<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">If you can\u2019t use an NRT product because of a health condition, or you know you won\u2019t remember to use it multiple times a day, there are two prescription smoking cessation drugs available in tablet form:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/varenicline-tartrate\"><span style=\"font-weight: 400;\">Varenicline tartrate<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Zyban<\/b><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl\"><span style=\"font-weight: 400;\">bupropion hydrochloride<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Both of these stop-smoking aids affect chemicals in your brain to help reduce your nicotine cravings and are taken twice a day. The duration of therapy for these medications is generally 12 weeks, but if you\u2019ve successfully quit smoking, it can be used longer to reduce the risk of smoking relapse.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">*Varenicline tartrate was sold by its brand name Chantix, but <\/span><a href=\"https:\/\/www.news-medical.net\/news\/20230207\/In-the-wake-of-Chantixs-recall-Varenicline-use-for-nicotine-dependence-dropped-by-7525.aspx\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">in July 2021<\/span><\/a><span style=\"font-weight: 400;\">, Pfizer paused production and recalled the drug due to increased nitrosamine levels. The FDA later approved the generic version, which is what is widely available now.<\/span><\/p>\n<h3><b>Off-label medications to quit smoking<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">For smokers who are not successful with one of these treatments, some physicians will prescribe other medications <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> to help. Off-label just means the FDA does not approve them for this particular use. According to the <\/span><a href=\"https:\/\/www.cancer.org\/healthy\/stay-away-from-tobacco\/guide-quitting-smoking\/prescription-drugs-to-help-you-quit-smoking.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">American Cancer Society<\/span><\/a><span style=\"font-weight: 400;\">, these options include nortriptyline (antidepressant), clonidine (antihypertensive), cytisine (plant compound), and naltrexone (opiate antagonist).<\/span><\/p>\n<h2><b>Side effects of smoking cessation drugs<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">The FDA has issued some cautions for taking these smoking cessation medications but has determined that the benefits of quitting smoking outweigh the risk of taking these medications. You may experience adverse effects to your mental health. If you notice any changes in mood or behavior while taking these medications, report them to your healthcare provider and stop taking the medication.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some common side effects of varenicline tartrate include nausea, sleep problems, constipation, gas, and vomiting.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For Zyban, common side effects include dry mouth, insomnia, dizziness, constipation, and nausea.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you are considering medication to stop smoking, speak with your healthcare provider or pharmacist.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/wellbutrin-to-quit-smoking\/\"><b>Should you take Wellbutrin to stop smoking?<\/b><\/a><\/p>\n<h2><b>Compare smoking cessation drugs<\/b><\/h2>\n<p>&nbsp;<\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Form<\/b><\/td>\n<td><b>Rx \/ OTC<\/b><\/td>\n<td><b>Side effects<\/b><\/td>\n<td><b>SingleCare coupon<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nicorette<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nicotine gum<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Mood swings, drowsiness, difficulty concentrating, increased appetite, aches and pains, constipation<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nicorette\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Varenicline tartrate\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Non-nicotine tablet<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Rx<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nausea, sleep problems, constipation, gas, vomiting<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/varenicline-tartrate\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nicorette<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nicotine lozenge<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Mood changes, fatigue, trouble concentrating, weight gain, aches or pains, constipation<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nicorette\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nicotrol NS<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nicotine nasal spray<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Rx<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nose or throat irritation<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nicotrol-ns\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nicotrol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nicotine inhaler<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Rx<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Mouth or throat irritation<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nicotrol\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nicoderm Cq<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nicotine patch<\/span><\/td>\n<td><span style=\"font-weight: 400;\">OTC<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Application site irritation, dizziness, headache, stomach upset<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nicoderm-cq\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zyban<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Non-nicotine tablet<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Rx<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Dry mouth, insomnia, dizziness, constipation, nausea<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl-er-smoking-det\"><span style=\"font-weight: 400;\">Get coupon<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/wellbutrin-vs-chantix\/\"><b>Wellbutrin vs. Chantix<\/b><\/a><\/p>\n<h2><b>Frequently asked questions<\/b><\/h2>\n<h3><b>What does smoking cessation mean?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Smoking cessation is a process of quitting the use of tobacco. Tobacco contains a chemical called nicotine. Nicotine is addictive and causes withdrawal symptoms (cravings, nausea, irritability, mood swings, weight gain, etc.), making smoking cessation a difficult process.<\/span><\/p>\n<h3><b>What are smoking cessation products?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">There are two categories of smoking cessation products:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nicotine replacement therapy<\/b><span style=\"font-weight: 400;\">: Gum, lozenges, patches, nasal sprays, and inhalers that contain a lower dose of nicotine compared to smoking and reduce withdrawal symptoms.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Non-nicotine smoking cessation drugs<\/b><span style=\"font-weight: 400;\">: Oral prescription medications that do not contain nicotine but reduce withdrawal symptoms, such as cravings.<\/span><\/li>\n<\/ol>\n<h3><b>What is the most effective stop-smoking aid?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">There isn\u2019t a universally effective stop-smoking aid. A healthcare professional can help you find the best stop-smoking aid for you.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Nicotine replacement therapy methods are equally effective and increase smoking cessation rates by <\/span><a href=\"https:\/\/www.mdedge.com\/familymedicine\/article\/60156\/addiction-medicine\/what-most-effective-nicotine-replacement-therapy\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">150% to 200%<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2484340\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">One clinical trial<\/span><\/a><span style=\"font-weight: 400;\"> revealed no statistical significance between the products. However, another study found that <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/zyban-vs-chantix\/#efficacy\"><span style=\"font-weight: 400;\">Chantix was more effective than Zyban<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Note: E-cigarettes are not effective stop-smoking aids. Most studies show that e-cigarettes and other vaping devices do not significantly reduce cigarette use, according to <\/span><a href=\"https:\/\/drugfree.org\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Partnership to End Addiction<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3><b>What tablets can you take to stop smoking?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Chantix and Zyban are two types of tablets you can take to stop smoking. However, there are other off-label medications in capsule or tablet form that a healthcare provider may prescribe depending on your situation. These include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clonidine\"><span style=\"font-weight: 400;\">clonidine<\/span><\/a><span style=\"font-weight: 400;\"> (tablet), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/nortriptyline-hcl\"><span style=\"font-weight: 400;\">nortriptyline<\/span><\/a><span style=\"font-weight: 400;\"> (capsule), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naltrexone-hcl\"><span style=\"font-weight: 400;\">naltrexone<\/span><\/a><span style=\"font-weight: 400;\"> (tablet).<\/span><\/p>\n<h3><b>Is smoking cessation free?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">Smoking cessation could be free with insurance. Almost all health insurance plans (Marketplace, Medicaid, and Medicare Part D) cover smoking cessation therapies.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you don\u2019t have health insurance, you can still save on smoking cessation drugs with manufacturer coupons and prescription discount cards like SingleCare.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/free-chantix-without-insurance\/\"><b>How to get free Chantix (even without insurance)<\/b><\/a><\/p>\n<h3><b>How can I quit smoking without medication?<\/b><\/h3>\n<p><span style=\"font-weight: 400;\">You can successfully quit smoking without medication. Group therapy and quitting \u201ccold turkey\u201d are non-pharmacological approaches to smoking cessation. Those participating in group-based smoking cessation programs are <\/span><a href=\"https:\/\/www.cochrane.org\/CD001007\/TOBACCO_do-group-based-smoking-cessation-programmes-help-people-stop-smoking\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">50% to 130%<\/span><\/a><span style=\"font-weight: 400;\"> more likely to quit smoking. Additionally, quitting \u201ccold turkey\u201d and abstaining from nicotine altogether could be the <\/span><a href=\"https:\/\/newsroom.clevelandclinic.org\/2018\/11\/14\/study-cold-turkey-is-best-for-cutting-back-on-nicotine\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">healthiest approach<\/span><\/a><span style=\"font-weight: 400;\"> to quitting smoking. However, withdrawal symptoms from this method are likely to be more severe than a gradual program with nicotine replacement therapies.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>It\u2019s never too late to quit smoking. Your risk for disease and early death is greatly reduced when you stop. There are health benefits at any age\u2014and the sooner you stop, the greater they are.\u00a0 There are many different effective smoking cessation drugs to help you kick the habit. It\u2019s important to find the stop-smoking [&hellip;]<\/p>\n","protected":false},"author":97,"featured_media":8278,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8029],"tags":[10708,4325],"coauthors":[10842],"class_list":["post-8279","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-education","tag-over-the-counter-medications","tag-smoking","franchise-pharmacist-knows-best","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Smoking cessation drugs: What are my options?<\/title>\n<meta name=\"description\" content=\"There are many smoking cessation drugs\u2014prescription and OTC\u2014with and without nicotine. 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