
Eliquis, an anticoagulant medication used to treat and prevent blood clots and stroke, is covered by Medicare Part D. Though the exact costs vary by plan, the monthly copay averages between $44 and $50 per month, depending on the indication it is prescribed for.
Eliquis is also covered in inpatient settings under Medicare Part A and Part C if Eliquis is on the formulary, but not under Part B (outpatient services).
There are ways to save on Eliquis until a generic version becomes available in November 2026.
Eliquis (apixaban) is an anticoagulant (blood thinner) that’s part of a class of drugs called direct factor Xa inhibitors. It works by neutralizing the effects of enzymes that form blood clots, which in turn, helps reduce the chance of forming life-threatening blood clots and lowers the risk of stroke. Although it’s an effective blood thinner, it can be expensive, costing an average of $815 for 60, 5 mg tablets. Although Medicare Part D may cover Eliquis, the copay can be expensive. Fortunately, there are ways to reduce or eliminate the cost of this medication.
RELATED: Eliquis side effects
Eliquis is an expensive but effective direct oral anticoagulant (DOAC). According to Alain Tanbe, MD, a fellowship-trained, board-certified vascular surgeon at The Vascular Center at Mercy Medical Center, Eliquis treats and prevents several vascular conditions. Eliquis is used to:
Treat a deep vein thrombosis (DVT) or pulmonary embolism (PE)
Treat certain heart conditions like atrial fibrillation (AFib)
Prevent blood clots mainly after orthopedic procedures
Prevent or treat ischemic stroke
Eliquis may be prescribed as a long-term therapy or as a “bridge” therapy to help you recover from a recent surgery or procedure. Because it’s often taken twice daily, the cost may be high and burdensome for many patients, including those on Medicare.
Another reason for its high cost is that there is no generic alternative.
Medicare typically covers Eliquis, although coverage varies by plan and other factors.
Medicare has four different parts that cover different services:
Medicare Part A may cover Eliquis when administered in an inpatient setting, such as during a hospital stay.
Medicare Part B covers outpatient services and, therefore, does not cover Eliquis.
Medicare Part C will cover Eliquis if it is administered in an inpatient setting (see Part A above) or if the Part C plan includes prescription drug coverage and it is on the plan’s formulary (see Part D below).
Medicare Part D covers prescription medications that are taken at home. It is the most likely part of Medicare to cover your Eliquis prescription if it is included in your plan’s drug formulary.
In general, Medicare Part D plans, also known as the prescription drug benefit, cover Eliquis. You’ll be responsible for your monthly premiums and yearly deductible, as well as copays for your prescription medicines.
For 2025, the maximum deductible for Part D coverage is $590. This means that you’re responsible for up to your first $590 in prescription drug costs before coverage becomes available. Your annual deductible is based on your income and could change each year.
If you do not have Part D coverage, you can add it during Open Enrollment or during a Special Enrollment Period, but a late enrollment penalty may apply in some instances.
RELATED: How to avoid the Medicare Part D penalty?
The average retail price of a 30-day supply of Eliquis is typically $815 for 60, 5 mg tablets. However, those on Medicare can access a discounted rate through their Part D plan. How much you’ll pay for Eliquis with Medicare Part D depends on why it is prescribed. According to the manufacturer, patients with DVT/PE pay an average of $44 per month, and patients with AFib not caused by a heart valve problem pay an average of $54 per month. However, coverage varies by plan, and some may require prior authorization or step therapy.
Since Eliquis is expensive and a brand-name-only drug, your healthcare provider may have to submit the proper paperwork to your plan prior to your pharmacy dispensing it. This is known as a prior authorization, which requires your plan to “pre-approve” the medication before you can begin taking it. Once your plan approves Eliquis, you should be able to get your medication and pay your Medicare Part D copay.
Your plan may also require you to first try one or more other medications before seeking coverage for Eliquis. This is known as step therapy. Step therapy ensures that you’ve tried cheaper alternative medications before moving on to newer treatments.
The pharmacy will notify your healthcare provider if prior authorization or step therapy is required. You can also see if step therapy is required by reviewing your specific plan using the Medicare plan finder tool. Your healthcare provider will then submit the proper documents to request that your insurance company cover the medication. Prior authorization may take several days, so you may need to be patient before receiving coverage and starting treatment.
Eliquis assistance for Medicare patients exists in the form of the Medicare Extra Help program. Those who qualify for Medicare Extra Help may pay as little as $0 per month but no more than $12.15 per month for Eliquis. The Extra Help program is available to those on Medicare who have limited income and resources.
There are other ways you can save money on Eliquis. Some of these options, such as manufacturer copay cards and coupons, are short-term savings tools. But there are also some long-term strategies to consider. For example, you can talk to your healthcare provider about Eliquis alternatives that may be more affordable. Keep in mind that a generic version of Eliquis will be available in November 2026, which should be more affordable.
Your SingleCare prescription discount card can help you save up to 80% on medications like Eliquis and other anticoagulants. Anyone in the U.S. can use free Eliquis coupons at participating pharmacy locations nationwide, regardless of insurance or Medicare status, but they cannot be combined with insurance or Medicare. A 30-day supply of Eliquis costs about $488 with SingleCare.
Always seek medical advice from your healthcare provider before discontinuing Eliquis or switching to a new medication.
How much does Medicare drug coverage cost? Centers for Medicare and Medicaid Services
How much does Eliquis cost? Bristol Myers Squibb
Explore your Medicare coverage options, Centers for Medicare and Medicaid Services
Generic drugs: Questions & answers, Food and Drug Administration (2021)
Scott Dershowitz, LMSW, CMC, is a licensed social worker, geriatric care manager, and aging life care consultant based in New York City.
...Lindsay Modglin is a nurse with a clinical background in optometry and cardiology. She is now a freelance writer specializing in health and wellness topics for a variety of platforms. She aims to create educational content that provides value to her readers. When she’s not writing, you can find her enjoying the outdoors, traveling, or spending time with her husband and three children.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved