What is Amphadase? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Amphadase overview

BRAND NAMES:

  • Amphadase, Hylenex, Vitrase, Vitrase

Generic Names:

  • Amphadase

Uses:

  • Helps your body absorb other medicines. Also helps add fluid to your body when you are dehydrated.

Therapeutic Classes:

  • Tissue Permeability Modifier

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Amphadase used for?

What form(s) does Amphadase come in?

  • Injectable

What are common Amphadase dosages?

  • Vial 1ML of 150UNIT/ML

Amphadase images - What does Amphadase look like?

  • Amphadase
    1ml of 150unit/ml vial

How to take Amphadase

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Before your injection, you may be given a skin test to make sure you are not allergic to this medicine.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Before your injection, you may be given a skin test to make sure you are not allergic to this medicine.

What to do if you miss a dose of Amphadase

Amphadase contraindications - Who shouldn't take Amphadase?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronidase.

Amphadase warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns.

Amphadase interactions & what to avoid when taking Amphadase

  • Tell your doctor if you are pregnant or breastfeeding.

  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns.

Amphadase side effects - How does Amphadase make you feel?

Serious Side Effects

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Redness, swelling, itching, or pain at the injection site

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