Auvelity Coupons & Prices

Auvelity is used to treat major depressive disorder, or depression, in adults. This medicine was approved by the United States Food and Drug Administration (FDA) in 2022. It contains two active ingredients, dextromethorphan and bupropion. The average retail price of Auvelity is $1,563.56 per 60, 45-105mg tablet extended releases, but you can pay just $1,140.92 for 60, 45-105mg tablet extended releases of Auvelity with a SingleCare prescription drug discount card.

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Auvelity coupon at Walgreens Pharmacy
$1143.92
$ 1,141
$3 off with signupwith signup

Show this free card to your pharmacist.

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Auvelity coupon at Kroger Pharmacy
$1156.61
$ 1,154
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Auvelity coupon at Harris Teeter Pharmacy
$1156.61
$ 1,154
$3 off with signupwith signup
Auvelity coupon at Food Lion Pharmacy
$ 1,209
Auvelity coupon at CVS Pharmacy
$1217.18
$ 1,214
$3 off with signupwith signup
Auvelity coupon at Publix Pharmacy
$1237.33
$ 1,234
$3 off with signupwith signup
$1241.90
$ 1,239
$3 off with signupwith signup
$1241.90
$ 1,239
$3 off with signupwith signup
$1248.46
$ 1,245
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/18/2025

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About Auvelity

Auvelity is used to treat major depressive disorder, or depression, in adults. This medicine was approved by the United States Food and Drug Administration (FDA) in 2022. It contains two active ingredients, dextromethorphan and bupropion. The average retail price of Auvelity is $1,563.56 per 60, 45-105mg tablet extended releases, but you can pay just $1,140.92 for 60, 45-105mg tablet extended releases of Auvelity with a SingleCare prescription drug discount card.

Auvelity Price History & Information

Price History for Auvelity

60 count, tablet extended release, 45-105mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Auvelity

60 count, tablet extended release, 45-105mg
PharmacyAuvelity Retail PriceAuvelity SingleCare Price
CVS Pharmacy$1309.80$1219.80
Walmart$1413.00$1242.00
Walgreens$1411.40$1249.20
Kroger Pharmacy$1413.00$1156.80
Albertsons Pharmacy$1300.80$1238.40

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Auvelity

Auvelity is used to treat major depressive disorder, or depression, in adults. This medicine was approved by the United States Food and Drug Administration (FDA) in 2022. It contains two active ingredients, dextromethorphan and bupropion. The average retail price of Auvelity is $1,563.56 per 60, 45-105mg tablet extended releases, but you can pay just $1,140.92 for 60, 45-105mg tablet extended releases of Auvelity with a SingleCare prescription drug discount card.

Auvelity FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Auvelity cost without insurance?

The standard out-of-pocket cost of Auvelity without health insurance is $1,563.56 per 60, 45-105mg tablet extended releases though you can save using a SingleCare Auvelity coupon to pay only $1,140.92 for 60, 45-105mg tablet extended releases of Auvelity. If you don’t have access to an insurance plan, you can still use SingleCare for free Auvelity savings.

How much does Auvelity cost with insurance?

Each insurance formulary is different and may or may not cover Auvelity. The cost of Auvelity with insurance coverage varies depending on your plan - check with your insurance provider for specific drug coverage and copay details. If your insurance does not cover Auvelity, you can use SingleCare to get discounts on Auvelity at your participating pharmacy. Additionally, you can also use SingleCare coupons if you have Medicare or Medicaid. If Medicare or Medicaid don’t cover your Auvelity prescription, you can use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Auvelity with SingleCare versus your copay with insurance or Medicare. You can also check the manufacturer's website to find out about other savings options, such as the Auvelity Savings Card for eligible commercially insured patients. Check the website for more information about eligibility requirements and other program details. 

Does Medicare cover Auvelity, and how much does it cost?

Auvelity costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to find out whether your Medicare Part D or Medicare Advantage plan covers Auvelity and how much the copay or coinsurance is. If Auvelity is not covered by Medicare or if you have not met your plan’s deductible, you may have to pay the full price of $1,563.56 for 60, 45-105mg tablet extended releases. In that case, using a SingleCare coupon for Auvelity could save you more money than Medicare. Our lowest price for Auvelity is currently $1,140.92 for 60, 45-105mg tablet extended releases.

Is there a generic of Auvelity?

Auvelity is a brand name drug made by Axsome Therapeutics. There is not a generic version of Auvelity at this time. Use a SingleCare prescription drug discount card to pay $1,140.92 for 60, 45-105mg tablet extended releases.

What is Auvelity? 

Auvelity is used to treat depression in adults. Auvelity contains two active ingredients, dextromethorphan and bupropion. The exact way dextromethorphan works to treat depression is not fully understood. Bupropion, an antidepressant, may help by affecting brain chemicals like norepinephrine and dopamine.

Auvelity is an oral tablet that is taken by mouth with or without food. The tablet should be swallowed whole. You should not chew, crush, or split the tablet. Your healthcare provider will tell you how to take this medicine. Generally, it is prescribed to be taken once a day for 3 days, then twice a day after that. 

Try to limit or avoid alcohol while using Auvelity. If you drink heavily, consult your healthcare provider before stopping alcohol suddenly, as this could increase your risk of seizures. Also, avoid driving or operating heavy machinery until you see how Auvelity affects you, as it may impair your ability to do these safely.

Before taking Auvelity, tell your healthcare provider about any medical conditions you have, including if you are pregnant or breastfeeding. Auvelity is not recommended for use when pregnant or breastfeeding. 

Tell your provider about all the medications you take, including prescription and over-the-counter drugs, vitamins, and dietary supplements. Auvelity can interact with many medications, so your healthcare provider will need to check for drug interactions.

Auvelity is not safe for everyone. You should not use Auvelity if:

  • You are allergic to any ingredient in the medication

  • You are pregnant or breastfeeding

  • You have a history of seizure disorders

  • You have or have ever had bulimia or anorexia nervosa

  • You suddenly stop drinking alcohol

  • You suddenly stop taking benzodiazepines (anxiety medicines), barbiturates, or antiepileptic drugs

  • You are currently taking or have stopped taking an MAO inhibitor (MAOI) within the past 14 days

If you are getting a urine drug test, let the lab staff member know you take Auvelity. This is important because Auvelity may cause the test to show a positive result for amphetamines, and the lab can administer a more specific test to clarify the results.

What are the side effects of Auvelity?

The most common side effects of Auvelity include dizziness, headache, diarrhea, sleepiness, dry mouth, excess sweating, and sexual function problems. 

Auvelity has a black box warning, the most serious warning required by the FDA. The warning states that antidepressants may cause suicidal thoughts and behaviors, especially in children, adolescents, and young adults. People of any age who take an antidepressant such as Auvelity should be closely monitored for changes in mood and behavior, unusual thoughts, or suicidal thoughts and behaviors. 

Other serious side effects may occur, including, but are not limited to, seizures, high blood pressure, psychiatric and other mental health reactions, serotonin syndrome, a type of eye problem called angle-closure glaucoma, and dizziness (which can increase the risk of falls). Discuss these potentially serious side effects with your healthcare provider and find out what symptoms you should watch for.

Serious allergic reactions are rare. If you have symptoms of an allergic reaction, such as hives, trouble breathing, or swelling of the face, lips, tongue, or throat, get emergency medical help immediately. 

This is not a full list of side effects, and others may occur. Consult your doctor or pharmacist for more information about the side effects of Auvelity and what to do if you experience them. 

Does Auvelity cause weight loss?

In clinical studies, about 4% of people taking Auvelity reported a decrease in appetite. While weight loss is commonly associated with bupropion, one of the two active ingredients in Auvelity (also found in single-ingredient antidepressant medicines like Wellbutrin XL), clinical studies have not shown significant weight loss with Auvelity. In a 6-week study, people taking Auvelity lost an average of approximately half a pound.

How is Auvelity different than Wellbutrin? 

Wellbutrin is a medication that contains the active ingredient bupropion. It comes in several forms, including immediate-release and extended-release versions, and is commonly used to treat depression and prevent seasonal affective disorder.

Auvelity also contains bupropion, but it is a combination medication. In addition to bupropion, Auvelity includes another active ingredient called dextromethorphan. While both Wellbutrin and Auvelity use bupropion to work on brain chemicals, Auvelity also contains dextromethorphan, which works in a different way. Consult your healthcare professional for medical advice and more information about the best treatment for your condition. 

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Auvelity coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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