Clozapine Coupons & Prices

Clozapine FAQs

How much does Clozapine cost without insurance?

Patients can expect to pay a cash price of $61.18 or more for 30, 50mg tablets of Clozapine, depending on the dosage and quantity. Compare this price to a SingleCare Clozapine coupon: $23.98 for 30, 50mg tablets.

How much does Clozapine cost with insurance?

The retail price of your Clozapine copay depends on your insurance plan. Even with insurance, you should ask the case manager or pharmacist at the certified pharmacy to compare your copay cost to the Clozapine cost—currently $23.98 per 30, 50mg tablets—with a SingleCare Clozapine coupon.

Does Medicare cover Clozapine and how much does it cost?

Generic Clozapine is usually covered by Medicare Part D and Medicare Advantage prescription drug plans, but the brand-name version, Clozaril, usually is not. Consult with the certified pharmacy's pharmacist or case manager about your Medicare plan as well as using the SingleCare Clozapine coupon, which currently reduces the cost of Clozapine to $23.98 for 30, 50mg tablets.

What is the brand name of Clozapine?

Clozapine is a generic prescription drug manufactured by Sun, Teva, Mylan, and other generic manufacturers. The brand-name version of Clozapine is Clozaril.

What is Clozapine?

Clozapine is a generic prescription atypical antipsychotic drug that is primarily used to control the symptoms of schizophrenia, such as hallucinations (false perceptions) and delusions (false beliefs). Because Clozapine has serious and life-threatening side effects, Clozapine is prescribed only to patients with severe schizophrenia who have not responded to other therapies. Clozapine is also sometimes prescribed to reduce the suicide risk of patients with schizoaffective disorder who have a history of suicide attempts.

Clozapine is a tranquilizer that works by blocking chemicals in the brain responsible for sending signals between nerves. This slows and partly shuts down certain “circuits” in the brain. Many psychotic symptoms are due to hyperactivity in the brain, so slowing down the brain helps reduce these symptoms.

Because of its serious and sometimes life-threatening side effects, patients cannot fill a Clozapine prescription until they have been accepted in the Clozapine REMS (Risk Evaluation and Mitigation Strategy) program. The prescribing physician will help enroll the patient in the program and provide information about the program and its prescription procedures. Eligibility in the program will require monthly monitoring of absolute neutrophil count (a type of white blood cell).

Once enrolled, the patient or patient's caregiver will consult by phone with a case manager and a pharmacist from the pharmacy certified by the manufacturers. Necessary medical tests will also be sent to the pharmacist by the prescribing physician. Only after these consultations will the prescription be sent to the patient. Before taking Clozapine, tell your doctor about all of your medical conditions and history. Tell your doctor about all the medicines you take including Rx drugs, OTC medicines, and vitamins or supplements. This information will help your doctor determine if Clozapine is safe for you. 

Clozapine has a black box warning, which is the strongest warning required by the FDA. The warning states: 

• Clozapine can cause severe neutropenia (low neutrophils, which is a type of white blood cell), which is monitored by the absolute neutrophil count (ANC). Severe neutropenia can cause serious infection and death. Your doctor will monitor your ANC before and during treatment with Clozapine. 

• Clozapine is only available through the Risk Evaluation Mitigation Strategy (REMS) program.

• Clozapine can cause orthostatic hypotension, which is when your blood pressure drops when standing up from a sitting or lying position. Slow heart rate, fainting, and cardiac arrest can occur as well. Clozapine should be prescribed cautiously in people with heart or blood vessel problems.

• Clozapine may cause seizures. People who have a history of seizures should be prescribed Clozapine with caution. 

• Clozapine has caused heart problems which can be fatal. Symptoms such as chest pain, fast heart rate, palpitations, shortness of breath, low blood pressure, and EKG changes require emergency medical care.

• Clozapine is not approved for use in people with dementia-related psychosis.

What are the side effects of Clozapine?

Clozapine has severe and sometimes life-threatening side effects. Chief among these is that Clozapine severely lowers white blood cell counts, putting the patient at risk for infections. Clozapine can also cause seizures, heart disease, slow heartbeat, and heart attack.

The most common side effects of Clozapine are sedation, dizziness, headache, tremor, fast heart rate, low blood pressure, fainting, hypersalivation (increased saliva production), sweating, dry mouth, visual disturbances, nausea, constipation, and fever. More serious but less common side effects include liver problems, kidney problems, high blood sugar, low blood pressure, and severe muscle stiffness. Long-term continual use of Clozapine often leads to tardive dyskinesia, unusual permanent twitching and involuntary movements, which could persist for years following discontinuation of Clozapine.

Mental and mood changes include trouble thinking, loss of coordination, delirium (severe confusion), obsessive thinking, and strange dreams. Allergic reactions are rare, but discontinue Clozapine and get emergency medical help if there is any sign of an allergic reaction, such as hives, facial swelling, or difficulty breathing.

This is not a complete list of side effects that may occur. Consult with your physician about any concerns you may have with side effects.

Talk to your doctor or healthcare provider for additional medical advice regarding drug information and drug interactions.