What is Endari: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Endari overview

BRAND NAMES:

  • NutreStore, Endari, Enterex Glutapak-10

Generic Names:

  • Endari

Uses:

  • Treats short bowel syndrome and sickle cell disease. This medicine is an amino acid.

Therapeutic Classes:

  • Amino Acid Supplement, Gastrointestinal Agent

Forms:

  • Powder, Packet

How it’s taken:

  • By mouth

What is Endari used for?

What form(s) does Endari come in

  • Powder

  • Packet

What are common Endari doses?

  • Packet 1 Packet

  • Box 60 Packet

How to take Endari

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • For short bowel syndrome: Mix a packet of this medicine with water just before using it. Take it with a meal or snack every 2 to 3 hours while you are awake. Be sure to drink all of the mixture. Do not use this medicine during the night unless your doctor tells you to.

  • For sickle cell disease: Mix the oral powder with 4 to 6 ounces (oz) of food (including applesauce or yogurt) or with 8 oz of cold or room temperature beverage (including water, milk, or apple juice) as instructed by your doctor or pharmacist. Be sure to drink or swallow all of the mixture. Complete dissolution of the mixture is not required.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • For sickle cell disease: Mix the oral powder with 4 to 6 ounces (oz) of food (including applesauce or yogurt) or with 8 oz of cold or room temperature beverage (including water, milk, or apple juice) as instructed by your doctor or pharmacist. Be sure to drink or swallow all of the mixture. Complete dissolution of the mixture is not required.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • For short bowel syndrome: Mix a packet of this medicine with water just before using it. Take it with a meal or snack every 2 to 3 hours while you are awake. Be sure to drink all of the mixture. Do not use this medicine during the night unless your doctor tells you to.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

What to do if you miss a dose of Endari

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Endari contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to glutamine or glutamic acid.

Endari warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease or kidney disease.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Endari interactions

  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you have liver or kidney disease.

Endari side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fever, chills, cough, sore throat, body aches

  • Swelling in your face, hands, ankles, or feet

Less Serious Side Effects

  • Headache

  • Constipation, nausea, vomiting, passing gas, problems with your bowel movements, stomach pain

  • Joint, back, or chest pain

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