What is Icatibant? Uses, warnings & side effects

Updated May 14, 2025  •  Published May 29, 2021

Icatibant overview

BRAND NAMES:

  • Firazyr

Generic Names:

  • Icatibant Acetate

Uses:

  • Treats sudden attacks of hereditary angioedema (HAE).

Therapeutic Classes:

  • Immune Modulator

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Icatibant used for?

What form(s) does Icatibant come in?

  • Injectable

What are common Icatibant dosages?

  • Syringe 3ML of 30MG/3ML

Icatibant images - What does Icatibant look like?

  • Icatibant Acetate
    3ml of 30mg/3ml syringe

How to take Icatibant

  • Injection route: Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin. This medicine is usually injected in the abdomen or stomach.

  • Injection route: A nurse or other health provider will give you this medicine.

  • Injection route: You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection route: Use a new needle and syringe each time you inject your medicine.

  • Wash your hands with soap and water before and after using this medicine.

  • The liquid in the prefilled syringe should be clear and colorless. If the liquid is cloudy, discolored, or contains particles, do not use it. Choose another syringe.

  • Do not inject into an area that is bruised, painful, or swollen.

  • If your symptoms come back or do not get better, you may use another dose, but you must wait at least 6 hours after the first dose. Do not use this medicine more than 3 times in 24 hours.

  • Store this medicine in the refrigerator or at room temperature, in the original carton. Do not freeze.

  • Injection route: Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Injection route: Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

What to do if you miss a dose of Icatibant

Icatibant contraindications - Who shouldn't take Icatibant?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to icatibant.

Icatibant warnings

  • If your throat swells, go to the nearest hospital or emergency clinic after you use this medicine.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Tell your doctor if you are pregnant or breastfeeding

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Icatibant interactions & what to avoid when taking Icatibant

  • Some medicines and foods affect how icatibant works. Tell you doctor if you are also using an ACE inhibitor.

  • If your throat swells, go to the nearest hospital or emergency clinic after you use this medicine.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Icatibant side effects - How does Icatibant make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Redness, pain, itching, burning, bruising, warmth, or swelling where the shot is given