What is Minocycline ER: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jun 17, 2021

Minocycline ER overview

BRAND NAMES:

  • Solodyn, CoreMino, Ximino, Minolira

Generic Names:

  • Minocycline Hcl Er

Uses:

  • Treats acne. This medicine is a tetracycline antibiotic.

Therapeutic Classes:

  • Antibiotic, Antiacne Antibacterial

Forms:

  • Long Acting Tablet, Long Acting Capsule

How it’s taken:

  • By mouth

What is Minocycline ER used for?

What form(s) does Minocycline ER come in

  • Long Acting Tablet

  • Long Acting Capsule

What are common Minocycline ER doses?

  • Tablet 45mg

  • Tablet 55mg

  • Tablet 65mg

  • Tablet 80mg

  • Tablet 90mg

  • Tablet 105mg

  • Tablet 115mg

  • Tablet 135mg

  • Capsule 45mg

  • Capsule 90mg

  • Capsule 135mg

  • Tablet Extended Release 24 Hour 55MG

  • Tablet Extended Release 24 Hour 65MG

  • Tablet Extended Release 24 Hour 105MG

Common Minocycline ER prescriptions

  • Minocycline HCl ER
    105mg tablet

  • Minocycline HCl ER
    115mg tablet

  • Minocycline HCl ER
    135mg tablet

  • Minocycline HCl ER
    55mg tablet

  • Minocycline HCl ER
    65mg tablet

  • Minocycline HCl ER
    80mg tablet

  • Minocycline HCl ER
    90mg tablet

  • Minocycline HCl ER
    105mg tablet extended release 24 hour

  • Minocycline HCl ER
    80mg tablet extended release 24 hour

How to take Minocycline ER

  • Missed dose:Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • This medicine is not for long-term use.

  • Swallow the extended-release capsule or tablet whole. Do not crush, break, or chew it.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take this medicine with food if it irritates your throat or esophagus.

What to do if you miss a dose of Minocycline ER

Minocycline ER contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to minocycline or other tetracycline antibiotics, or if you are pregnant.

Minocycline ER warnings

  • Birth control pills may not work as well while you are using this medicine. Use an additional form of birth control with your pills.

  • This medicine may make you dizzy or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop taking this medicine.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • This medicine may cause the following problems:Severe diarrhea (may occur up to 2 months after you stop taking this medicine)Liver problemsBenign intracranial hypertension (increased pressure in the head)Autoimmune disorders, such as lupus-like syndromeDiscoloration of your skin, nails, eyes, teeth, or gums

  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, or vision problems.

  • This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Minocycline ER interactions

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop taking this medicine.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine may make you dizzy or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Birth control pills may not work as well while you are using this medicine. Use an additional form of birth control with your pills.

  • This medicine may cause the following problems:Severe diarrhea (may occur up to 2 months after you stop taking this medicine)Liver problemsBenign intracranial hypertension (increased pressure in the head)Autoimmune disorders, such as lupus-like syndromeDiscoloration of your skin, nails, eyes, teeth, or gums

  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, or vision problems.

  • Some foods and medicines can affect how minocycline works. Tell your doctor if you are using isotretinoin, a penicillin antibiotic, or a blood thinner (such as warfarin). Tell your doctor if you also take iron supplements or antacids that contain aluminum, calcium, or magnesium.

Minocycline ER side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Severe headache, dizziness, or vision changes

  • Diarrhea that may contain blood, stomach cramps

  • Swollen or tender lymph glands in your neck, armpit, or groin

  • Blistering, peeling, or red skin rash

  • Fever, joint pain, rash, or unusual weakness

Less Serious Side Effects

  • Discoloration of your skin, nails, teeth, or gums

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