Nplate (romiplostim) is an FDA-approved brand-name prescription drug that stimulates the bone marrow to make platelets, the blood cells responsible for blood clotting. Nplate is prescribed to people with immune thrombocytopenia (ITP), who have not responded to other treatments. ITP is a condition in which the body's immune system “misfires” and attacks blood platelets.
Nplate is generally administered as an in-office once-weekly subcutaneous injection performed by a healthcare professional. Nplate is not purchased in pharmacies. Continue to our FAQs section for more information about Nplate: how it works, possible side effects, how much Nplate costs, and how you can save money on your Nplate prescription. Nplate costs $3,492.09 at full retail price. A SingleCare Nplate coupon reduces that price to $2,694.45. Ask the clinic where you receive your Nplate injection if they will accept a SingleCare Nplate coupon; you could pay our lowest price of $2,694.45.
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Prices updated: 12/05/2025
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Nplate (romiplostim) is an FDA-approved brand-name prescription drug that stimulates the bone marrow to make platelets, the blood cells responsible for blood clotting. Nplate is prescribed to people with immune thrombocytopenia (ITP), who have not responded to other treatments. ITP is a condition in which the body's immune system “misfires” and attacks blood platelets.
Nplate is generally administered as an in-office once-weekly subcutaneous injection performed by a healthcare professional. Nplate is not purchased in pharmacies. Continue to our FAQs section for more information about Nplate: how it works, possible side effects, how much Nplate costs, and how you can save money on your Nplate prescription. Nplate costs $3,492.09 at full retail price. A SingleCare Nplate coupon reduces that price to $2,694.45. Ask the clinic where you receive your Nplate injection if they will accept a SingleCare Nplate coupon; you could pay our lowest price of $2,694.45.
Nplate (romiplostim) is an FDA-approved brand-name prescription drug that stimulates the bone marrow to make platelets, the blood cells responsible for blood clotting. Nplate is prescribed to people with immune thrombocytopenia (ITP), who have not responded to other treatments. ITP is a condition in which the body's immune system “misfires” and attacks blood platelets.
Nplate is generally administered as an in-office once-weekly subcutaneous injection performed by a healthcare professional. Nplate is not purchased in pharmacies. Continue to our FAQs section for more information about Nplate: how it works, possible side effects, how much Nplate costs, and how you can save money on your Nplate prescription. Nplate costs $3,492.09 at full retail price. A SingleCare Nplate coupon reduces that price to $2,694.45. Ask the clinic where you receive your Nplate injection if they will accept a SingleCare Nplate coupon; you could pay our lowest price of $2,694.45.
The pricing of Nplate is around $3,492.09 for uninsured customers. With a SingleCare Nplate coupon, you could pay a only $2,694.45 for 1, 250mcg solution reconstituted of Nplate if the clinic where you receive Nplate injections will accept a SingleCare savings card.
Your copay for Nplate with insurance will vary depending on your plan and the price charged for Nplate by the clinic where you get your injection. However, Nplate may be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic where you receive Nplate injections if they will accept a SingleCare Nplate drug coupon; you could pay only $2,694.45.
Nplate is usually not covered under Medicare Part D and Medicare Advantage prescription drug plans, but is covered under Medicare Part B as a medical benefit. Ask the clinic where you receive Nplate injections if they will accept a SingleCare savings card; you could pay only $2,694.45.
Nplate is a brand-name prescription drug that is not available as a generic.
Nplate is a brand-name prescription medication that stimulates the bone marrow to produce platelets. When a blood vessel gets damaged, platelets are the tiny cells that gather around the damage and initiate and glue together to form blood clots that repair the damage.
Nplate is prescribed to patients with immune thrombocytopenia (ITP), an autoimmune condition in which the immune system mistakenly attacks platelets. As platelet cell counts drop, people with ITP are at risk for excessive bleeding and bruising.
The active ingredient in Nplate, romiplostim, works by telling the bone marrow to make more platelets.
Nplate is administered as a once-weekly subcutaneous injection by a healthcare provider. Nplate is used in both children (1 year or older) and adults as a second-line treatment after other treatments have not succeeded. Nplate can also be used to increase survival in children (any age) and adults who have been exposed to radiation doses high enough to suppress the bone marrow.
The most common side effects of Nplate are muscle or joint pain, dizziness, insomnia, pain in the extremities, stomach pain, shoulder pain, indigestion, headache, and numbness/tingling.
Nplate increases the number of platelets in the blood, the cells responsible for blood clotting. As a result, the most serious side effects of Nplate are blood clot problems: stroke, blood clots in the lungs, and blood clots in the leg. Other serious side effects include ear infections, especially in children.
Allergic reactions are rare. Watch for allergic reactions to Nplate such as hives, wheezing, difficulty breathing, faintness, or sore throat. If you experience any of these effects, get emergency medical help.
This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist for additional information and medical advice about side effects before starting on Nplate.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved