What is Nuplazid: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Nuplazid overview

BRAND NAMES:

  • Nuplazid

Generic Names:

  • Nuplazid

Uses:

  • Treats hallucinations and delusions caused by Parkinson disease psychosis.

Therapeutic Classes:

  • Antipsychotic

Forms:

  • Capsule, Tablet

How it’s taken:

  • By mouth

What is Nuplazid used for?

What form(s) does Nuplazid come in

  • Capsule

  • Tablet

What are common Nuplazid doses?

  • Capsule 34MG

  • Tablet 10MG

Common Nuplazid prescriptions

  • Nuplazid
    34mg capsule

  • Nuplazid
    10mg tablet

  • Nuplazid
    17mg tablet

How to take Nuplazid

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Swallow the capsule or tablet whole. Do not crush, break, or chew it.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Swallow the capsule or tablet whole. Do not crush, break, or chew it.

What to do if you miss a dose of Nuplazid

Nuplazid contraindications

  • This medicine is not right for everyone. Do not take this medicine if you had an allergic reaction to pimavanserin.

Nuplazid warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or a history of heart rhythm problems.

  • This medicine may cause QT prolongation (abnormal heart rhythms).

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Nuplazid interactions

  • Some foods and medicines can affect how pimavanserin works. Tell your doctor if you are using any of the following:Carbamazepine, chlorpromazine, clarithromycin, gatifloxacin, indinavir, itraconazole, ketoconazole, moxifloxacin, phenytoin, rifampin, St John's wort, thioridazine, ziprasidoneMedicine to treat heart rhythm problems (including amiodarone, disopyramide, procainamide, quinidine, sotalol)

  • This medicine may cause QT prolongation (abnormal heart rhythms).

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Nuplazid side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fainting, dizziness, or lightheadedness

  • Fast, pounding, or uneven heartbeat

Less Serious Side Effects

  • Nausea

  • Abnormal dreams, confusion

  • Rapid weight gain, swelling in your hands, ankles, or feet

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