What is OsmoPrep: Uses, Warnings & Interactions

How to take OsmoPrep

• Follow the instructions on the medicine label if you are using this medicine without a prescription. If you are using the over-the-counter preparation for constipation, do not use more than 1 dose in 24 hours.

• Follow the schedule given to you by your doctor if you are using this medicine to empty your bowels before a surgery or medical test.

• Tablets: You will take several tablets at the same time. Your doctor will tell you how many tablets to take.Drink 8 ounces of clear liquids each time you take a group of tablets. Examples of clear liquids include water, flavored water, clear broth, herbal tea, black tea, coffee, clear soda, gelatin, popsicles, lemonade (no pulp), ginger ale, white grape juice, or apple juice.Do not eat or drink alcohol, milk, anything purple or red, or any foods that have pulp while you use this medicine.OsmoPrep®: Eat or drink only clear liquids after 12:00 PM (noon) on the day before and until after your colonoscopy. Do not eat solid food.

• Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Mix the oral liquid with at least 4 ounces of water before you drink it. After taking the liquid medicine, drink another full glass (8 ounces) of water.

• Drink as much extra liquid as you can before, during, and after taking this medicine. This will help replace the fluids you are losing with your bowel movements. This will also keep your kidneys working well.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The oral liquid can be chilled to improve the taste. Do not freeze the oral liquid.

• Follow the instructions on the medicine label if you are using this medicine without a prescription. If using the over-the-counter preparation for constipation, do not use more than 1 dose in 24 hours.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The oral liquid can be chilled to improve the taste. Do not freeze the oral liquid.

• Follow the instructions on the medicine label if you are using this medicine without a prescription. If you are using the over-the-counter preparation for constipation, do not use more than 1 dose in 24 hours.

• Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Mix the oral liquid with at least 4 ounces of water before you drink it. After taking the liquid medicine, drink another full glass (8 ounces) of water.

• Drink as much extra liquid as you can before, during, and after taking this medicine. This will help replace the fluids you are losing with your bowel movements. This will also keep your kidneys working well.

• Follow the instructions on the medicine label if you are using this medicine without a prescription. If using the over-the-counter preparation for constipation, do not use more than 1 dose in 24 hours.

• Follow the schedule given to you by your doctor if you are using this medicine to empty your bowels before a surgery or medical test.

• Tablets: You will take several tablets at the same time. Your doctor will tell you how many tablets to take.Drink 8 ounces of clear liquids each time you take a group of tablets. Examples of clear liquids include water, flavored water, clear broth, herbal tea, black tea, coffee, clear soda, gelatin, popsicles, lemonade (no pulp), ginger ale, white grape juice, or apple juice.Do not eat or drink alcohol, milk, anything purple or red, or any foods that have pulp while you use this medicine.OsmoPrep®: Eat or drink only clear liquids after 12:00 PM (noon) on the day before and until after your colonoscopy. Do not eat solid food.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

What to do if you miss a dose of OsmoPrep

OsmoPrep contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to sodium phosphate dibasic or sodium phosphate monobasic. Do not use it if you have stomach or bowel problems (including blockage, perforation, toxic colitis, toxic megacolon), if you had acute phosphate nephropathy, or if you have had stomach surgery (including gastric bypass or stapling surgery).

OsmoPrep warnings

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, heart failure, heart rhythm problems (including arrhythmia, QT prolongation), angina (chest pain), inflammatory bowel disease, ulcerative colitis, trouble with swallowing or gastric reflux, or a history of seizures or electrolyte imbalance. Tell your doctor if you had a recent heart attack or heart surgery. Tell your doctor if you are also on a low-salt diet.

• This medicine may cause the following:Kidney problemsHeart rhythm problemsSeizures.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Dizziness or fainting

• Dry mouth, increased thirst, muscle cramps, nausea or vomiting

• Fast, pounding, or uneven heartbeat

• Red or black stools

• Seizures

• Severe stomach pain, nausea, vomiting, or bloating

OsmoPrep interactions

• There are many other drugs that can interact with sodium phosphate. Tell your doctor about all other medicines you are taking, especially the following: Diuretic (water pill)Blood pressure medicine (including ACE inhibitors, ARBs)NSAID pain or arthritis medicine (including aspirin, ibuprofen, naproxen)Sodium phosphate-based laxative or enema to treat constipationTricyclic antidepressant (including amitriptyline, nortriptyline)

• Do not take any oral medicines within 1 hour before or after each dose of OsmoPrep®. Do not take OsmoPrep® if you have already used it in the last 7 days.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.