What is Rhofade: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Rhofade overview

BRAND NAMES:

  • Rhofade

Generic Names:

  • Rhofade

Uses:

  • Treats facial redness caused by rosacea.

Therapeutic Classes:

  • Dermatological Agent

Forms:

  • Cream

How it’s taken:

  • On the skin

What is Rhofade used for?

What form(s) does Rhofade come in

  • Cream

What are common Rhofade doses?

  • Tube 30GM of 1%

Common Rhofade prescriptions

  • Rhofade
    30gm of 1% tube

  • Rhofade
    30gm of 1% tube of cream

How to take Rhofade

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • To use: If you are using the pump for the first time, prime it by holding the pump upright and press down several times until the cream is dispensed onto a tissue. Pump three more times onto the tissue and throw away the tissue. Press down on the pump one time to dispense a pea-sized amount of the cream to your fingertip. Apply a thin layer of the cream to cover the entire face (forehead, nose, cheeks, chin). Do not apply the cream to irritated skin or open wounds.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • To use: If you are using the pump for the first time, prime it by holding the pump upright and press down several times until the cream is dispensed onto a tissue. Pump three more times onto the tissue and throw away the tissue. Press down on the pump one time to dispense a pea-sized amount of the cream to your fingertip. Apply a thin layer of the cream to cover the entire face (forehead, nose, cheeks, chin). Do not apply the cream to irritated skin or open wounds.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

What to do if you miss a dose of Rhofade

Rhofade contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to oxymetazoline.

Rhofade warnings

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel problems, high or low blood pressure, irritated skin or open sores on the face, narrow-angle glaucoma, Raynaud syndrome, Sjören syndrome, scleroderma, thromboangiitis obliterans, enlarged prostate, or a history of stroke.

  • This medicine may cause the following problems:Changes in blood pressureIncrease risk of angle closure glaucoma

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.

Rhofade interactions

  • Some medicines can affect how oxymetazoline works. Tell your doctor if you are using digoxin or blood pressure medicines.

  • Topical application routeDo not put cosmetics or skin care products on the treated skin.

Rhofade side effects

Serious Side Effects

  • Worsening of rosacea pimples

  • Blurred vision, eye pain

  • Chest pain, trouble breathing

  • Fast, slow, or pounding heartbeat

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing