What is Skin Prep Spray? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

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Skin Prep Spray overview

BRAND NAMES:

  • Adapt Paste, Coloplast Prep, D-R-C Peri-Rectal Creme, Elon Barrier Protectant, Handshield, Kerodex 51, Kerodex 71, Lantiseptic Skin Protectant, PeriShield, Prean, Skin-Prep, Skin-Prep Wipes, Soothe & Cool Inzo, Soothe & Cool Inzo, Soothe & Cool Inzo

Generic Names:

  • Skin Prep Spray

Uses:

  • Treats and prevents diaper rash, severely dry or chapped skin, minor burns, and other skin irritations.

Therapeutic Classes:

  • Dermatological Agent, Protectant, Dermatological

Forms:

  • Ointment, Cream, Lotion, Pad, Swab, Spray, Paste

How it’s taken:

  • On the skin

What is Skin Prep Spray used for?

What form(s) does Skin Prep Spray come in?

  • Ointment

  • Cream

  • Lotion

  • Pad

  • Swab

  • Spray

  • Paste

What are common Skin Prep Spray dosages?

  • Bottle 118ML of

How to take Skin Prep Spray

  • Change wet and soiled diapers right away. Clean the diaper area and allow to dry.

  • Clean minor wounds before applying this medicine.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Topical application routeApply a thin layer of the medicine to the affected area. Rub it in gently. Do not rub in the medicine that came in a pad, swab, or spray. Allow the pad, swab, or spray medicine to dry before covering the treated skin area.

  • Apply this medicine as often as needed (for babies, with each diaper change), unless your doctor tells you otherwise.

  • Change wet and soiled diapers right away. Clean the diaper area and allow to dry.

  • Topical application routeApply a thin layer of the medicine to the affected area. Rub it in gently. Do not rub in the medicine that came in a pad, swab, or spray. Allow the pad, swab, or spray medicine to dry before covering the treated skin area.

  • Clean minor wounds before applying this medicine.

  • Apply this medicine as often as needed (for babies, with each diaper change), unless your doctor tells you otherwise.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

What to do if you miss a dose of Skin Prep Spray

  • Store this medicine at room temperature in a closed container, away from heat, moisture, and direct light.

  • Keep this and all medicine out of the reach of children.

Skin Prep Spray contraindications - Who shouldn't take Skin Prep Spray?

  • You should not use this medicine if you have had an allergic reaction to petrolatum, lanolin, dimethicone, or zinc oxide.

Skin Prep Spray warnings

  • Do not use this medicine on deep cuts or wounds or on skin that is infected.

  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.

  • If someone accidentally swallows some of this medicine, call your local poison control center.

  • For adult women, make sure your doctor knows if you are pregnant or breast feeding.

  • If rash gets worse or does not get better within 7 days, call your doctor.

Skin Prep Spray interactions & what to avoid when taking Skin Prep Spray

  • For adult women, make sure your doctor knows if you are pregnant or breast feeding.

  • Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.

  • If someone accidentally swallows some of this medicine, call your local poison control center.

  • If rash gets worse or does not get better within 7 days, call your doctor.

  • Do not use this medicine on deep cuts or wounds or on skin that is infected.

Skin Prep Spray side effects - How does Skin Prep Spray make you feel?

Serious Side Effects

  • Increased redness or blistering on the skin

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