Systane Complete is an over-the-counter eye drop that helps to relieve the symptoms of dry eye. Systane Complete is manufactured by Alcon Laboratories. Propylene glycol is an active ingredient contained in Systane Complete. Currently, there is no generic version of Systane Complete. For 10, 0.6% solution (quantity in ml)s, the average cost of Systane Complete is $21.17. You can use our Systane Complete coupons on our website or app at participating pharmacies nationwide to pay as low as $12.97.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 05/06/2026
Systane Complete is an over-the-counter eye drop that helps to relieve the symptoms of dry eye. Systane Complete is manufactured by Alcon Laboratories. Propylene glycol is an active ingredient contained in Systane Complete. Currently, there is no generic version of Systane Complete. For 10, 0.6% solution (quantity in ml)s, the average cost of Systane Complete is $21.17. You can use our Systane Complete coupons on our website or app at participating pharmacies nationwide to pay as low as $12.97.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Systane Complete Retail Price | Systane Complete SingleCare Price |
|---|---|---|
| Walmart | $14.10 | $14.10 |
| Walgreens | $19.88 | $19.70 |
| Kroger Pharmacy | $12.60 | $12.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Systane Complete is an over-the-counter eye drop that helps to relieve the symptoms of dry eye. Systane Complete is manufactured by Alcon Laboratories. Propylene glycol is an active ingredient contained in Systane Complete. Currently, there is no generic version of Systane Complete. For 10, 0.6% solution (quantity in ml)s, the average cost of Systane Complete is $21.17. You can use our Systane Complete coupons on our website or app at participating pharmacies nationwide to pay as low as $12.97.
Purchasing Systane Complete without insurance would cost about $21.17 for 10, 0.6% solution (quantity in ml)s. When you use a SingleCard discount card you can save significantly on your Systane Complete price. With SingleCare as a savings method option, you could pay just $12.97 for your next prescription or refill of Systane Complete.
Normally, insurance companies will only provide coverage for prescription drugs. Since Systane Complete is an OTC medicine, you may not benefit from insurance coverage. However, you can discuss your options with your healthcare provider, as some dry eye treatments can be prescribed for certain conditions.
Your insurance plan and its coverage will determine your copay for Systane Complete, but this price might be even lower with a SingleCare savings card. Bring your SingleCare card, coupon, or app to a local drugstore to learn more about your savings options.
Medicare does not typically cover over-the-counter products, like Systane Complete. If you have a prescription for it, you can use SingleCare Systane Complete coupons at participating pharmacies such as CVS Pharmacy, Walmart, or Walgreens to claim significant savings on Systane Complete. Have your local pharmacist run your SingleCare discount card to start saving on Systane Complete and other prescription medications today.
Systane Complete is a brand-name eye drop used to relieve dry eye. There is no generic version of Systane Complete. However, there are other brand-name Systane products, including Systane Ultra Lubricant Eye Drops and Systane Balance Lubricant Eye Drops. Browse these products and ask a pharmacist which is best for your condition.
Systane Complete is taken by persons affected with various dry eye conditions, such as evaporative dry eye, aqueous tear deficient dry eye, or mixed dry eye, to produce artificial tears for lasting relief.
Evaporative dry eye is a common form of dry eye syndrome that causes a deficiency in quality tears produced by the eye. The lacrimal glands are responsible for the creation of tears. It's important for the eye to produce tears in order to prevent irritation. When the lacrimal glands produce little to no tears, patients can be diagnosed with aqueous tear deficient dry eye or with mixed eye.
Systane Complete provides the eyes with fast hydration and tear evaporation protection. Systane Complete lubricant eye drops can also be used to reduce irritation, dryness, burning, and discomfort in the eyes. Note: If you wear contact lenses, you would need to remove them before inserting Systane Complete into your eye.
Before using Systane Complete, you should talk with your healthcare provider to see if Systane Complete is right for you. You should always use Systane Complete as directed from the proper safety instructions written on the bottle or from your doctor's medical advice.
Before taking Systane Complete, you should inform your doctor about your medical history including information on medications you are currently using. Some medications that treat conditions such as depression, allergies, and blood pressure can increase your risk of having dry eye symptoms. Depending on your medical condition, your healthcare provider may ask you to temporarily stop using these medications to see if they are causing you to experience dry eye.
You may experience some minor side effects from this dry eye relief medication. Your vision may be blurred temporarily when using Systane Complete. You may also experience a slight burning or irritation temporarily when you insert Systane Complete into each eye. If you experience these side effects consistently or if they worsen, you should talk to a healthcare professional, as you may need to change your medication.
If you are pregnant or breastfeeding, you should share this information with your doctor to see if Systane Complete is right for you.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved