What is Trodelvy: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 31, 2020

Trodelvy overview

BRAND NAMES:

  • Trodelvy

Generic Names:

  • Trodelvy

Uses:

  • Treats breast cancer.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Trodelvy used for?

What form(s) does Trodelvy come in

  • Injectable

What are common Trodelvy doses?

  • Solution Reconstituted 180MG

Common Trodelvy prescriptions

  • Trodelvy
    180mg solution reconstituted

How to take Trodelvy

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to stay in place for at least 3 hours for the first dose, then 1 or 2 hours for the next doses.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to stay in place for at least 3 hours for the first dose, then 1 or 2 hours for the next doses.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

What to do if you miss a dose of Trodelvy

Trodelvy contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to sacituzumab govitecan-hziy, or if you are pregnant.

Trodelvy warnings

  • Do not breastfeed during treatment with this medicine and for at least 1 month after the last dose.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Tell your doctor if you have kidney disease, liver disease, any type of infection, or an enzyme problem called reduced UGT1A1 activity.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Talk with your doctor before receiving this medicine if you plan to have children. Some women who receive this medicine have become infertile (unable to have children).

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Use an effective form of birth control during treatment and for at least 6 months after the last dose. Male patients with female partners should use an effective form of birth control during treatment and for at least 3 months after the last dose.

  • This medicine often causes diarrhea. Diarrhea can begin while you are receiving a dose of medicine or shortly afterward, or it may occur more than 24 hours later. Your doctor may give you medicine to treat diarrhea. Follow instructions carefully.

Trodelvy interactions

Trodelvy side effects

Serious Side Effects

  • Severe diarrhea, nausea, and vomiting

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Unusual bleeding, bruising, or weakness

  • Fever, chills, cough, sore throat, body aches

Less Serious Side Effects

  • Constipation, stomach pain, loss of appetite

  • Tiredness

  • Hair loss

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Skin rash

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