What is Yondelis? Uses, warnings & side effects

How to take Yondelis

• Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

• Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

What to do if you miss a dose of Yondelis

Yondelis contraindications - Who shouldn't take Yondelis?

• This medicine is not right for everyone. You should not receive it if you had an allergic reaction to trabectedin, or if you are pregnant or breastfeeding.

Yondelis warnings

• Injection routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Use an effective form of birth control during treatment and for at least 2 months after your last dose. Men who are receiving this medicine should use effective birth control during treatment and for at least 5 months after your final dose.

• Tell your doctor if you have kidney disease, liver disease, or heart disease.

• This medicine may cause the following problems:Severely low white blood cells counts, which may lead to serious or life-threatening infectionRhabdomyolysis (severe muscle problem)Liver damageDamage to the heart muscle, heart failureDamage to the skin around the injection site

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

• Rapid weight gain, swelling in your hands, ankles, or feet, chest pain, trouble breathing, unusual tiredness

• Severe muscle pain, tenderness, or weakness

• Unusual bleeding, bruising, or weakness

Yondelis interactions & what to avoid when taking Yondelis

• Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

• This medicine may cause the following problems:Severely low white blood cells counts, which may lead to serious or life-threatening infectionRhabdomyolysis (severe muscle problem)Liver damageDamage to the heart muscle, heart failureDamage to the skin around the injection site

• Some foods and medicines can affect how trabectedin works. Tell your doctor if you are using boceprevir, clarithromycin, conivaptan, indinavir, itraconazole, ketoconazole, lopinavir, nefazodone, nelfinavir, phenobarbital, posaconazole, rifampin, ritonavir, saquinavir, St John's wort, telaprevir, telithromycin, or voriconazole.

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.