Can Adderall make you tired?

Medically reviewed by Anne Jacobson, MD, MPH
Board-Certified Family Physician
Written by Christine Bryant
Contributor
Updated Jan 22, 2026  •  Published Jan 22, 2026
Datos Verificados

Yes, Adderall can make some people tired, even though it is a stimulant. This can happen due to side effects, rebound fatigue as the medication wears off, poor sleep, skipped meals, underlying conditions, or drug interactions, which is why persistent fatigue should be discussed with a healthcare provider.

Expert perspective

  • Amir Miodovnik, MD

  • “Tiredness is a reported side effect of Adderall, occurring in 2% of children and 6% of adults - consistently higher than placebo in randomized controlled trials”

  • Expert bio: Amir Miodovnik is a developmental-behavioral pediatrician with Pediatric Developmental Solutions outside Washington, D.C.

  • Verification

Want to learn more about Adderall fatigue? Read our guide to Adderall-induced sleepiness

See more Adderall resources below:

Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your psychiatrist or other healthcare provider before making changes to your medication regimen.

Sources

  • Amir Miodovnik, MD, a developmental-behavioral pediatrician with Pediatric Developmental Solutions outside Washington, D.C.

Medically reviewed by Anne Jacobson, MD, MPH
Board-Certified Family Physician

Anne Jacobson, MD, MPH, is a board-certified family physician, writer, editor, teacher, and consultant. She is a graduate of University of Wisconsin School of Medicine and Public Health, and trained at West Suburban Family Medicine in Oak Park, Illinois. She later completed a fellowship in community medicine at PCC Community Wellness and a master's in Public Health at the University of Illinois-Chicago. She lives with her family near Chicago.

... 
Written by Christine Bryant
Contributor

Christine Bryant is a freelance health and business writer based in Florida. A graduate of Ohio University’s E.W. Scripps School of Journalism, she began her writing career as a newspaper reporter. Her work has been published in newspapers, magazines and online publications. She also works with non-profit organizations and businesses to develop content and enhance their communication strategies.

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