What is Amlodipine-Atorvastatin: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Amlodipine-Atorvastatin overview

BRAND NAMES:

  • Caduet, Caduet

Generic Names:

  • Amlodipine-Atorvastatin

Uses:

  • Treats and prevents angina (chest pain), stroke, heart attack, or other heart and blood vessel diseases. Also lowers high blood pressure and high cholesterol levels. This medicine contains a calcium channel blocker (CCB) and a statin.

Therapeutic Classes:

  • Calcium Channel Blocker/HMG-COA Reductase Inhibitor Combination

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Amlodipine-Atorvastatin used for?

Amlodipine-Atorvastatin is a combination drug that is used to treat patients with high blood pressure (hypertension). This medication may also be used to relieve chest pains (angina). Using Amlodipine-Atorvastatin can lower your risk of having a stroke, heart attack, and other conditions. This medication is indicated for use by adults and is available as a tablet.

What form(s) does Amlodipine-Atorvastatin come in

  • Tablet

What are common Amlodipine-Atorvastatin doses?

  • Tablet 10-10MG

  • Tablet 5-10MG

  • Tablet 5-20MG

  • Tablet 10-20MG

  • Tablet 10-40MG

  • Tablet 5-40MG

  • Tablet 10-80MG

  • Tablet 2.5-10MG

  • Tablet 5-80MG

  • Tablet 2.5-40MG

  • Tablet 2.5-20MG

  • Bottle 30 Tablets

Common Amlodipine-Atorvastatin prescriptions

  • amLODIPine-Atorvastatin
    30 tablets bottle

  • amLODIPine-Atorvastatin
    10-10mg tablet

  • amLODIPine-Atorvastatin
    10-20mg tablet

  • amLODIPine-Atorvastatin
    10-40mg tablet

  • amLODIPine-Atorvastatin
    10-80mg tablet

  • amLODIPine-Atorvastatin
    2.5-10mg tablet

  • amLODIPine-Atorvastatin
    2.5-20mg tablet

  • amLODIPine-Atorvastatin
    2.5-40mg tablet

  • amLODIPine-Atorvastatin
    5-10mg tablet

  • amLODIPine-Atorvastatin
    5-20mg tablet

  • amLODIPine-Atorvastatin
    5-40mg tablet

  • amLODIPine-Atorvastatin
    5-80mg tablet

How to take Amlodipine-Atorvastatin

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take this medicine at the same time each day.

  • Swallow the tablet whole. Do not break, crush, or chew it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: If you miss a dose and it is less than 12 hours until your next regular dose, skip the missed dose and take your next dose at the regular time. If you miss a dose and it is more than 12 hours until your next regular dose, take the missed dose as soon as possible, and then go back to your regular schedule.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take this medicine at the same time each day.

  • Missed dose: If you miss a dose and it is less than 12 hours until your next regular dose, skip the missed dose and take your next dose at the regular time. If you miss a dose and it is more than 12 hours until your next regular dose, take the missed dose as soon as possible, and then go back to your regular schedule.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Swallow the tablet whole. Do not break, crush, or chew it.

What to do if you miss a dose of Amlodipine-Atorvastatin

Amlodipine-Atorvastatin contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to amlodipine or atorvastatin, if you are pregnant or breastfeeding, or if you have active liver disease.

Amlodipine-Atorvastatin warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you have kidney disease, diabetes, heart or blood vessel disease, heart problems, low blood pressure, any type of infection, thyroid problems, electrolyte imbalance, seizures, or a history of stroke or heart attack. Tell your doctor if you are having surgery or if you drink more than 2 alcoholic drinks per day.

  • This medicine may cause the following problems:Severe muscle problems (including myopathy, immune-mediated necrotizing myopathy), especially when used with other medicinesRhabdomyolysis (severe muscle weakness) that could lead to kidney damageLiver problemsWorsening chest pain or heart attackChanges in blood sugar levelBrain or nerve problems, including bleeding or swelling in the brain, or hemorrhagic stroke

  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.

  • Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure high blood pressure, but it will help keep it in normal range. You may have to take blood pressure medicine for the rest of your life.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Unexplained fever, unusual tiredness

  • Rapid weight gain, swelling in your hands, ankles, or feet

Amlodipine-Atorvastatin interactions

  • This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you feel lightheaded or dizzy.

  • Do not stop taking this medicine without asking your doctor, even if you feel well. This medicine will not cure high blood pressure, but it will help keep it in a normal range. You may need to take blood pressure medicine for the rest of your life.

  • Tell your doctor if you usually have more than 2 drinks of alcohol per day.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Some foods and medicines can affect how amlodipine/atorvastatin works. Tell your doctor if you are using any of the following: Boceprevir, cimetidine, colchicine, cyclosporine, digoxin, diltiazem, elbasvir/grazoprevir, fenofibrate, gemfibrozil, glecaprevir/pibrentasvir, letermovir, niacin (vitamin B3), rifampin, sildenafil, spironolactone, tacrolimus, telaprevirBirth control pillsMedicine to treat an infection (including clarithromycin, erythromycin, itraconazole, ketoconazole)Medicine to treat HIV/AIDS (including darunavir/ritonavir, efavirenz, fosamprenavir, fosamprenavir/ritonavir, lopinavir/ritonavir or simeprevir, nelfinavir, ritonavir, saquinavir/ritonavir, tipranavir/ritonavir)

  • Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

  • This medicine may cause the following problems:Muscle damage, which can lead to kidney problemsLiver problemsWorsening of angina, increased risk of heart attack or stroke

Amlodipine-Atorvastatin side effects

Serious Side Effects

  • Fast, pounding, or uneven heartbeat

  • Change in how much or how often you urinate, painful urination

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Numbness or weakness in your arm or leg, or on one side of your body

  • Chest pain that may spread, trouble breathing, unusual sweating

  • Lightheadedness, dizziness, or fainting

  • Sudden, severe headache, problems with vision, speech, or walking, seizures, numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Unexplained muscle pain, tenderness, or weakness, fever, tiredness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, or red skin rash

Less Serious Side Effects

  • Joint pain

  • Stuffy or runny nose, sore throat

  • Diarrhea, upset stomach