What is Azacitidine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Azacitidine overview

BRAND NAMES:

  • PremierPro Rx azaCITIDine, Vidaza, Vidaza, Vidaza

Generic Names:

  • Azacitidine

Uses:

  • Treats certain blood related cancers.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Azacitidine used for?

What form(s) does Azacitidine come in

  • Injectable

What are common Azacitidine doses?

  • Suspension Reconstituted 100MG

Common Azacitidine prescriptions

  • azaCITIDine
    100mg suspension reconstituted

How to take Azacitidine

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • A nurse or other trained health professional will give you this medicine. You may also be taught how to give your medicine at home. This medicine is given as a shot under your skin or into a vein.

  • You may also receive medicines to help prevent nausea and vomiting.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • You may also receive medicines to help prevent nausea and vomiting.

  • You may also receive medicines to help prevent nausea and vomiting.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • A nurse or other trained health professional will give you this medicine. You may also be taught how to give your medicine at home. This medicine is given as a shot under your skin or into a vein.

What to do if you miss a dose of Azacitidine

Azacitidine contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to azacitidine or mannitol, or you are pregnant or breastfeeding.

Azacitidine warnings

  • Unusual bleeding, bruising, or weakness

  • Swelling in your hands, ankles, feet, or face

  • Skin wound that does not heal or looks infected (red and swollen)

  • Shortness of breath, cold sweat, and bluish skin

  • Seizures or tremors

  • Lightheadedness, dizziness, or fainting

  • Pain, redness, or swelling where the shot is given

  • Injection routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant.

  • Tell your doctor if you have kidney disease, liver disease (including tumors), or an infection.

  • This medicine may cause tumor lysis syndrome.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Fever, chills, cough, runny or stuffy nose, sore throat, and body aches

Azacitidine interactions

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell your doctor if you have liver disease, kidney disease, or any infections.

  • Do not breastfeed while you are being given this medicine.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

Azacitidine side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blood in your urine or stools

  • Change in how much or how often you urinate, painful urination

  • Chest pain, trouble breathing

  • Fever, chills, cough, runny or stuffy nose, sore throat, and body aches

  • Joint pain or stiffness, lower back or side pain, rapid weight gain, swelling in your hands, ankles, feet, or face

  • Unusual bleeding, bruising, or weakness

Less Serious Side Effects

  • Constipation, diarrhea, nausea, or vomiting

  • Pain, redness, or swelling where the shot was given

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