What is Busulfex? Uses, warnings & side effects

Updated May 14, 2025  •  Published Feb 15, 2024

Busulfex overview

BRAND NAMES:

  • Busulfex, Busulfex Novaplus

Generic Names:

  • Busulfex

Uses:

  • Treats certain kinds of leukemia and prepares the body for a stem cell transplant.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Busulfex used for?

What form(s) does Busulfex come in?

  • Injectable

What are common Busulfex dosages?

  • Vial 10ml of 6mg/ml

How to take Busulfex

  • This medicine is very strong. Make sure you understand why you are receiving it and the risks and benefits of treatment.

  • You will receive this medicine while you are in a hospital or chemotherapy treatment center.

  • Your medicine will be given through a tube called a central venous catheter that is put into your chest.

  • Before you receive busulfan, you will be given medicines to help prevent vomiting and other side effects.

What to do if you miss a dose of Busulfex

Busulfex contraindications - Who shouldn't take Busulfex?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to busulfan.

Busulfex warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • Tell your doctor if you had a seizure or head injury, or if you have ever received radiation treatments, other stem cell transplants, or other types of chemotherapy.

  • Your doctor will need to check your blood at regular times during your treatment.

  • Busulfan lowers your body's ability to fight infection. Avoid anyone who has a cold or other infection.

  • Busulfan may increase your risk for other types of cancer or a recurrence of leukemia.

Busulfex interactions & what to avoid when taking Busulfex

  • Tell your doctor all other medicines you are taking or have taken within the week before you receive busulfan.

  • Tell your doctor if you had a seizure or head injury, or if you have ever received radiation treatments, other stem cell transplants, or other types of chemotherapy.

  • Your doctor will need to check your blood at regular times during your treatment.

  • Busulfan lowers your body's ability to fight infection. Avoid anyone who has a cold or other infection.

  • Busulfan may increase your risk for other types of cancer or a recurrence of leukemia.

Busulfex side effects - How does Busulfex make you feel?

Serious Side Effects

  • Back pain

  • Diarrhea, nausea, or vomiting

  • Fever, chills, or sore throat

  • Sores or ulcers on your lips or in your mouth

  • Trouble sleeping

Less Serious Side Effects

  • Loss of appetite or stomach pain

  • Change in menstrual periods

  • Trouble sleeping

  • Skin rash

  • Anxiety or headache

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