What is Clinimix E/Dextrose (2.75/5): Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Feb 16, 2024

Clinimix E/Dextrose (2.75/5) overview

BRAND NAMES:

  • Clinimix E 4.25/25, Clinimix E 5/20, Clinimix, Clinimix E 4.25/10, Clinimix E 5/15, Clinimix E 2.75/5, Clinimix E 4.25/5, Clinimix E 5/25, Clinimix E 2.75/10, Aminosyn, Aminosyn (pH6), Aminosyn HBC, Aminosyn II, Aminosyn II with Electrolytes, Aminosyn M w/Electrolytes, Aminosyn-PF, Aminosyn-RF, Aminosyn With Electrolytes

Generic Names:

  • Clinimix E/Dextrose (2.75/5)

Uses:

  • Provides your body with needed calories, proteins, and electrolytes when oral nutrition is not enough or is impossible. Also treats negative nitrogen balance in the blood., Parenteral nutrition provides your body with protein, vitamins, minerals, and other nutrients. Total parenteral nutrition (TPN) provides all of your daily nutrition. Peripheral parenteral nutrition (PPN) gives you some of the nutrition you need. TPN and PPN solutions are given when you cannot eat or cannot get enough nutrition from the food that you do eat.

Therapeutic Classes:

  • Parenteral Amino Acids

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Clinimix E/Dextrose (2.75/5) used for?

What form(s) does Clinimix E/Dextrose (2.75/5) come in

  • Injectable

What are common Clinimix E/Dextrose (2.75/5) doses?

  • Plas Cont 1000ml of 2.75%

How to take Clinimix E/Dextrose (2.75/5)

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • TPN and PPN solutions are usually made by the pharmacist for your specific medical needs. Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Check the liquid in the IV bag before you use this medicine. Do not use it if the bag has a leak or the liquid is cloudy or has solid pieces in it. Get a new bag and tell your caregiver.

  • Injection routeUse a new needle and syringe each time you inject your medicine.

What to do if you miss a dose of Clinimix E/Dextrose (2.75/5)

  • You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

  • Injection routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Clinimix E/Dextrose (2.75/5) contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to amino acids or dextrose, or if you have an inborn error of amino acid metabolism, pulmonary edema (fluid in the lungs), or acidosis (too much acid in the blood).

  • Make sure the doctor knows about any severe health problems you have, including liver or kidney disease, or trouble urinating. Tell the doctor about any allergy you have, especially if you are allergic to amino acids or sulfites.

Clinimix E/Dextrose (2.75/5) warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine may cause the following problems:Blood clot in the lungs or veinsIncreased risk of infections, including sepsisRefeeding syndrome (in severely undernourished patients)High blood sugarLiver problems, including parenteral nutrition associated liver disease (PNALD)Electrolyte imbalance

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, diabetes, or lung or breathing problems.

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, asthma, or other breathing problems. Tell your doctor if you have mineral level problems in your blood (such as abnormal electrolyte levels, which may include high potassium levels or low calcium). Make sure your doctor knows if you have heart disease, stomach bleeding, or circulation problems, such as heart failure or blood-clotting problems.

  • Your IV could cause an infection. Carefully follow all instructions about how to keep the IV area clean and how to handle the TPN or PPN solution. Tell your caregiver if you have a fever; redness, swelling, or pain around the IV needle; or any other symptoms that resemble an infection.

  • Redness, warmth, swelling, or a lump where the needle is placed

  • Trouble breathing

  • Unexplained fever or chills

Clinimix E/Dextrose (2.75/5) interactions

  • Do not give this medicine together with ceftriaxone in children younger than 28 days of age (neonates).

  • Make sure your doctor knows if you are also using tetracycline. Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Do not add anything to the solution unless your doctor or other health caregiver has told you to.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Clinimix E/Dextrose (2.75/5) side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Chest pain, trouble breathing, coughing up blood, cold sweat, bluish-colored skin

  • Fever, chills, cough, sore throat, body aches

  • Change in how much or how often you urinate, bloody urine, painful or difficult urination, lower back or side pain

  • Trouble breathing

  • Confusion, fainting

  • Unexplained fever or chills

  • Change in how much or how often you urinate

  • Redness, warmth, swelling, or a lump where the needle is placed

Less Serious Side Effects

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Nausea or vomiting

  • Warmth or redness in your face, neck, arms, or upper chest

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