What is Cycloserine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Cycloserine overview

BRAND NAMES:

  • Seromycin

Generic Names:

  • Cycloserine

Uses:

  • Treats tuberculosis (TB). Sometimes used to treat urinary tract infections (UTIs).

Therapeutic Classes:

  • Antitubercular

Forms:

  • Capsule

How it’s taken:

  • By mouth

What is Cycloserine used for?

Cycloserine is a prescription-only medication that is used in combination with other drugs to treat tuberculosis. Tuberculosis is a bacterial infection that affects the lungs. Cycloserine works by reducing the growth of harmful bacteria within the body. Cycloserine can also be used to treat urinary tract infections (UTI).

What form(s) does Cycloserine come in

  • Capsule

What are common Cycloserine doses?

  • Capsule 250MG

Common Cycloserine prescriptions

  • cycloSERINE
    250mg capsule

How to take Cycloserine

  • Your doctor will tell you how much medicine to take and how often.

  • Take this medicine on a regular schedule. Keep taking the medicine for as long as your doctor has ordered, even if you are feeling better. If you stop the medicine too soon, your infection may not completely go away.

  • You may take this medicine with food or on an empty stomach.

  • Your doctor will tell you how much medicine to take and how often.

  • Take this medicine on a regular schedule. Keep taking the medicine for as long as your doctor has ordered, even if you are feeling better. If you stop the medicine too soon, your infection may not completely go away.

  • You may take this medicine with food or on an empty stomach.

What to do if you miss a dose of Cycloserine

  • Take the missed dose as soon as possible, unless it is almost time for your next dose.

  • Skip the missed dose if it is almost time for your next regular dose.

  • You should not use two doses at the same time.

Cycloserine contraindications

  • You should not use this medicine if you have had an allergic reaction to cycloserine. You should not use cycloserine if you drink large amounts of alcohol or have seizures (epilepsy), mental problems, depression, severe anxiety, or severe kidney disease.

Cycloserine warnings

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.

  • Tell your doctor right away if you become depressed or start to have thoughts about hurting yourself.

  • This medicine may make you dizzy or drowsy. If it does, avoid driving or using machinery. Tell your doctor if these symptoms do not go away.

  • Severe anxiety, confusion, memory loss

  • Changes in your personality such as aggressive behavior

  • Rash or hives

  • Trouble talking

Cycloserine interactions

  • Do not drink alcohol while taking cycloserine. You are more likely to have serious side effects such as seizures if you drink alcohol while taking this medicine.

  • Make sure your doctor knows if you are also taking ethionamide (Trecator-SC®) or isoniazid (INH®).

  • This medicine may make you dizzy or drowsy. If it does, avoid driving or using machinery. Tell your doctor if these symptoms do not go away.

Cycloserine side effects

Serious Side Effects

  • Severe anxiety, confusion, memory loss

  • Trouble talking

  • Depressed mood, thoughts of hurting yourself

  • Rash or hives

  • Seizures

  • Changes in your personality such as aggressive behavior

  • Trembling or tremors

Less Serious Side Effects

  • Headache

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